Details of Drug-Metabolizing Enzyme (DME)

General Information of Drug-Metabolizing Enzyme (DME) (ID: DE46IH1)

DME Name	Beta-glucosidase (bglA)
Synonyms	Periplasmic beta-glucosidase; Glucan endo-1 3-beta-D-glucosidase; Beta-D-glucosidase; SAMN02745126_03145
Gene Name	bglA
UniProt ID	A0A1T4QCU7_9PROT
INTEDE ID	DME1843
EC Number	EC: 3.2.1.21 Hydrolases Glycosylase O/S-glycosyl compound glycosidase EC: 3.2.1.21
Lineage	Species: Enhydrobacter aerosaccus Kingdom: Bacteria Phylum: Proteobacteria Class: Alphaproteobacteria Order: Rhodospirillales Family: Enhydrobacter Genus: Enhydrobacter Species: Enhydrobacter aerosaccus
Tissue Distribution	Primarily distributed in human gut.
Sequence	MPARLSRRDLAGAAVLTAALGATIAATEADAAPKSQSGFPDGFLWGTATAAYQVEGAVHE DGRGPSIWDTFSHLPGKIRDGSTGDVSVDHYHRYKEDVALMKALGATSYRFSIAWPRVFP DGTGTPNPKGLDFYDRLVDELLKAGIKPFATLYHWDLPQALQDRGGWQSRDTAQAFGAYA GYVANKLGDRVENFFTLNEMLTFVEHGHAAGVFAPGLTLPPQGVNQVRHHAVLAHGLGVQ AMRASARRPIRIGPAENITIGIPAVETPENIRAAEIATREFNAPYLTVMLEGRYTDAYLA ATGADAPKFTAEDLKIIASPVDFVGLNVYTPSFFVVATDAAPHYRALPLPSSYPHMASPW LTIGPEALYWAPRHAATLWNAKEIYITENGTSSADQLAEDGQIYDTDRIMYLRNYLTQLQ RATAEGVPVRGYFLWSLLDNFEWADGYATRFGLVHVDYTTQKRTPKLSAAFYREVIARNA VA
Function	This enzyme has wide specificity for beta-D-glucosides such as beta-D-galactosides, alpha-L-arabinosides, beta-D-xylosides, beta-D-fucosides.

Molecular Interaction Atlas (MIA) of This DME

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DME

1 Investigative Drug(s) Metabolized by This DME

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ginsenoside Rb1	DMF70AB	N. A.	N. A.	Investigative	[1]
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References

1	Genus Enhydrobacter Staley et al. 1987 should be recognized as a member of the family Rhodospirillaceae within the class Alphaproteobacteria. Microbiol Immunol. 2012 Jan;56(1):21-6.