Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DECMT89)
| DME Name | Chloramphenicolase (chlR) | ||||
|---|---|---|---|---|---|
| Synonyms | Chloramphenicol reductase; Enzyme chloramphenicolase; Reductase chloramphenicol | ||||
| Gene Name | chlR | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| EC Number | EC: 2.3.1.28 | ||||
| Lineage | Species: Proteus penneri | ||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Sequence |
MKKIDLNSWNRREHFAFFSQFDEPFFSIVAEVDCTVAYRKAKEQDIPFFIWYLYQSLLAA
NQVEPFRYRIIDNEVVVLDEIHASSTVAREDHTFGFTFMPYREDIKAFVAEALPEIERVQ QLEGLCFDEKTSRTDVIHYSSIPWINFTALTHARHNARKDSVPKISFGQYQEKEGKLMMP VSVTVHHGLMDGYHVGLFLTKFQKLLES |
||||
| Function | This enzyme catalyzes the hydrolysis of the amide bond in chloramphenicol. | ||||
Molecular Interaction Atlas (MIA) of This DME
| Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
1 Approved Drug(s) Metabolized by This DME
|
||||||||||||||||||||||||||||