Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DERX7ML)
| DME Name | Beta-glucosidase (bglA) | ||||
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| Synonyms | Periplasmic beta-glucosidase; Glucan endo-1 3-beta-D-glucosidase; Beta-D-glucosidase; DCE60_07650 | ||||
| Gene Name | DCE60_07650 | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| EC Number | EC: 3.2.1.21 | ||||
| Lineage | Species: Coprococcus comes | ||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Sequence |
MMDMKNQVVLDWNQYVALARQTVAEGCVLLENKDQALPLVKDEKVAVFGRIQNHYYKSGT
GSGGMVNVSKVYGIVDGLRESGQVILDEELIRIYQDWEETHPFNEGEGWGNEPWCQEEME LTDEVVEAAGKRSETAIVIIGRTAGEDKDASDTKGSYQLTDVEEDLLTKVRKNFDKMIVL LNVGGLLDMSFTDRYQPEAVMYVWQGGMVGGLGTADVLTGAVSPSGHLTDTIAYKVADYP STPYFGDPDKNYYSEDIYVGYRYFETFAKDSVRYPFGYGLSYTTFEKSVVVFANEPEKQQ FTLHVTVSNVGLKKGKDVVQIYAEAPQGKLGKADKVLVGFAKTKELAPGESEEVEITVPY SRFASYDDSGITGHAYAFVLEAGTYHVFAGENVRSAECAGAFELADGLVIEQLCSALAPV EAFDRMKAAETENGYQVMMEAAPHHASNEKQRRQDHLPQEIRQTMGMHTLSDVADGSIGM DKFISELTDDDLTCIIRGEGMGSSLVTPGTAAAFGGVSKSLINRHGIPSVCCSDGPSGMR LDCGVKAFSLPNGTIIGCTFNTELVKELYTCTGYEMIAQKVDCLLGPGMNIHRHPLNGRN FEYFSEDPYVTGCFAGAMLEGLHAAGVTGAAKHFCANNQEMRRHFADPIVSERALREIYL KGFEMIVRSGVCDAIMTTYGPVNGVWTAGNYDLCTTILREEWGFKGIVMTDWWASINERG QEPDKINFAAMARAQNDIYMVCPDGSTNASGDNTAAALVDGRLKRAELQRNAANICGFVL DTEAMRRAMGCPTEVSIINRPAEPDDVDLSEVEFVRLDGDYELRLDTKESKAGVNYVLPF DVQKKGIYEIELIGSSDLSELAQMPCTLYYTNIPILSFTFHGTNGEDMVIKKEFDLHTRF SVMRLNVGKNGLHLKQIRFRYLREGKIWN |
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| Function | This enzyme has wide specificity for beta-D-glucosides such as beta-D-galactosides, alpha-L-arabinosides, beta-D-xylosides, beta-D-fucosides. | ||||
Molecular Interaction Atlas (MIA) of This DME
| Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||
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1 Investigative Drug(s) Metabolized by This DME
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