Details of Disease

General Information of Disease (ID: DISQ7HHE)

Disease Name Endemic goiter
Synonyms iodine-deficiency-related endemic goiter; simple goiter; simple goitre; iodine-deficiency-related endemic goitre
Definition Thyroid gland enlargement caused by inadequate dietary iodine intake. It occurs in areas in which the soil lacks iodine compounds or there is low seafood consumption.
Disease Hierarchy
DISLCGI6: Goiter
DIS1UUNY: Malnutrition
DISQ7HHE: Endemic goiter
Disease Identifiers
MONDO ID
MONDO_0006742
UMLS CUI
C0018022
MedGen ID
5357
SNOMED CT ID
267369002

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
TG OT3ELHIJ moderate Genetic Variation [1]
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References

1 New insights into thyroglobulin gene: molecular analysis of seven novel mutations associated with goiter and hypothyroidism.Mol Cell Endocrinol. 2013 Jan 30;365(2):277-91. doi: 10.1016/j.mce.2012.11.002. Epub 2012 Nov 16.