Details of Disease

General Information of Disease (ID: DISSEH6G)

Disease Name	Hyponatraemia
Synonyms	hypoaldosteronism; rare hypoaldosteronism
Disease Class	5C72: Hypo-osmolality/hyponatraemia
Definition	Editor note: we place the GARD class here as it is implicitly rare
Disease Hierarchy	DISFS818: Adrenal gland disorder DISSEH6G: Hyponatraemia
ICD Code	ICD-11 ICD-11: 5C72 ICD-10 ICD-10: E87 ICD-9 ICD-9: 276.1 Expand ICD-11 5C72 Expand ICD-10 E87 Expand ICD-9 276.1
Disease Identifiers	MONDO ID MONDO_0015900 UMLS CUI C0857899 MedGen ID 208996 HPO ID HP:0004319 Orphanet ID 181419

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 3 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Mozavaptan	DMZ905C	Approved	Small molecular drug	[1]
Sodium Acetate Anhydrous	DMH21E0	Approved	Small molecular drug	[1]
Tolvaptan	DMIWFRL	Approved	Small molecular drug	[2]
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This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Lixivaptan	DMDN4ZP	Phase 3	Small molecular drug	[3]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2226).
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2238).