Details of Disease

General Information of Disease (ID: DISVMFVD)

Disease Name	Tetanus
Synonyms	lockjaw; Clostridium tetani infectious disease of the nervous system; Clostridium tetani caused infectious disease of the nervous system; infection due to Clostridium tetani; clostridial tetanus
Disease Class	1C13: Tetanus
Definition	A serious infectious disorder that follows wound contamination by the Gram-positive bacterium Clostridium tetani. The bacteria produce a neurotoxin called tetanospasmin, which causes muscle spasm in the jaw and other anatomic sites.\|We treat tetanus and infection due to Clostridium tetani as synonymous
Disease Hierarchy	DISKYOX0: Clostridium infection DIS8ZVFW: Primary bacterial infectious disease DISOE8QI: Infectious disorder of the nervous system DISVMFVD: Tetanus
ICD Code	ICD-11 ICD-11: 1C13 ICD-10 ICD-10: A30-A49, A35
Disease Identifiers	MONDO ID MONDO_0005526 MESH ID D013742 UMLS CUI C0039614 MedGen ID 21489 Orphanet ID 3299 SNOMED CT ID 276202003

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Diazepam	DM08E9O	Approved	Small molecular drug	[1]
Infanrix hexa	DM4DCZX	Approved in EU	Vaccine	[2]
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This Disease is Treated as An Indication in 4 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Benzylpenicillin	DMS9503	Phase 3	Small molecular drug	[3]
DTP-HepB-Polio-Hib	DMVDJ45	Phase 3	NA	[4]
Shan 6	DMGSX7D	Phase 3	NA	[5]
SP0173	DMAYY9O	Phase 1/2	Vaccine	[6]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Diazepam FDA Label
2	EU Approved Drug Products from EU Official Website.
3	Benzathine penicillin, metronidazole and benzyl penicillin in the treatment of tetanus: a randomized, controlled trial. Ann Trop Med Parasitol. 2004 Jan;98(1):59-63.
4	Clinical pipeline report, company report or official report of Sanofi Pasteur.
5	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
6	ClinicalTrials.gov (NCT02587520) Study of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed in Healthy Subjects. U.S. National Institutes of Health.