Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DEMUBWL)
| DME Name | Chloramphenicolase (chlR) | ||||
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| Synonyms | Chloramphenicol reductase; Enzyme chloramphenicolase; Reductase chloramphenicol | ||||
| Gene Name | chlR | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| EC Number | EC: 2.3.1.28 | ||||
| Lineage | Species: Bacillus pumilus | ||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Sequence |
MKKIDLNSWNRREHFAFFSQFDEPFFSIVAEVDCTVAYRKAKEQDIPFFIWYLYQSLLAA
NQVEPFRYRIIDNEVVVLDEIHASSTVAREDHTFGFTFMPYREDIKAFVAEALPEIERVQ QLEGLCFDEKTSRTDVIHYSSIPWINFTALTHARHNARKDSVPKISFGQYQEKEGKLMMP VSVTVHHGLMDGYHVGLFLTKFQKLLES |
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| Function | This enzyme catalyzes the hydrolysis of the amide bond in chloramphenicol. | ||||
Molecular Interaction Atlas (MIA) of This DME
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1 Approved Drug(s) Metabolized by This DME
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