Details of Disease

General Information of Disease (ID: DISSC9FY)

Disease Name Spermatogenic failure 13
Synonyms SPGF13; TAF4B azoospermia; spermatogenic failure 13; azoospermia caused by mutation in TAF4B; spermatogenic failure type 13
Definition Any azoospermia in which the cause of the disease is a mutation in the TAF4B gene.
Disease Hierarchy
DIS3D1AI: Spermatogenic failure
DISSC9FY: Spermatogenic failure 13
Disease Identifiers
MONDO ID
MONDO_0014365
UMLS CUI
C4014449
OMIM ID
615841
MedGen ID
862886

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
TAF4B OTCICY31 Limited Autosomal recessive [1]
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References

1 Maintenance of spermatogenesis requires TAF4b, a gonad-specific subunit of TFIID. Genes Dev. 2005 Apr 1;19(7):794-803. doi: 10.1101/gad.1290105. Epub 2005 Mar 17.