Details of Disease

General Information of Disease (ID: DISR0RPX)

• Disease Name: Grade IV malignant glioma
• Disease Class: 2A00: Brain cancer
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISR0RPX: Grade IV malignant glioma
• ICD Code:
  ICD-11: ICD-11: 2A00.0
  ICD-10: ICD-10: C71
  ICD-9: ICD-9: 191
  Expand ICD-11: 2A00.11; 2A00.00
  Expand ICD-10: C71
  Expand ICD-9: 191

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
VAL-083	DM9J5Q4	Phase 3	Small molecular drug	[1]

This Disease is Treated as An Indication in 1 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Rilotumumab	DMD8ZSW	Discontinued in Phase 2	Antibody	[2]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] ClinicalTrials.gov (NCT01478178) Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma. U.S. National Institutes of Health.
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7986).