Details of Disease

General Information of Disease (ID: DISZ3PL0)

• Disease Name: Hunter syndrome
• Disease Class: 5C56: Lysosomal disease
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISZ3PL0: Hunter syndrome
• ICD Code:
  ICD-11: ICD-11: 5C56.31
  ICD-10: ICD-10: E76.1
  Expand ICD-11: '5C56.31
  Expand ICD-10: 'E76.1
• Disease Identifiers:
  MONDO ID: MONDO_0018983
  MESH ID: D020333
  UMLS CUI: C0040381
  MedGen ID: 21197
  Orphanet ID: 64686
  SNOMED CT ID: 95794005

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Idursulfase	DM30SXV	Approved	NA	[1]

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Recombinant human iduronate-2-sulfatase	DMOWQAF	Phase 3	NA	[2]
AGT-182	DML79KE	Phase 1	Antibody	[3]

This Disease is Treated as An Indication in 2 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
JR-032	DMDOR6T	Investigative	NA	[4]
LG-1041	DM324PY	Investigative	NA	[4]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] 2006 drug approvals: finding the niche. Nat Rev Drug Discov. 2007 Feb;6(2):99-101.
• [2] ClinicalTrials.gov (NCT01645189) Safety and Efficacy of Hunterase. U.S. National Institutes of Health.
• [3] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [4] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.