Details of Disease

General Information of Disease (ID: DISYCORK)

• Disease Name: Otitis externa
• Synonyms: infectious otitis externa; outer Ear infection; swimmer's ear; swimmer's Ear; otitis externa; external Ear infection
• Disease Class: AA00-AA13: Otitis externa
• Definition: Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.
• Disease Hierarchy:
  DISQZWRX: External ear disorder
  DIS8ZWQ4: Ear infection
  DIS0DF0D: Post-infectious disorder
  DISYCORK: Otitis externa
• ICD Code: ICD-11: ICD-11: AA00-AA13
• Disease Identifiers:
  MONDO ID: MONDO_0004795
  MESH ID: D010032
  UMLS CUI: C0029878
  MedGen ID: 10505
  HPO ID: HP:0410017
  SNOMED CT ID: 3135009

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Cetraxal Otic	DMX9K3W	Phase 3	NA	[1]
FST-201	DM1YVLM	Phase 3	NA	[2]
DPK 060	DMSUSMU	Phase 2	Peptide	[3]

This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
FST-200	DMC5AJO	Investigative	NA	[4]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Chem Biol. 2010 May 28;17(5):421-33.
• [2] ClinicalTrials.gov (NCT00945646) FST-201 In The Treatment of Acute Fungal Otitis Externa. U.S. National Institutes of Health.
• [3] ClinicalTrials.gov (NCT01447017) A Study of DPK-060 to Investigate Clinical Safety and Efficacy in Patients With Acute External Otitis. U.S. National Institutes of Health.
• [4] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
• [5] Emerging therapies for the treatment and prevention of otitis media. Expert Opin Emerg Drugs. 2006 May;11(2):251-64.