Details of Disease

Disease Name

black death; pestilential fever; pest; infection by Yersinia pestis; Yersiniosis; plague

Definition

Plague is a severe bacterial infection caused by the gram-negative bacterium Yersinia pestis.

Disease Hierarchy

DISGFCIX: Vector-borne disease

DIS8ZVFW: Primary bacterial infectious disease

DISJEIJ5: Yersinia infection

DISEM33Q: Infectious disease

DISY1PBI: Plague

Disease Identifiers

MONDO ID

MONDO_0019095

MESH ID

D010930

UMLS CUI

C0032064

MedGen ID

10785

Orphanet ID

707

SNOMED CT ID

58750007

General Information of Disease (ID: DISY1PBI)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Minocycline	DMVN5OH	Approved	Small molecular drug	[1]
Streptomycin	DME1LQN	Approved	Small molecular drug	[2]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
IL17A	TTG0MT6	Disputed	Biomarker	[3]
------------------------------------------------------------------------------------

References

1	Minocycline FDA Label
2	Streptomycin FDA Label
3	Transcriptomic and innate immune responses to Yersinia pestis in the lymph node during bubonic plague.Infect Immun. 2010 Dec;78(12):5086-98. doi: 10.1128/IAI.00256-10. Epub 2010 Sep 27.