Details of Drug Off-Target (DOT)

General Information of Drug Off-Target (DOT) (ID: OTZB5FCN)

DOT Name	Putative glycosyltransferase ALG1L2 (ALG1L2)
Synonyms	EC 2.4.1.-
Gene Name	ALG1L2
UniProt ID	AG1L2_HUMAN
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
EC Number	2.4.1.-
Pfam ID	PF00534
Sequence	MGATAGWAVTVYDKPASFFKEAPLDLQHRLFMKLGSTHSPFRARSEPEDPDTERSAFTER DSGSGLVTRLHERPALLVSSTSWTEFEQLTLDGQNLPSLVCVITGKGPLREYYSRLIHQK HFQHIQVCIPWLEGRGLPPLLGSVDLDVCLDTSSSGLDLPMKVVDMFRCCLPACAVNFKC LHELVKHEENRLVFEDSEELAAQLQYFADAFLKLS
Function	Putative glycosyltransferase.

Molecular Interaction Atlas (MIA) of This DOT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DOT

1 Drug(s) Affected the Gene/Protein Processing of This DOT

Drug Name	Drug ID	Highest Status	Interaction	REF
Tretinoin	DM49DUI	Approved	Tretinoin decreases the expression of Putative glycosyltransferase ALG1L2 (ALG1L2).	[1]
------------------------------------------------------------------------------------

References

1	Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells. Cells. 2020 Nov 5;9(11):2423. doi: 10.3390/cells9112423.