Details of Disease

General Information of Disease (ID: DISXMEII)

Disease Name Tinea infection
Synonyms ringworm; Tinea; Tinea disease or disorder; Tinea infection; Tinea caused disease or disorder; Tinea infectious disease
Definition A skin infection caused by a fungus.|Editor note: consider obsoleting as this is a loose grouping
Disease Hierarchy
DIS9K7PB: Mycoses
DIS1MY8X: Cutaneous mycosis
DIS3F9EY: Skin and skin-structure infection
DISXMEII: Tinea infection
Disease Identifiers
MONDO ID
MONDO_0005982
MESH ID
D014005
UMLS CUI
C0040247
MedGen ID
52757

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Benzocaine DMI18HW Approved Small molecular drug [1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
CLEC6A TTQ02HK Definitive Biomarker [2]
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This Disease Is Related to 2 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
CARD9 OTJ81AWD Limited Genetic Variation [3]
DEFB104A OTLQZR6K Definitive Altered Expression [4]
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References

1 Benzocaine: Review on a Drug with Unfold Potential. Mini Rev Med Chem. 2020;20(1):3-11.
2 Dectin-1 and Dectin-2 promote control of the fungal pathogen Trichophyton rubrum independently of IL-17 and adaptive immunity in experimental deep dermatophytosis.Innate Immun. 2016 Jul;22(5):316-24. doi: 10.1177/1753425916645392. Epub 2016 Apr 26.
3 Novel CARD9 mutation in a patient with chronic invasive dermatophyte infection (tinea profunda).J Cutan Pathol. 2020 Feb;47(2):166-170. doi: 10.1111/cup.13574. Epub 2019 Oct 29.
4 Low DEFB4 copy number and high systemic hBD-2 and IL-22 levels are associated with dermatophytosis.J Invest Dermatol. 2015 Mar;135(3):750-758. doi: 10.1038/jid.2014.369. Epub 2014 Sep 1.