Details of Disease

General Information of Disease (ID: DISZA6J9)

Disease Name Sporotrichosis
Synonyms rose gardener's disease
Definition
The commonest and least serious of the deep mycoses, characterized by nodular lesions of the cutaneous and subcutaneous tissues. It is caused by inhalation of contaminated dust or by infection of a wound.
Disease Hierarchy
DIS9K7PB: Mycoses
DISZA6J9: Sporotrichosis
Disease Identifiers
MONDO ID
MONDO_0005968
MESH ID
D013174
UMLS CUI
C0038034
MedGen ID
21298
Orphanet ID
826
SNOMED CT ID
42094007

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 2 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
F12 TTRJSMV Strong Biomarker [1]
MASP2 TTR01E9 Strong Genetic Variation [2]
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This Disease Is Related to 2 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
PHF5A OTS94JFM Strong Biomarker [3]
PRSS2 OTOMVUWL Strong Biomarker [2]
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References

1 Epidemiological data and molecular characterization (mtDNA) of Sporothrix schenckii in 13 cases from Mexico.Int J Dermatol. 2007 Feb;46(2):177-9. doi: 10.1111/j.1365-4632.2006.03036.x.
2 Mannose-Binding Lectin and Mannose-Binding Lectin-Associated Serine Protease-2 Genotypes and Serum Levels in Patients with Sporotrichosis.Am J Trop Med Hyg. 2019 Dec;101(6):1322-1324. doi: 10.4269/ajtmh.19-0470.
3 Zoonotic sporotrichosis with greater severity in Rio de Janeiro, Brazil: 118 hospitalizations and 11 deaths in the last 2 decades in a reference institution.Med Mycol. 2020 Jan 1;58(1):141-143. doi: 10.1093/mmy/myz024.