Details of Disease

General Information of Disease (ID: DISVJQ2R)

• Disease Name: Reperfusion injury
• Disease Class: ND56: Unspecific body region injury
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISVJQ2R: Reperfusion injury
• ICD Code: ICD-11: ICD-11: ND56.Z

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
SPI-1005	DM6XFHS	Approved	Small molecular drug	[1]

This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
APT070	DM0DE26	Phase 3	NA	[2]
KAI-9803/ BMS-875944	DMTN9D7	Phase 2	Combination drug	[3]
PMID18163548C4	DMHPME3	Clinical trial	Small molecular drug	[4]

This Disease is Treated as An Indication in 2 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
HRC-102	DMJACXN	Terminated	NA	[5]
TH-9229	DMG1MPD	Terminated	NA	[6]

This Disease is Treated as An Indication in 4 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
EU-C-002	DM1MSSF	Investigative	NA	[7]
FG-65155	DMTL3ZP	Investigative	NA	[7]
XGP-610	DMOA6YM	Investigative	NA	[7]
ZJM-289	DMB1IKH	Investigative	NA	[7]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Advances in ischemic stroke treatment: neuroprotective and combination therapies. Expert Opin Emerg Drugs. 2007 Mar;12(1):97-112.
• [2] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012111)
• [3] Clinical pipeline report, company report or official report of Bristol-Myers Squibb.
• [4] Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator. J Med Chem. 2008 Jan 24;51(2):183-6.
• [5] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016740)
• [6] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008159)
• [7] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.