Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DEPCQ12)
| DME Name | Metallo-beta-lactamase (blaM) | ||||
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| Synonyms | Metallo-beta-lactamase NDM-1; New Delhi metallo-beta-lactamase-1; Metallo-beta-lactamase type 2c; Metallo-beta-lactamase type IIc; B2 metallo-beta-lactamase; Beta-lactamase type IIc; NDM-1; blaNDM-1 | ||||
| Gene Name | blaVIM-2 | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| EC Number | EC: 3.5.2.6 | ||||
| Lineage | Species: Achromobacter xylosoxidans | ||||
| Tissue Distribution | Primarily distributed in human stomach. | ||||
| Sequence |
MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ
SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS TDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH GLPGGLDLLKHTTNVVKAHTNRSVVE |
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| Function | This enzyme hydrolyzes beta-lactam. | ||||
Molecular Interaction Atlas (MIA) of This DME
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1 Approved Drug(s) Metabolized by This DME
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