Details of Disease | DrugMAP

General Information of Disease (ID: DISPJ9QY)

Disease Name	Heterotaxy, visceral, 2, autosomal
Synonyms	Htx; HTX2; DTGA2; transposition of the great arteries, dextro-looped 2; heterotaxy, visceral, 2, autosomal
Disease Hierarchy	DIS1DV90: Visceral heterotaxy DISPXJ8X: Transposition of the great arteries DISPJ9QY: Heterotaxy, visceral, 2, autosomal
Disease Identifiers	MONDO ID MONDO_0011546 UMLS CUI C1415817 OMIM ID 605376 MedGen ID 237904

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ACVR2B	TTLFRKS	Strong	Biomarker	[1]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
NT5C1A	OTS7UF36	Disputed	Genetic Variation	[2]
CFC1	OT5DHGI8	Strong	Autosomal dominant	[3]
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References

1	The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse.Genes Dev. 1997 Jul 15;11(14):1812-26. doi: 10.1101/gad.11.14.1812.
2	Effect of Calcineurin Inhibitor-Free, Everolimus-Based Immunosuppressive Regimen on Albuminuria and Glomerular Filtration Rate After Heart Transplantation.Transplantation. 2017 Nov;101(11):2793-2800. doi: 10.1097/TP.0000000000001706.
3	Flexible and scalable diagnostic filtering of genomic variants using G2P with Ensembl VEP. Nat Commun. 2019 May 30;10(1):2373. doi: 10.1038/s41467-019-10016-3.