Molecular Interaction Atlas (MIA) |
|
Indication(s) of AZD8055 |
Disease Entry |
ICD 11 |
Status |
REF |
Solid tumour/cancer |
2A00-2F9Z
|
Discontinued in Phase 1/2 |
[2] |
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AZD8055 Interacts with 1 DTT Molecule(s)
DTT Name |
DTT ID |
UniProt ID |
Mode of Action |
REF |
Serine/threonine-protein kinase mTOR (mTOR)
|
TTCJG29
|
MTOR_HUMAN
|
Inhibitor
|
[4] |
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AZD8055 Interacts with 2 DOT Molecule(s)
DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
Ribosomal protein S6 kinase beta-1 (RPS6KB1)
|
OTAELNGX
|
KS6B1_HUMAN
|
Decreases Phosphorylation
|
[5] |
RAC-alpha serine/threonine-protein kinase (AKT1)
|
OT8H2YY7
|
AKT1_HUMAN
|
Decreases Phosphorylation
|
[5] |
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Indication(s) of JQ1 |
Disease Entry |
ICD 11 |
Status |
REF |
Coronavirus Disease 2019 (COVID-19) |
1D6Y
|
Investigative |
[3] |
|
|
JQ1 Interacts with 1 DTT Molecule(s)
DTT Name |
DTT ID |
UniProt ID |
Mode of Action |
REF |
HUMAN bromodomain-containing protein 2 (BRD2)
|
TTNISW6
|
BRD2_HUMAN
|
Inhibitor
|
[3] |
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