Details of Disease

General Information of Disease (ID: DISR4ZRW)

Disease Name Tooth agenesis, selective, 4
Synonyms
tooth agenesis, selective, 4, with or without ectodermal dysplasia; lateral incisors, absence of; succedaneous teeth, agenesis of; lateral incisors, pegged or missing; STHAG4; tooth agenesis, selective, 4; tooth agenesis, selective, type 4; tooth agenesis caused by mutation in WNT10A; WNT10A tooth agenesis
Definition Any tooth agenesis in which the cause of the disease is a mutation in the WNT10A gene.
Disease Hierarchy
DIS7C7EV: Ectodermal dysplasia WNT10A related
DIS1PWC7: Tooth agenesis
DISR4ZRW: Tooth agenesis, selective, 4
Disease Identifiers
MONDO ID
MONDO_0007881
MESH ID
C563634
UMLS CUI
C1835492
OMIM ID
150400
MedGen ID
372057

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
WNT10A OTJ0DNZI Strong Autosomal dominant [1]
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References

1 Mutation in WNT10A is associated with an autosomal recessive ectodermal dysplasia: the odonto-onycho-dermal dysplasia. Am J Hum Genet. 2007 Oct;81(4):821-8. doi: 10.1086/520064. Epub 2007 Aug 9.