Details of Disease

General Information of Disease (ID: DISS4GU8)

• Disease Name: Xerostomia
• Disease Class: DA02: Lips/oral mucosa miscellaneous disorder
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISS4GU8: Xerostomia
• ICD Code:
  ICD-11: ICD-11: DA02.1
  ICD-10: ICD-10: R68, R68.2
  ICD-9: ICD-9: 527.7
  Expand ICD-11: 'DA02.1
  Expand ICD-10: 'R68; 'R68.2
  Expand ICD-9: 527.7
• Disease Identifiers:
  MESH ID: D014987
  MedGen ID: 22735
  HPO ID: HP:0000217
  SNOMED CT ID: 300268000

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
APD-515	DM9LZ0M	Phase 2	NA	[1]
AAV-AQP1	DMI27RF	Phase 1/2	Gene therapy	[2]

This Disease is Treated as An Indication in 1 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Physostigmine	DM2N0TO	Discontinued in Phase 2	Small molecular drug	[3]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033659)
• [2] Clinical pipeline report, company report or official report of MeiraGTx.
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6598).