Details of Disease

General Information of Disease (ID: DISZA94A)

• Disease Name: Acute radiation syndrome
• Synonyms: Acute radiation sickness
• Disease Class: NF00: Radiation effect
• Disease Hierarchy:
  DIS6SVEE: Syndromic disease
  DISBV50J: Acute disease
  DISZA94A: Acute radiation syndrome
• ICD Code:
  ICD-11: ICD-11: NF00
  ICD-10: ICD-10: T66
  ICD-9: ICD-9: 990
  Expand ICD-9: 990

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Pentetate calcium trisodium	DMI1R4F	Approved	Small molecular drug	[1]
Pentetate zinc trisodium	DM9U0VW	Approved	Small molecular drug	[1]

This Disease is Treated as An Indication in 7 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
PLX-R18	DM0DKF8	Phase 3	Cell therapy	[2]
Prochymal	DMWTCWM	Phase 3	NA	[3]
CBLB-502	DMK4FRU	Phase 2	NA	[4]
Beclomethasone dispropionate	DMJF6NU	Phase 1	NA	[5]
ON-01210.Na	DMWYEDX	Phase 1	Small molecular drug	[5]
ONO-01210	DM6P0AT	Phase 1	NA	[5]
STAT-600	DM3RSQK	Phase 1	Protein	[6]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] 2004 approvals: the demise of the blockbuster. Nat Rev Drug Discov. 2005 Feb;4(2):93-4.
• [2] Clinical pipeline report, company report or official report of Pluristem Therapeutics.
• [3] ClinicalTrials.gov (NCT00482092) Evaluation of PROCHYMAL Adult Human Stem Cells for Treatment-resistant Moderate-to-severe Crohn's Disease. U.S. National Institutes of Health.
• [4] Recombinant TLR5 agonist CBLB502 promotes NK cell-mediated anti-CMV immunity in mice. PLoS One. 2014 May 30;9(5):e96165.
• [5] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [6] Clinical pipeline report, company report or official report of Statera Biopharma