Details of Disease

General Information of Disease (ID: DISX0ETB)

Disease Name Dilated cardiomyopathy 1Y
Synonyms
left ventricular noncompaction 9; cardiomyopathy, dilated, 1Y; dilated cardiomyopathy type 1Y; familial isolated dilated cardiomyopathy caused by mutation in TPM1; TPM1 familial isolated dilated cardiomyopathy; cardiomyopathy, dilated, type 1Y; CMD1Y
Definition Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the TPM1 gene.
Disease Hierarchy
DISJ4QEG: Left ventricular noncompaction
DISX0ETB: Dilated cardiomyopathy 1Y
Disease Identifiers
MONDO ID
MONDO_0012744
MESH ID
C567507
UMLS CUI
C2678476
OMIM ID
611878
MedGen ID
437215

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
TPM1 OTD73X6R Strong Autosomal dominant [1]
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References

1 Mouse model of a familial hypertrophic cardiomyopathy mutation in alpha-tropomyosin manifests cardiac dysfunction. Circ Res. 1999 Jul 9;85(1):47-56. doi: 10.1161/01.res.85.1.47.