Details of the Drug Combination

General Information of Drug Combination (ID: DCFIW64)

• Drug Combination Name: GDC-0084 + Panobinostat
• Indication: Hodgkin lymphoma; Status: Investigative [1]
• Component Drugs:
  GDC-0084 (DMA9SEY): N.A.
  Panobinostat (DM58WKG): Small molecular drug
• High-throughput Screening Result:
  Testing Cell Line: L-1236
  Zero Interaction Potency (ZIP) Score: 19.132
  Bliss Independence Score: 18.975
  Loewe Additivity Score: 3.623
  LHighest Single Agent (HSA) Score: 5.965

Molecular Interaction Atlas of This Drug Combination

Indication(s) of GDC-0084

Disease Entry	ICD 11	Status	REF
Glioblastoma of brain	2A00.00	Phase 2	[2]

GDC-0084 Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
PI3-kinase gamma (PIK3CG)	TTHBTOP	PK3CG_HUMAN	Inhibitor	[6]

Indication(s) of Panobinostat

Disease Entry	ICD 11	Status	REF
Chronic graft versus host disease	N.A.	Approved	[3]
Lung cancer	2C25.0	Approved	[3]
Multiple myeloma	2A83	Approved	[4]
Non-small-cell lung cancer	2C25.Y	Approved	[3]
Plasma cell myeloma	2A83.1	Approved	[3]
Primary cutaneous T-cell lymphoma	N.A.	Approved	[3]
Type-2 diabetes	5A11	Phase 3	[5]
Primary myelofibrosis	2A20.2	Phase 2	[5]

Panobinostat Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Histone deacetylase 1 (HDAC1)	TT6R7JZ	HDAC1_HUMAN	Inhibitor	[10]

Panobinostat Interacts with 1 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[11]

Panobinostat Interacts with 1 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 3A4 (CYP3A4)	DE4LYSA	CP3A4_HUMAN	Metabolism	[12]

Panobinostat Interacts with 1019 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Decreases Expression	[13]
DNA-directed RNA polymerase II subunit RPB1 (POLR2A)	OTHJQ1DZ	RPB1_HUMAN	Decreases Phosphorylation	[13]
Diphosphoinositol polyphosphate phosphohydrolase NUDT4B (NUDT4)	OTA6ICI2	NUD4B_HUMAN	Increases Expression	[7]
ADP-ribose glycohydrolase MACROD2 (MACROD2)	OTNQCHC6	MACD2_HUMAN	Decreases Expression	[7]
Transmembrane protein 218 (TMEM218)	OTM46L89	TM218_HUMAN	Decreases Expression	[7]
Cadherin-like and PC-esterase domain-containing protein 1 (CPED1)	OTJJPZOZ	CPED1_HUMAN	Increases Expression	[7]
Killer cell lectin-like receptor subfamily G member 2 (KLRG2)	OTBLEXSC	KLRG2_HUMAN	Increases Expression	[7]
Protein FAM149A (FAM149A)	OTMDM0RI	F149A_HUMAN	Decreases Expression	[7]
Developmental pluripotency-associated 5 protein (DPPA5)	OTLZC371	DPPA5_HUMAN	Increases Expression	[7]
Metalloprotease TIKI2 (TRABD2B)	OTI7B18G	TIKI2_HUMAN	Increases Expression	[7]
RNA binding protein fox-1 homolog 3 (RBFOX3)	OTL0F3D6	RFOX3_HUMAN	Decreases Expression	[7]
Coiled-coil domain-containing protein 69 (CCDC69)	OT43MI0R	CCD69_HUMAN	Increases Expression	[7]
Ras association domain-containing protein 10 (RASSF10)	OTGB7EBG	RASFA_HUMAN	Decreases Expression	[7]
Very-long-chain (HACD1)	OTEC7EP7	HACD1_HUMAN	Increases Expression	[7]
NALCN channel auxiliary factor 1 (NALF1)	OT8OMCFD	NALF1_HUMAN	Decreases Expression	[7]
Rab GTPase-activating protein 1-like, isoform 10 (RABGAP1L)	OT7QO47I	RBG10_HUMAN	Increases Expression	[7]
Alternative prion protein (PRNP)	OTE85L1Q	APRIO_HUMAN	Increases Expression	[7]
Suppressyn (ERVH48-1)	OT303JGE	SUPYN_HUMAN	Increases Expression	[7]
PDZ and LIM domain protein 1 (PDLIM1)	OT4EGCPG	PDLI1_HUMAN	Increases Expression	[7]
Activator of apoptosis harakiri (HRK)	OTR4GWJ0	HRK_HUMAN	Increases Expression	[7]
Proteinase-activated receptor 3 (F2RL2)	OT982ECU	PAR3_HUMAN	Decreases Expression	[7]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)	OTQ4W7MT	TR11B_HUMAN	Increases Expression	[7]
Sulfotransferase 1C2 (SULT1C2)	OT07MMZS	ST1C2_HUMAN	Increases Expression	[7]
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2)	OTKOZRZP	PLOD2_HUMAN	Increases Expression	[7]
Beta-1,3-N-acetylglucosaminyltransferase manic fringe (MFNG)	OTUX45ZF	MFNG_HUMAN	Decreases Expression	[7]
Podocalyxin (PODXL)	OTPNQXF3	PODXL_HUMAN	Increases Expression	[7]
E3 ubiquitin-protein ligase TRIM38 (TRIM38)	OT6SP1M9	TRI38_HUMAN	Increases Expression	[7]
Nuclear factor 1 B-type (NFIB)	OTX94PD0	NFIB_HUMAN	Increases Expression	[7]
Claudin-4 (CLDN4)	OT9C4PZ4	CLD4_HUMAN	Increases Expression	[7]
Class E basic helix-loop-helix protein 40 (BHLHE40)	OTITX14U	BHE40_HUMAN	Increases Expression	[7]
Suppressor of cytokine signaling 2 (SOCS2)	OTBPNKJQ	SOCS2_HUMAN	Increases Expression	[7]
Astrotactin-1 (ASTN1)	OT23FQIB	ASTN1_HUMAN	Decreases Expression	[7]
Suppressor of cytokine signaling 3 (SOCS3)	OTY183WJ	SOCS3_HUMAN	Decreases Expression	[7]
Cytoplasmic dynein 1 intermediate chain 1 (DYNC1I1)	OTFX1KCG	DC1I1_HUMAN	Increases Expression	[7]
Transmembrane gamma-carboxyglutamic acid protein 1 (PRRG1)	OTMH6OWG	TMG1_HUMAN	Increases Expression	[7]
Putative transcription factor Ovo-like 1 (OVOL1)	OTFJ62UI	OVOL1_HUMAN	Increases Expression	[7]
Neuropilin-1 (NRP1)	OTCGULYV	NRP1_HUMAN	Increases Expression	[7]
Tumor necrosis factor ligand superfamily member 11 (TNFSF11)	OTJEPKEQ	TNF11_HUMAN	Increases Expression	[7]
Probable proton-coupled zinc antiporter SLC30A4 (SLC30A4)	OTUYJNBS	ZNT4_HUMAN	Increases Expression	[7]
Interferon regulatory factor 6 (IRF6)	OTKJ44EV	IRF6_HUMAN	Increases Expression	[7]
Calmegin (CLGN)	OTEWVFQV	CLGN_HUMAN	Decreases Expression	[7]
Semaphorin-3E (SEMA3E)	OTD4S36H	SEM3E_HUMAN	Increases Expression	[7]
Serine/threonine-protein kinase DCLK1 (DCLK1)	OTVSPS98	DCLK1_HUMAN	Increases Expression	[7]
Angiopoietin-2 (ANGPT2)	OTEQK65P	ANGP2_HUMAN	Increases Expression	[7]
Phospholipid scramblase 1 (PLSCR1)	OTGY9B5T	PLS1_HUMAN	Increases Expression	[7]
Mitogen-activated protein kinase 13 (MAPK13)	OT0W9GE7	MK13_HUMAN	Increases Expression	[7]
DNA-directed RNA polymerase III subunit RPC7 (POLR3G)	OTU3TGQ9	RPC7_HUMAN	Increases Expression	[7]
Prosaposin receptor GPR37 (GPR37)	OTIMDDI3	GPR37_HUMAN	Increases Expression	[7]
Monocarboxylate transporter 5 (SLC16A4)	OT1YXBKC	MOT5_HUMAN	Increases Expression	[7]
TOX high mobility group box family member 3 (TOX3)	OTC9NR4W	TOX3_HUMAN	Decreases Expression	[7]
Suppressor of cytokine signaling 1 (SOCS1)	OTWA9KFU	SOCS1_HUMAN	Increases Expression	[7]
Regulator of G-protein signaling 5 (RGS5)	OTUY0Q2I	RGS5_HUMAN	Increases Expression	[7]
Leucine-rich repeat transmembrane protein FLRT2 (FLRT2)	OTGD8TID	FLRT2_HUMAN	Decreases Expression	[7]
Rho GTPase-activating protein 6 (ARHGAP6)	OTNVXXFX	RHG06_HUMAN	Increases Expression	[7]
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM12)	OTZKOTDB	ADA12_HUMAN	Decreases Expression	[7]
Proline dehydrogenase 1, mitochondrial (PRODH)	OT7SQ1C7	PROD_HUMAN	Increases Expression	[7]
Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1)	OTIK337D	TGFI1_HUMAN	Increases Expression	[7]
Phospholipid-transporting ATPase IC (ATP8B1)	OTALGS63	AT8B1_HUMAN	Increases Expression	[7]
Bcl-2-like protein 11 (BCL2L11)	OTNQQWFJ	B2L11_HUMAN	Decreases Expression	[7]
Carbonic anhydrase 12 (CA12)	OT6WNFU8	CAH12_HUMAN	Increases Expression	[7]
Synaptotagmin-7 (SYT7)	OTBWAOWY	SYT7_HUMAN	Increases Expression	[7]
Protein sprouty homolog 1 (SPRY1)	OT764FXI	SPY1_HUMAN	Decreases Expression	[7]
Zinc finger protein SNAI2 (SNAI2)	OT7Y8EJ2	SNAI2_HUMAN	Increases Expression	[7]
Synaptogyrin-1 (SYNGR1)	OT0MBUK5	SNG1_HUMAN	Increases Expression	[7]
Protocadherin-7 (PCDH7)	OTP091X8	PCDH7_HUMAN	Increases Expression	[7]
Kallikrein-8 (KLK8)	OTGVGHXY	KLK8_HUMAN	Increases Expression	[7]
Phospholipid-transporting ATPase IK (ATP8B3)	OTZOGEJO	AT8B3_HUMAN	Increases Expression	[7]
Periplakin (PPL)	OTTM4WDO	PEPL_HUMAN	Increases Expression	[7]
Lymphocyte antigen 75 (LY75)	OTDHBU0N	LY75_HUMAN	Increases Expression	[7]
BMP/retinoic acid-inducible neural-specific protein 1 (BRINP1)	OTEUVSCP	BRNP1_HUMAN	Increases Expression	[7]
Homeobox protein DLX-3 (DLX3)	OTARP5SQ	DLX3_HUMAN	Increases Expression	[7]
Plexin-C1 (PLXNC1)	OTJ5XKYY	PLXC1_HUMAN	Decreases Expression	[7]
Gremlin-1 (GREM1)	OTCK4IGV	GREM1_HUMAN	Increases Expression	[7]
Cyclin-T2 (CCNT2)	OTBDRH1J	CCNT2_HUMAN	Decreases Expression	[7]
Histone H2B type 1-K (H2BC12)	OTQ8V0KG	H2B1K_HUMAN	Decreases Expression	[7]
Growth arrest-specific protein 7 (GAS7)	OT0M5TNY	GAS7_HUMAN	Increases Expression	[7]
Protein diaphanous homolog 2 (DIAPH2)	OTBEYFEZ	DIAP2_HUMAN	Increases Expression	[7]
Inward rectifier potassium channel 13 (KCNJ13)	OTG1CNND	KCJ13_HUMAN	Decreases Expression	[7]
Plexin-A2 (PLXNA2)	OTNNBJMQ	PLXA2_HUMAN	Increases Expression	[7]
Frizzled-7 (FZD7)	OTTK3F6E	FZD7_HUMAN	Increases Expression	[7]
Slit homolog 1 protein (SLIT1)	OT35RBNT	SLIT1_HUMAN	Increases Expression	[7]
Slit homolog 3 protein (SLIT3)	OTU8MKEU	SLIT3_HUMAN	Increases Expression	[7]
Probable phospholipid-transporting ATPase IIA (ATP9A)	OT328F1L	ATP9A_HUMAN	Decreases Expression	[7]
Microfibrillar-associated protein 3-like (MFAP3L)	OTNMHSAH	MFA3L_HUMAN	Decreases Expression	[7]
Protein cordon-bleu (COBL)	OTTB4VFQ	COBL_HUMAN	Increases Expression	[7]
Astrotactin-2 (ASTN2)	OTF0W2FJ	ASTN2_HUMAN	Increases Expression	[7]
Calcium-transporting ATPase type 2C member 2 (ATP2C2)	OTGIHTYQ	AT2C2_HUMAN	Increases Expression	[7]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B)	OTL9I7LO	GA45B_HUMAN	Increases Expression	[7]
Core histone macro-H2A.1 (MACROH2A1)	OTV2DQDD	H2AY_HUMAN	Decreases Expression	[7]
Filamin-B (FLNB)	OTPCOYL6	FLNB_HUMAN	Increases Expression	[7]
Large neutral amino acids transporter small subunit 3 (SLC43A1)	OTQJQY3S	LAT3_HUMAN	Increases Expression	[7]
Transforming acidic coiled-coil-containing protein 1 (TACC1)	OTGX20TE	TACC1_HUMAN	Increases Expression	[7]
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1)	OTLMT95K	NDUB1_HUMAN	Decreases Expression	[7]
Glypican-4 (GPC4)	OTUJ14DW	GPC4_HUMAN	Decreases Expression	[7]
Disabled homolog 1 (DAB1)	OTPL9MA3	DAB1_HUMAN	Decreases Expression	[7]
Src kinase-associated phosphoprotein 2 (SKAP2)	OTSF44KP	SKAP2_HUMAN	Increases Expression	[7]
Forkhead box protein H1 (FOXH1)	OTEXJ9SL	FOXH1_HUMAN	Increases Expression	[7]
PR domain zinc finger protein 1 (PRDM1)	OTQLSVBS	PRDM1_HUMAN	Increases Expression	[7]
Scrapie-responsive protein 1 (SCRG1)	OTBE7V0P	SCRG1_HUMAN	Increases Expression	[7]
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12)	OTB4YBVT	S2512_HUMAN	Increases Expression	[7]
Leukocyte cell-derived chemotaxin 1 (CNMD)	OTHND8EL	CNMD_HUMAN	Increases Expression	[7]
Short-chain dehydrogenase/reductase 3 (DHRS3)	OTSK1DTP	DHRS3_HUMAN	Increases Expression	[7]
Serine/threonine-protein kinase PAK 3 (PAK3)	OT80M3BV	PAK3_HUMAN	Decreases Expression	[7]
Lysozyme-like protein 6 (LYZL6)	OT6XS67M	LYZL6_HUMAN	Increases Expression	[7]
Retinal dehydrogenase 2 (ALDH1A2)	OTJB560Z	AL1A2_HUMAN	Decreases Expression	[7]
Slit homolog 2 protein (SLIT2)	OTLS2RJ4	SLIT2_HUMAN	Increases Expression	[7]
Nucleolar protein 4 (NOL4)	OTWI587R	NOL4_HUMAN	Decreases Expression	[7]
Kelch repeat and BTB domain-containing protein 11 (KBTBD11)	OTBOY3WH	KBTBB_HUMAN	Decreases Expression	[7]
Unconventional myosin-Id (MYO1D)	OTP2RGPN	MYO1D_HUMAN	Increases Expression	[7]
Protein transport protein Sec24D (SEC24D)	OTXR3KC9	SC24D_HUMAN	Increases Expression	[7]
Neurofascin (NFASC)	OTBDUXZT	NFASC_HUMAN	Decreases Expression	[7]
Thymocyte selection-associated high mobility group box protein TOX (TOX)	OTE8BL5Z	TOX_HUMAN	Increases Expression	[7]
Glutaminase kidney isoform, mitochondrial (GLS)	OTGOZG2M	GLSK_HUMAN	Increases Expression	[7]
Rho-related BTB domain-containing protein 3 (RHOBTB3)	OT1BFKPH	RHBT3_HUMAN	Increases Expression	[7]
Serine protease 23 (PRSS23)	OT6DQAM1	PRS23_HUMAN	Decreases Expression	[7]
Peripheral-type benzodiazepine receptor-associated protein 1 (TSPOAP1)	OTAM8SGF	RIMB1_HUMAN	Decreases Expression	[7]
Chondroitin sulfate proteoglycan 5 (CSPG5)	OTXFEBWR	CSPG5_HUMAN	Decreases Expression	[7]
Protocadherin-8 (PCDH8)	OTDDOQM2	PCDH8_HUMAN	Increases Expression	[7]
Histone acetyltransferase KAT7 (KAT7)	OTUN98IC	KAT7_HUMAN	Decreases Expression	[7]
Ly6/PLAUR domain-containing protein 3 (LYPD3)	OTLR2PYX	LYPD3_HUMAN	Increases Expression	[7]
Homeobox protein SIX3 (SIX3)	OTP5E3VU	SIX3_HUMAN	Decreases Expression	[7]
Neuroendocrine secretory protein 55 (GNAS)	OTMH8BKJ	GNAS3_HUMAN	Increases Expression	[7]
Claudin-7 (CLDN7)	OTNE0XHQ	CLD7_HUMAN	Increases Expression	[7]
Homeobox protein SIX6 (SIX6)	OTD1RD9D	SIX6_HUMAN	Decreases Expression	[7]
Protein phosphatase 1 regulatory subunit 3D (PPP1R3D)	OTZNC7R2	PPR3D_HUMAN	Increases Expression	[7]
C-X-C motif chemokine 14 (CXCL14)	OTM189TA	CXL14_HUMAN	Increases Expression	[7]
Fibroblast growth factor 19 (FGF19)	OT2DVJWY	FGF19_HUMAN	Increases Expression	[7]
Heat shock 70 kDa protein 4L (HSPA4L)	OT181WZB	HS74L_HUMAN	Increases Expression	[7]
TBC1 domain family member 8 (TBC1D8)	OT2011SS	TBCD8_HUMAN	Decreases Expression	[7]
BAG family molecular chaperone regulator 2 (BAG2)	OTI6LD27	BAG2_HUMAN	Increases Expression	[7]
Claudin-1 (CLDN1)	OT27KV99	CLD1_HUMAN	Increases Expression	[7]
Histone-lysine N-methyltransferase NSD2 (NSD2)	OTQ6SW4R	NSD2_HUMAN	Decreases Expression	[7]
Purine nucleoside phosphorylase (PNP)	OTO5NIJ2	PNPH_HUMAN	Increases Expression	[7]
Urokinase-type plasminogen activator (PLAU)	OTX0QGKK	UROK_HUMAN	Increases Expression	[7]
Tissue-type plasminogen activator (PLAT)	OTQPDNAB	TPA_HUMAN	Increases Expression	[7]
Adenosine deaminase (ADA)	OTOX2872	ADA_HUMAN	Decreases Expression	[7]
Argininosuccinate synthase (ASS1)	OT4ZMG0Q	ASSY_HUMAN	Increases Expression	[7]
Serine protease inhibitor Kazal-type 1 (SPINK1)	OTSUVAL2	ISK1_HUMAN	Increases Expression	[7]
Pro-epidermal growth factor (EGF)	OTANRJ0L	EGF_HUMAN	Decreases Expression	[7]
Proenkephalin-B (PDYN)	OTEJ6430	PDYN_HUMAN	Increases Expression	[7]
Calcitonin (CALCA)	OTZ11LHB	CALC_HUMAN	Increases Expression	[7]
Pro-neuropeptide Y (NPY)	OT4ICV3P	NPY_HUMAN	Increases Expression	[7]
Insulin-like growth factor II (IGF2)	OTJ4O6MW	IGF2_HUMAN	Increases Expression	[7]
Alpha-1-acid glycoprotein 1 (ORM1)	OTZKSBRE	A1AG1_HUMAN	Decreases Expression	[7]
Annexin A1 (ANXA1)	OT5OFDJC	ANXA1_HUMAN	Increases Expression	[7]
Platelet-derived growth factor subunit A (PDGFA)	OTCMZ0W8	PDGFA_HUMAN	Increases Expression	[7]
Ornithine aminotransferase, mitochondrial (OAT)	OTEKO8CT	OAT_HUMAN	Increases Expression	[7]
N-myc proto-oncogene protein (MYCN)	OTWD33K1	MYCN_HUMAN	Increases Expression	[7]
HLA class II histocompatibility antigen gamma chain (CD74)	OTO16X4Q	HG2A_HUMAN	Increases Expression	[7]
Protein S100-B (S100B)	OTHHDS33	S100B_HUMAN	Increases Expression	[7]
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Increases Expression	[7]
Glycophorin-C (GYPC)	OTOEDR7O	GLPC_HUMAN	Increases Expression	[7]
Endothelin-1 (EDN1)	OTZCACEG	EDN1_HUMAN	Increases Expression	[7]
Intercellular adhesion molecule 1 (ICAM1)	OTTOIX77	ICAM1_HUMAN	Increases Expression	[7]
Transcription factor Jun (JUN)	OTCYBO6X	JUN_HUMAN	Increases Expression	[7]
Fatty acid-binding protein, heart (FABP3)	OT562DA1	FABPH_HUMAN	Increases Expression	[7]
Transcription factor AP-2-alpha (TFAP2A)	OTMYT3NK	AP2A_HUMAN	Increases Expression	[7]
Protein kinase C beta type (PRKCB)	OTYQ0656	KPCB_HUMAN	Increases Expression	[7]
Keratin, type I cytoskeletal 18 (KRT18)	OTVLQFIP	K1C18_HUMAN	Increases Expression	[7]
Keratin, type II cytoskeletal 8 (KRT8)	OTTM4X11	K2C8_HUMAN	Increases Expression	[7]
Beta-crystallin A3 (CRYBA1)	OT8617WJ	CRBA1_HUMAN	Decreases Expression	[7]
Collagen alpha-2(V) chain (COL5A2)	OT5VOSQE	CO5A2_HUMAN	Increases Expression	[7]
Protein S100-A6 (S100A6)	OTHHPZQ8	S10A6_HUMAN	Increases Expression	[7]
Neurofilament light polypeptide (NEFL)	OTQESJV4	NFL_HUMAN	Increases Expression	[7]
Neurofilament medium polypeptide (NEFM)	OT8VCBNF	NFM_HUMAN	Increases Expression	[7]
Annexin A2 (ANXA2)	OTFNS0CC	ANXA2_HUMAN	Increases Expression	[7]
Tyrosine-protein kinase Lyn (LYN)	OTP686K2	LYN_HUMAN	Increases Expression	[7]
Collagen alpha-2(I) chain (COL1A2)	OTY7G382	CO1A2_HUMAN	Increases Expression	[7]
Tumor necrosis factor receptor superfamily member 16 (NGFR)	OTPKSM49	TNR16_HUMAN	Increases Expression	[7]
Complement decay-accelerating factor (CD55)	OTZ3HWTO	DAF_HUMAN	Increases Expression	[7]
Asparagine synthetase (ASNS)	OT8R922G	ASNS_HUMAN	Increases Expression	[7]
Retinol-binding protein 1 (RBP1)	OTRP1MFC	RET1_HUMAN	Increases Expression	[7]
Heme oxygenase 1 (HMOX1)	OTC1W6UX	HMOX1_HUMAN	Increases Expression	[7]
Tumor-associated calcium signal transducer 2 (TACSTD2)	OTLSZR00	TACD2_HUMAN	Increases Expression	[7]
Protein FAM200B (FAM200B)	OTQMCR8C	F200B_HUMAN	Decreases Expression	[7]
Apelin receptor early endogenous ligand (APELA)	OTYY0P69	ELA_HUMAN	Increases Expression	[7]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Decreases Expression	[7]
Osteopontin (SPP1)	OTJGC23Y	OSTP_HUMAN	Increases Expression	[7]
COUP transcription factor 1 (NR2F1)	OTGWZWYL	COT1_HUMAN	Increases Expression	[7]
Chromogranin-A (CHGA)	OTXYX5JH	CMGA_HUMAN	Increases Expression	[7]
Tissue factor pathway inhibitor (TFPI)	OTA0FX16	TFPI1_HUMAN	Increases Expression	[7]
Mast/stem cell growth factor receptor Kit (KIT)	OTHUY3VZ	KIT_HUMAN	Increases Expression	[7]
Retinoic acid receptor beta (RARB)	OT367U3E	RARB_HUMAN	Increases Expression	[7]
Thyroid hormone receptor beta (THRB)	OTBBIRHZ	THB_HUMAN	Increases Expression	[7]
Clusterin (CLU)	OTQGG0JM	CLUS_HUMAN	Increases Expression	[7]
Hyaluronan and proteoglycan link protein 1 (HAPLN1)	OTXWR9TJ	HPLN1_HUMAN	Increases Expression	[7]
Microtubule-associated protein 2 (MAP2)	OT6UYT3X	MTAP2_HUMAN	Increases Expression	[7]
Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)	OT2HZK5M	GTR3_HUMAN	Increases Expression	[7]
Serine/threonine-protein kinase pim-1 (PIM1)	OTWEKXTU	PIM1_HUMAN	Increases Expression	[7]
Collagen alpha-1(VI) chain (COL6A1)	OTYKSCOB	CO6A1_HUMAN	Increases Expression	[7]
Collagen alpha-3(VI) chain (COL6A3)	OTAS6R6I	CO6A3_HUMAN	Increases Expression	[7]
Annexin A3 (ANXA3)	OTDD8OI7	ANXA3_HUMAN	Increases Expression	[7]
Bone morphogenetic protein 2 (BMP2)	OT23T37S	BMP2_HUMAN	Increases Expression	[7]
Bone morphogenetic protein 4 (BMP4)	OTPZMDFH	BMP4_HUMAN	Increases Expression	[7]
Cadherin-1 (CDH1)	OTFJMXPM	CADH1_HUMAN	Increases Expression	[7]
Interferon-induced transmembrane protein 1 (IFITM1)	OTECO1G8	IFM1_HUMAN	Increases Expression	[7]
Gamma-interferon-inducible lysosomal thiol reductase (IFI30)	OT9DERT1	GILT_HUMAN	Increases Expression	[7]
Protein Cripto (CRIPTO)	OT46DZXJ	TDGF1_HUMAN	Increases Expression	[7]
Lysosome-associated membrane glycoprotein 2 (LAMP2)	OTLUGEJC	LAMP2_HUMAN	Increases Expression	[7]
Phospholipase A2, membrane associated (PLA2G2A)	OT1NY7BF	PA2GA_HUMAN	Increases Expression	[7]
Pyruvate kinase PKM (PKM)	OTLHHMC2	KPYM_HUMAN	Increases Expression	[7]
Protein C-ets-1 (ETS1)	OT4LVGDN	ETS1_HUMAN	Increases Expression	[7]
Ras-related C3 botulinum toxin substrate 2 (RAC2)	OTAOHFNH	RAC2_HUMAN	Increases Expression	[7]
Prostatic acid phosphatase (ACP3)	OTSIM0YG	PPAP_HUMAN	Increases Expression	[7]
Ezrin (EZR)	OTHBPF1Z	EZRI_HUMAN	Increases Expression	[7]
NAD(P)H dehydrogenase 1 (NQO1)	OTZGGIVK	NQO1_HUMAN	Increases Expression	[7]
CD44 antigen (CD44)	OT9TTJ41	CD44_HUMAN	Increases Expression	[7]
Ribosyldihydronicotinamide dehydrogenase (NQO2)	OTGDAJRZ	NQO2_HUMAN	Increases Expression	[7]
Platelet-derived growth factor receptor alpha (PDGFRA)	OTDJXUCN	PGFRA_HUMAN	Increases Expression	[7]
Solute carrier family 25 member 16 (SLC25A16)	OTTTUL91	GDC_HUMAN	Increases Expression	[7]
Epithelial cell adhesion molecule (EPCAM)	OTHBZK5X	EPCAM_HUMAN	Increases Expression	[7]
Carboxypeptidase E (CPE)	OTXNTV79	CBPE_HUMAN	Increases Expression	[7]
Protein kinase C alpha type (PRKCA)	OT5UWNRD	KPCA_HUMAN	Increases Expression	[7]
Atrial natriuretic peptide receptor 3 (NPR3)	OT6MQP3A	ANPRC_HUMAN	Increases Expression	[7]
cAMP-dependent protein kinase catalytic subunit alpha (PRKACA)	OTAKDCMR	KAPCA_HUMAN	Increases Expression	[7]
CCAAT/enhancer-binding protein beta (CEBPB)	OTM9MQIA	CEBPB_HUMAN	Increases Expression	[7]
Neuromodulin (GAP43)	OT2OTGGV	NEUM_HUMAN	Increases Expression	[7]
Galectin-3 (LGALS3)	OTYQT0ZI	LEG3_HUMAN	Increases Expression	[7]
Insulin-like growth factor-binding protein 3 (IGFBP3)	OTIX63TX	IBP3_HUMAN	Decreases Expression	[7]
Vascular endothelial growth factor receptor 1 (FLT1)	OTT0OGYS	VGFR1_HUMAN	Increases Expression	[7]
Bone morphogenetic protein 7 (BMP7)	OTYATP2K	BMP7_HUMAN	Increases Expression	[7]
Integrin beta-5 (ITGB5)	OT21MF51	ITB5_HUMAN	Decreases Expression	[7]
Pituitary adenylate cyclase-activating polypeptide (ADCYAP1)	OT0LQH93	PACA_HUMAN	Increases Expression	[7]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3)	OTC1UOHP	ATF3_HUMAN	Increases Expression	[7]
Cadherin-2 (CDH2)	OTH0Y56P	CADH2_HUMAN	Decreases Expression	[7]
Hexokinase-1 (HK1)	OTMPHE8O	HXK1_HUMAN	Increases Expression	[7]
Alpha-1-acid glycoprotein 2 (ORM2)	OTRJGZP8	A1AG2_HUMAN	Decreases Expression	[7]
Complement receptor type 2 (CR2)	OT90NDLY	CR2_HUMAN	Increases Expression	[7]
Serine protease inhibitor Kazal-type 2 (SPINK2)	OTSFBT0G	ISK2_HUMAN	Increases Expression	[7]
POU domain, class 3, transcription factor 3 (POU3F3)	OT6BBXPD	PO3F3_HUMAN	Increases Expression	[7]
Muscarinic acetylcholine receptor M3 (CHRM3)	OTKSD095	ACM3_HUMAN	Increases Expression	[7]
Protachykinin-1 (TAC1)	OTM842YW	TKN1_HUMAN	Increases Expression	[7]
Serine/threonine-protein kinase MAK (MAK)	OTEU2G41	MAK_HUMAN	Decreases Expression	[7]
Ephrin-A1 (EFNA1)	OTU2NUA2	EFNA1_HUMAN	Increases Expression	[7]
Neurofibromin (NF1)	OTC29NHH	NF1_HUMAN	Decreases Expression	[7]
Kit ligand (KITLG)	OTB9AVQ4	SCF_HUMAN	Increases Expression	[7]
Diamine acetyltransferase 1 (SAT1)	OT52AU22	SAT1_HUMAN	Increases Expression	[7]
Receptor tyrosine-protein kinase erbB-3 (ERBB3)	OTRSST0A	ERBB3_HUMAN	Increases Expression	[7]
CD9 antigen (CD9)	OT2184XU	CD9_HUMAN	Increases Expression	[7]
Bone morphogenetic protein 5 (BMP5)	OTC0Y6E0	BMP5_HUMAN	Increases Expression	[7]
Alpha-(1,3)-fucosyltransferase 4 (FUT4)	OTIBXRTL	FUT4_HUMAN	Increases Expression	[7]
Cadherin-3 (CDH3)	OTKNLQU7	CADH3_HUMAN	Increases Expression	[7]
Fibroblast growth factor receptor 3 (FGFR3)	OTSAXDIL	FGFR3_HUMAN	Increases Expression	[7]
Calretinin (CALB2)	OTSNMCG9	CALB2_HUMAN	Increases Expression	[7]
Carbonic anhydrase 4 (CA4)	OT3K93LZ	CAH4_HUMAN	Decreases Expression	[7]
Prostaglandin G/H synthase 1 (PTGS1)	OTHCRLEC	PGH1_HUMAN	Decreases Expression	[7]
Peptidyl-prolyl cis-trans isomerase B (PPIB)	OTLPH6KN	PPIB_HUMAN	Increases Expression	[7]
Colorectal mutant cancer protein (MCC)	OTQVI1EM	CRCM_HUMAN	Increases Expression	[7]
Paired box protein Pax-7 (PAX7)	OTDMQRPO	PAX7_HUMAN	Increases Expression	[7]
Paired box protein Pax-3 (PAX3)	OTN5PJZV	PAX3_HUMAN	Increases Expression	[7]
Endothelial transcription factor GATA-2 (GATA2)	OTBP2QQ2	GATA2_HUMAN	Increases Expression	[7]
Trans-acting T-cell-specific transcription factor GATA-3 (GATA3)	OTGP7D5Y	GATA3_HUMAN	Increases Expression	[7]
Laminin subunit alpha-2 (LAMA2)	OTFROQWE	LAMA2_HUMAN	Increases Expression	[7]
COUP transcription factor 2 (NR2F2)	OTJFS67N	COT2_HUMAN	Decreases Expression	[7]
Endothelin receptor type B (EDNRB)	OTLLZV3P	EDNRB_HUMAN	Increases Expression	[7]
Protein kinase C eta type (PRKCH)	OTC498N5	KPCL_HUMAN	Increases Expression	[7]
Signal transducer CD24 (CD24)	OT7CODJ4	CD24_HUMAN	Increases Expression	[7]
Endothelin-1 receptor (EDNRA)	OTK9T5O3	EDNRA_HUMAN	Increases Expression	[7]
Atypical chemokine receptor 3 (ACKR3)	OTA6GA4F	ACKR3_HUMAN	Increases Expression	[7]
Myelin protein P0 (MPZ)	OTAR2YXH	MYP0_HUMAN	Increases Expression	[7]
Rhombotin-2 (LMO2)	OTCC370G	RBTN2_HUMAN	Decreases Expression	[7]
Neuropeptide Y receptor type 1 (NPY1R)	OT5DA9DY	NPY1R_HUMAN	Decreases Expression	[7]
Collagen alpha-3(V) chain (COL5A3)	OTCGC4DM	CO5A3_HUMAN	Increases Expression	[7]
Paired box protein Pax-6 (PAX6)	OTOC9876	PAX6_HUMAN	Decreases Expression	[7]
Protein S100-A4 (S100A4)	OTLRGFSQ	S10A4_HUMAN	Increases Expression	[7]
Threonine--tRNA ligase 1, cytoplasmic (TARS1)	OT0PWST5	SYTC_HUMAN	Increases Expression	[7]
Serum paraoxonase/arylesterase 1 (PON1)	OTD0Z2XO	PON1_HUMAN	Decreases Expression	[7]
Homeobox protein MSX-1 (MSX1)	OT5U41ZP	MSX1_HUMAN	Increases Expression	[7]
Gamma-aminobutyric acid receptor subunit beta-3 (GABRB3)	OT80C3D4	GBRB3_HUMAN	Increases Expression	[7]
Ephrin type-A receptor 3 (EPHA3)	OTZJF3ML	EPHA3_HUMAN	Increases Expression	[7]
Ephrin type-B receptor 2 (EPHB2)	OT8VZ6C5	EPHB2_HUMAN	Decreases Expression	[7]
Cellular retinoic acid-binding protein 2 (CRABP2)	OTY01V9G	RABP2_HUMAN	Increases Expression	[7]
GTP cyclohydrolase 1 feedback regulatory protein (GCHFR)	OTEOT8GI	GFRP_HUMAN	Increases Expression	[7]
Translocator protein (TSPO)	OTSU7ESK	TSPO_HUMAN	Increases Expression	[7]
CAMPATH-1 antigen (CD52)	OT02LDQN	CD52_HUMAN	Increases Expression	[7]
Fibroblast growth factor 9 (FGF9)	OT2SKDGM	FGF9_HUMAN	Decreases Expression	[7]
Syndecan-4 (SDC4)	OTKUVUGZ	SDC4_HUMAN	Increases Expression	[7]
14-3-3 protein sigma (SFN)	OTLJCZ1U	1433S_HUMAN	Increases Expression	[7]
Protein S100-A11 (S100A11)	OTI57KDN	S10AB_HUMAN	Increases Expression	[7]
Neural cell adhesion molecule L1 (L1CAM)	OTNWAQ4Y	L1CAM_HUMAN	Increases Expression	[7]
Gastrin/cholecystokinin type B receptor (CCKBR)	OTQSNXOI	GASR_HUMAN	Decreases Expression	[7]
ETS-related transcription factor Elf-1 (ELF1)	OTV5LKIA	ELF1_HUMAN	Increases Expression	[7]
Intercellular adhesion molecule 3 (ICAM3)	OTTZ5A5D	ICAM3_HUMAN	Increases Expression	[7]
Long-chain-fatty-acid--CoA ligase 1 (ACSL1)	OTB06ESI	ACSL1_HUMAN	Increases Expression	[7]
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (MAN1A1)	OT6LIGJP	MA1A1_HUMAN	Increases Expression	[7]
Carbonic anhydrase-related protein (CA8)	OT9Y8GA8	CAH8_HUMAN	Increases Expression	[7]
Prostaglandin E2 receptor EP4 subtype (PTGER4)	OT2GBV06	PE2R4_HUMAN	Increases Expression	[7]
Thrombospondin-2 (THBS2)	OTXET551	TSP2_HUMAN	Increases Expression	[7]
Homeobox protein MSX-2 (MSX2)	OT1WDKE1	MSX2_HUMAN	Increases Expression	[7]
Fibrillin-1 (FBN1)	OTYCJT63	FBN1_HUMAN	Decreases Expression	[7]
Transcription factor SOX-11 (SOX11)	OT4LG7LA	SOX11_HUMAN	Decreases Expression	[7]
Phosphoglucomutase-1 (PGM1)	OT3VM4JX	PGM1_HUMAN	Increases Expression	[7]
Pigment epithelium-derived factor (SERPINF1)	OTWZH98J	PEDF_HUMAN	Decreases Expression	[7]
Amiloride-sensitive sodium channel subunit alpha (SCNN1A)	OTE2KVZV	SCNNA_HUMAN	Increases Expression	[7]
Transgelin-2 (TAGLN2)	OTUXZGDQ	TAGL2_HUMAN	Increases Expression	[7]
Kappa-type opioid receptor (OPRK1)	OTXCZF4L	OPRK_HUMAN	Decreases Expression	[7]
Transcription factor SOX-3 (SOX3)	OT1CRCOB	SOX3_HUMAN	Decreases Expression	[7]
Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1)	OTNBHULA	PACR_HUMAN	Increases Expression	[7]
ETS domain-containing protein Elk-3 (ELK3)	OTBM9BHT	ELK3_HUMAN	Increases Expression	[7]
Signal transducer and activator of transcription 6 (STAT6)	OTCKMP49	STAT6_HUMAN	Increases Expression	[7]
Glutamate receptor 3 (GRIA3)	OT34CNBR	GRIA3_HUMAN	Decreases Expression	[7]
Leukemia inhibitory factor receptor (LIFR)	OT36W9O5	LIFR_HUMAN	Increases Expression	[7]
C-X-C motif chemokine 5 (CXCL5)	OTZOUPCA	CXCL5_HUMAN	Increases Expression	[7]
Excitatory amino acid transporter 1 (SLC1A3)	OTILR60R	EAA1_HUMAN	Increases Expression	[7]
Netrin receptor DCC (DCC)	OT2C1SHW	DCC_HUMAN	Increases Expression	[7]
Tyrosine-protein kinase SYK (SYK)	OTQID87L	KSYK_HUMAN	Increases Expression	[7]
Lysophosphatidic acid receptor 6 (LPAR6)	OT4BY3W4	LPAR6_HUMAN	Increases Expression	[7]
Transcription factor GATA-4 (GATA4)	OTQHWAZG	GATA4_HUMAN	Decreases Expression	[7]
Peptidyl-prolyl cis-trans isomerase C (PPIC)	OTY5Q42N	PPIC_HUMAN	Increases Expression	[7]
Radiation-inducible immediate-early gene IEX-1 (IER3)	OTZJI5FZ	IEX1_HUMAN	Increases Expression	[7]
Ras GTPase-activating-like protein IQGAP1 (IQGAP1)	OTZRWTGA	IQGA1_HUMAN	Increases Expression	[7]
Cytosolic phospholipase A2 (PLA2G4A)	OTE70SOT	PA24A_HUMAN	Increases Expression	[7]
Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2)	OTAOZIGX	GBRB2_HUMAN	Increases Expression	[7]
Retinaldehyde dehydrogenase 3 (ALDH1A3)	OT1C9NKQ	AL1A3_HUMAN	Increases Expression	[7]
DNA-binding protein inhibitor ID-4 (ID4)	OTPMJ39I	ID4_HUMAN	Increases Expression	[7]
Sodium- and chloride-dependent creatine transporter 1 (SLC6A8)	OT88C8JA	SC6A8_HUMAN	Decreases Expression	[7]
Stromal cell-derived factor 1 (CXCL12)	OT2QX5LL	SDF1_HUMAN	Increases Expression	[7]
Tissue factor pathway inhibitor 2 (TFPI2)	OTZCRWOR	TFPI2_HUMAN	Increases Expression	[7]
Transcription factor SOX-2 (SOX2)	OTFAWCAU	SOX2_HUMAN	Decreases Expression	[7]
Transcription factor SOX-9 (SOX9)	OTVDJFGN	SOX9_HUMAN	Increases Expression	[7]
Potassium voltage-gated channel subfamily C member 1 (KCNC1)	OTW9WF1J	KCNC1_HUMAN	Decreases Expression	[7]
Nuclear receptor-interacting protein 1 (NRIP1)	OTIZOJQV	NRIP1_HUMAN	Increases Expression	[7]
Neuropeptide Y receptor type 2 (NPY2R)	OTEWQJ6B	NPY2R_HUMAN	Decreases Expression	[7]
Protein ERGIC-53 (LMAN1)	OTYHKDEO	LMAN1_HUMAN	Decreases Expression	[7]
Beta-arrestin-1 (ARRB1)	OT2NJS37	ARRB1_HUMAN	Increases Expression	[7]
CCAAT/enhancer-binding protein delta (CEBPD)	OTNBIPMY	CEBPD_HUMAN	Increases Expression	[7]
Selenoprotein P (SELENOP)	OT02B8IR	SEPP1_HUMAN	Increases Expression	[7]
Histamine N-methyltransferase (HNMT)	OT9F303M	HNMT_HUMAN	Increases Expression	[7]
Isocitrate dehydrogenase subunit alpha, mitochondrial (IDH3A)	OT5QQB5L	IDH3A_HUMAN	Increases Expression	[7]
Motor neuron and pancreas homeobox protein 1 (MNX1)	OTXP9FH1	MNX1_HUMAN	Increases Expression	[7]
Homeobox protein MOX-1 (MEOX1)	OTJEMT2D	MEOX1_HUMAN	Increases Expression	[7]
Sulfotransferase 1A2 (SULT1A2)	OT7EJ6LQ	ST1A2_HUMAN	Increases Expression	[7]
Matrix metalloproteinase-14 (MMP14)	OT9C197Z	MMP14_HUMAN	Increases Expression	[7]
Protoporphyrinogen oxidase (PPOX)	OT75GZ3K	PPOX_HUMAN	Decreases Expression	[7]
Serpin B9 (SERPINB9)	OTJ811IF	SPB9_HUMAN	Increases Expression	[7]
LIM/homeobox protein Lhx2 (LHX2)	OTK61NP8	LHX2_HUMAN	Decreases Expression	[7]
ETS translocation variant 1 (ETV1)	OT6PMJIK	ETV1_HUMAN	Decreases Expression	[7]
Amiloride-sensitive sodium channel subunit gamma (SCNN1G)	OTSJYQVQ	SCNNG_HUMAN	Increases Expression	[7]
Probable global transcription activator SNF2L2 (SMARCA2)	OTSGJ8SV	SMCA2_HUMAN	Increases Expression	[7]
Glypican-3 (GPC3)	OTWS8WSW	GPC3_HUMAN	Decreases Expression	[7]
Ephrin-A5 (EFNA5)	OTOH4DRR	EFNA5_HUMAN	Decreases Expression	[7]
Stanniocalcin-1 (STC1)	OTGVVXYF	STC1_HUMAN	Increases Expression	[7]
Homeobox protein GBX-2 (GBX2)	OTW0ZI4D	GBX2_HUMAN	Increases Expression	[7]
Beta-crystallin A4 (CRYBA4)	OTQJ5XGE	CRBA4_HUMAN	Decreases Expression	[7]
Integrin alpha-8 (ITGA8)	OTBH8WFD	ITA8_HUMAN	Increases Expression	[7]
Mitogen-activated protein kinase 10 (MAPK10)	OTC46VX1	MK10_HUMAN	Decreases Expression	[7]
Calcipressin-1 (RCAN1)	OT1MVXC7	RCAN1_HUMAN	Increases Expression	[7]
Monocarboxylate transporter 1 (SLC16A1)	OTW1UTZ7	MOT1_HUMAN	Increases Expression	[7]
Voltage-dependent calcium channel subunit alpha-2/delta-1 (CACNA2D1)	OT5YLZIH	CA2D1_HUMAN	Increases Expression	[7]
Ephrin type-A receptor 4 (EPHA4)	OT3AMK0C	EPHA4_HUMAN	Decreases Expression	[7]
Paired mesoderm homeobox protein 1 (PRRX1)	OTTZK5G8	PRRX1_HUMAN	Increases Expression	[7]
Tyrosine-protein phosphatase non-receptor type 5 (PTPN5)	OT2H1KDK	PTN5_HUMAN	Decreases Expression	[7]
Epithelial membrane protein 1 (EMP1)	OTSZHUHQ	EMP1_HUMAN	Increases Expression	[7]
Fibroblast growth factor 8 (FGF8)	OTFU0IUW	FGF8_HUMAN	Decreases Expression	[7]
Proteinase-activated receptor 2 (F2RL1)	OTMRMJ8N	PAR2_HUMAN	Increases Expression	[7]
Cadherin-8 (CDH8)	OTS3SRZ6	CADH8_HUMAN	Decreases Expression	[7]
Homeobox protein DLX-6 (DLX6)	OT0FIJHY	DLX6_HUMAN	Decreases Expression	[7]
Transcription factor SOX-10 (SOX10)	OTF25ULQ	SOX10_HUMAN	Increases Expression	[7]
Neurotrypsin (PRSS12)	OT1MYL3L	NETR_HUMAN	Increases Expression	[7]
Claudin-6 (CLDN6)	OTEN8ID2	CLD6_HUMAN	Increases Expression	[7]
Transcription factor SOX-8 (SOX8)	OTEJXYZM	SOX8_HUMAN	Increases Expression	[7]
Potassium channel subfamily K member 10 (KCNK10)	OT93GC7V	KCNKA_HUMAN	Decreases Expression	[7]
Inhibin beta E chain (INHBE)	OTOI2NYG	INHBE_HUMAN	Increases Expression	[7]
Myelin proteolipid protein (PLP1)	OT8CM9CX	MYPR_HUMAN	Increases Expression	[7]
Synaptosomal-associated protein 25 (SNAP25)	OTUIQ81Q	SNP25_HUMAN	Increases Expression	[7]
Protein S100-A10 (S100A10)	OTI71243	S10AA_HUMAN	Increases Expression	[7]
Somatostatin (SST)	OTY75GQH	SMS_HUMAN	Increases Expression	[7]
Rho-related GTP-binding protein RhoE (RND3)	OTXMXPIH	RND3_HUMAN	Increases Expression	[7]
Neurocalcin-delta (NCALD)	OTJZ8UEL	NCALD_HUMAN	Decreases Expression	[7]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 (GNG11)	OTHIXBGW	GBG11_HUMAN	Increases Expression	[7]
Rho-related GTP-binding protein RhoB (RHOB)	OTHQFQF7	RHOB_HUMAN	Increases Expression	[7]
Small ribosomal subunit protein eS24 (RPS24)	OTSNKIL5	RS24_HUMAN	Increases Expression	[7]
Large ribosomal subunit protein eL31 (RPL31)	OTV9E1OE	RL31_HUMAN	Decreases Expression	[7]
Iroquois-class homeodomain protein IRX-1 (IRX1)	OT0ZN9EJ	IRX1_HUMAN	Increases Expression	[7]
Iroquois-class homeodomain protein IRX-3 (IRX3)	OTLJ48FG	IRX3_HUMAN	Increases Expression	[7]
Fractalkine (CX3CL1)	OTPLGI0E	X3CL1_HUMAN	Increases Expression	[7]
Reelin (RELN)	OTLKMW1O	RELN_HUMAN	Increases Expression	[7]
ETS-related transcription factor Elf-3 (ELF3)	OTUTLEQO	ELF3_HUMAN	Increases Expression	[7]
Protein delta homolog 1 (DLK1)	OTE1VLNB	DLK1_HUMAN	Decreases Expression	[7]
4-aminobutyrate aminotransferase, mitochondrial (ABAT)	OTXAGR7J	GABT_HUMAN	Increases Expression	[7]
Single-stranded DNA-binding protein 2 (SSBP2)	OTYG1G80	SSBP2_HUMAN	Decreases Expression	[7]
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB)	OTRWGNBF	LACTB_HUMAN	Increases Expression	[7]
Matrix-remodeling-associated protein 7 (MXRA7)	OTVQLYIY	MXRA7_HUMAN	Decreases Expression	[7]
Low-density lipoprotein receptor-related protein 2 (LRP2)	OTZ6W681	LRP2_HUMAN	Decreases Expression	[7]
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PPP2R2B)	OTSFVC82	2ABB_HUMAN	Decreases Expression	[7]
Cyclin-dependent kinase 6 (CDK6)	OTR95N0X	CDK6_HUMAN	Increases Expression	[7]
Norrin (NDP)	OTGDJ4US	NDP_HUMAN	Decreases Expression	[7]
Sorbitol dehydrogenase (SORD)	OTC44CR6	DHSO_HUMAN	Decreases Expression	[7]
Sodium channel protein type 7 subunit alpha (SCN7A)	OTK05PXY	SCN7A_HUMAN	Decreases Expression	[7]
Large neutral amino acids transporter small subunit 1 (SLC7A5)	OT2WPVXD	LAT1_HUMAN	Increases Expression	[7]
ATP-dependent 6-phosphofructokinase, platelet type (PFKP)	OTFP7AA8	PFKAP_HUMAN	Increases Expression	[7]
POU domain, class 5, transcription factor 1 (POU5F1)	OTDHHN7O	PO5F1_HUMAN	Increases Expression	[7]
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1)	OTEUYEW6	ROR1_HUMAN	Increases Expression	[7]
Contactin-2 (CNTN2)	OTQG9W7C	CNTN2_HUMAN	Decreases Expression	[7]
Pro-neuregulin-1, membrane-bound isoform (NRG1)	OTZO6F1X	NRG1_HUMAN	Decreases Expression	[7]
Desmocollin-2 (DSC2)	OTODVH8K	DSC2_HUMAN	Increases Expression	[7]
A-kinase anchor protein 12 (AKAP12)	OTCVRDDX	AKA12_HUMAN	Decreases Expression	[7]
Paired box protein Pax-2 (PAX2)	OTKP1N8F	PAX2_HUMAN	Increases Expression	[7]
Dystonin (DST)	OTHZBM4X	DYST_HUMAN	Decreases Expression	[7]
POU domain, class 3, transcription factor 1 (POU3F1)	OTYARA94	PO3F1_HUMAN	Decreases Expression	[7]
Histone-lysine N-methyltransferase MECOM (MECOM)	OTP983W8	MECOM_HUMAN	Decreases Expression	[7]
Transducin-like enhancer protein 4 (TLE4)	OT4QEH6T	TLE4_HUMAN	Decreases Expression	[7]
Collagen alpha-1(XIV) chain (COL14A1)	OTLNJ13O	COEA1_HUMAN	Increases Expression	[7]
Aldehyde oxidase (AOX1)	OT2FZP6H	AOXA_HUMAN	Decreases Expression	[7]
Myocyte-specific enhancer factor 2C (MEF2C)	OTZGF1Y5	MEF2C_HUMAN	Increases Expression	[7]
Putative POU domain, class 5, transcription factor 1B (POU5F1B)	OT0FKQ51	P5F1B_HUMAN	Increases Expression	[7]
Protein CBFA2T1 (RUNX1T1)	OT30DED5	MTG8_HUMAN	Increases Expression	[7]
Voltage-dependent L-type calcium channel subunit beta-2 (CACNB2)	OT53K8W2	CACB2_HUMAN	Decreases Expression	[7]
3',5'-cyclic-AMP phosphodiesterase 4D (PDE4D)	OT1RWFV0	PDE4D_HUMAN	Increases Expression	[7]
Neuroblast differentiation-associated protein AHNAK (AHNAK)	OT6KH1WG	AHNK_HUMAN	Increases Expression	[7]
Divergent protein kinase domain 1C (DIPK1C)	OT4POSL2	DIK1C_HUMAN	Decreases Expression	[7]
Cingulin-like protein 1 (CGNL1)	OTRE9DGT	CGNL1_HUMAN	Increases Expression	[7]
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3GAL1)	OTFCO8QX	SIA4A_HUMAN	Increases Expression	[7]
Forkhead box protein O1 (FOXO1)	OTPJRB6D	FOXO1_HUMAN	Increases Expression	[7]
Contactin-1 (CNTN1)	OT7RNPEY	CNTN1_HUMAN	Increases Expression	[7]
Forkhead box protein C1 (FOXC1)	OTOWZGYO	FOXC1_HUMAN	Increases Expression	[7]
Glutamate receptor ionotropic, kainate 3 (GRIK3)	OTX6K345	GRIK3_HUMAN	Decreases Expression	[7]
Rho GTPase-activating protein 5 (ARHGAP5)	OTOQELUN	RHG05_HUMAN	Decreases Expression	[7]
Platelet-activating factor acetylhydrolase (PLA2G7)	OT6H6AMO	PAFA_HUMAN	Increases Expression	[7]
Dual specificity protein phosphatase 4 (DUSP4)	OT6WAO12	DUS4_HUMAN	Decreases Expression	[7]
RE1-silencing transcription factor (REST)	OTLL92LQ	REST_HUMAN	Increases Expression	[7]
BMP and activin membrane-bound inhibitor homolog (BAMBI)	OTCEJ8W5	BAMBI_HUMAN	Increases Expression	[7]
Noggin (NOG)	OTGRHHPG	NOGG_HUMAN	Increases Expression	[7]
N-myc-interactor (NMI)	OTYVG3NM	NMI_HUMAN	Increases Expression	[7]
Zinc transporter ZIP6 (SLC39A6)	OTCYF466	S39A6_HUMAN	Decreases Expression	[7]
Frizzled-5 (FZD5)	OTXFFY56	FZD5_HUMAN	Decreases Expression	[7]
Protein phosphatase 1 regulatory subunit 1A (PPP1R1A)	OTGTAGCV	PPR1A_HUMAN	Increases Expression	[7]
Semaphorin-5A (SEMA5A)	OTUOIOJV	SEM5A_HUMAN	Decreases Expression	[7]
Cullin-3 (CUL3)	OTDNOAPM	CUL3_HUMAN	Decreases Expression	[7]
Cadherin-18 (CDH18)	OTC06P9H	CAD18_HUMAN	Increases Expression	[7]
Ras-related protein Rab-31 (RAB31)	OTMLXQZ0	RAB31_HUMAN	Increases Expression	[7]
CD166 antigen (ALCAM)	OTCO4LP7	CD166_HUMAN	Increases Expression	[7]
Laminin subunit gamma-2 (LAMC2)	OTJMTM72	LAMC2_HUMAN	Increases Expression	[7]
Runt-related transcription factor 3 (RUNX3)	OTITK1XD	RUNX3_HUMAN	Increases Expression	[7]
Integrin alpha-9 (ITGA9)	OTHN1IKA	ITA9_HUMAN	Increases Expression	[7]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2)	OTTUU92F	ENPP2_HUMAN	Increases Expression	[7]
Krueppel-like factor 5 (KLF5)	OT1ABI9N	KLF5_HUMAN	Increases Expression	[7]
Collagen alpha-3(IX) chain (COL9A3)	OTCUJOEK	CO9A3_HUMAN	Increases Expression	[7]
Ras-related protein Rab-33A (RAB33A)	OTHHU6WA	RB33A_HUMAN	Decreases Expression	[7]
Septin-6 (SEPTIN6)	OTIV9RTK	SEPT6_HUMAN	Increases Expression	[7]
Tripartite motif-containing protein 14 (TRIM14)	OTLQKUG0	TRI14_HUMAN	Increases Expression	[7]
Transcription factor E2F2 (E2F2)	OTO75RM7	E2F2_HUMAN	Decreases Expression	[7]
Frizzled-2 (FZD2)	OT952ML1	FZD2_HUMAN	Decreases Expression	[7]
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (PDE3A)	OTKUW1WT	PDE3A_HUMAN	Increases Expression	[7]
Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3)	OT7M67WT	GALT3_HUMAN	Increases Expression	[7]
Protein disulfide-isomerase A5 (PDIA5)	OT76ZSX5	PDIA5_HUMAN	Increases Expression	[7]
Inositol 1,4,5-trisphosphate receptor type 2 (ITPR2)	OTPHGZ19	ITPR2_HUMAN	Increases Expression	[7]
Caspase-8 (CASP8)	OTA8TVI8	CASP8_HUMAN	Increases Expression	[7]
Metabotropic glutamate receptor 3 (GRM3)	OTJFGE9S	GRM3_HUMAN	Decreases Expression	[7]
AT-rich interactive domain-containing protein 5B (ARID5B)	OTUQ4CQY	ARI5B_HUMAN	Increases Expression	[7]
Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4)	OTTDCUAO	NFAC4_HUMAN	Decreases Expression	[7]
Opioid-binding protein/cell adhesion molecule (OPCML)	OT93PQ6Y	OPCM_HUMAN	Increases Expression	[7]
Uncharacterized protein KIAA0040 (KIAA0040)	OT27EBY3	K0040_HUMAN	Increases Expression	[7]
Ras GTPase-activating protein 2 (RASA2)	OTL06RG2	RASA2_HUMAN	Decreases Expression	[7]
Ankyrin repeat domain-containing protein 1 (ANKRD1)	OTHJ7JV9	ANKR1_HUMAN	Increases Expression	[7]
Ephrin type-A receptor 7 (EPHA7)	OT3VC211	EPHA7_HUMAN	Increases Expression	[7]
Angiopoietin-1 (ANGPT1)	OTVZ1NG3	ANGP1_HUMAN	Increases Expression	[7]
Ryanodine receptor 3 (RYR3)	OT4EHIP4	RYR3_HUMAN	Decreases Expression	[7]
SH2 domain-containing adapter protein B (SHB)	OTF2HSC0	SHB_HUMAN	Increases Expression	[7]
Homeobox protein SIX1 (SIX1)	OT70YYWM	SIX1_HUMAN	Increases Expression	[7]
ALX homeobox protein 1 (ALX1)	OTZVARA5	ALX1_HUMAN	Increases Expression	[7]
Myosin light chain kinase, smooth muscle (MYLK)	OT78QB4A	MYLK_HUMAN	Decreases Expression	[7]
Metallophosphoesterase MPPED2 (MPPED2)	OT7XLMJ6	MPPD2_HUMAN	Decreases Expression	[7]
Mothers against decapentaplegic homolog 2 (SMAD2)	OTC6VB4K	SMAD2_HUMAN	Decreases Expression	[7]
Nuclear factor erythroid 2-related factor 2 (NFE2L2)	OT0HENJ5	NF2L2_HUMAN	Increases Expression	[7]
Insulin-like growth factor-binding protein 7 (IGFBP7)	OT1D416P	IBP7_HUMAN	Increases Expression	[7]
Laminin subunit alpha-4 (LAMA4)	OTHI7TA0	LAMA4_HUMAN	Increases Expression	[7]
Exostosin-1 (EXT1)	OTRPALJK	EXT1_HUMAN	Decreases Expression	[7]
Cyclin-G2 (CCNG2)	OTII38K2	CCNG2_HUMAN	Decreases Expression	[7]
Prostasin (PRSS8)	OT5KLL35	PRSS8_HUMAN	Increases Expression	[7]
Gamma-interferon-inducible protein 16 (IFI16)	OT4SPU0U	IF16_HUMAN	Increases Expression	[7]
Melanoma-derived growth regulatory protein (MIA)	OTG5FN5S	MIA_HUMAN	Increases Expression	[7]
Cytochrome P450 1B1 (CYP1B1)	OTYXFLSD	CP1B1_HUMAN	Increases Expression	[7]
Dual specificity protein phosphatase 5 (DUSP5)	OTH96RA7	DUS5_HUMAN	Increases Expression	[7]
NADP-dependent malic enzyme, mitochondrial (ME3)	OT3XMLYG	MAON_HUMAN	Decreases Expression	[7]
Reticulon-1 (RTN1)	OTCX1SMK	RTN1_HUMAN	Decreases Expression	[7]
Receptor-type tyrosine-protein phosphatase O (PTPRO)	OTFLKWOY	PTPRO_HUMAN	Decreases Expression	[7]
Tumor protein D53 (TPD52L1)	OTSA6U0I	TPD53_HUMAN	Increases Expression	[7]
Protein inscuteable homolog (INSC)	OTP16ERR	INSC_HUMAN	Increases Expression	[7]
Inverted formin-2 (INF2)	OT8ZM13C	INF2_HUMAN	Increases Expression	[7]
MHC class I polypeptide-related sequence B (MICB)	OTS2DVDW	MICB_HUMAN	Increases Expression	[7]
Centrosomal protein kizuna (KIZ)	OT5VCKSM	KIZ_HUMAN	Decreases Expression	[7]
UPF0561 protein C2orf68 (C2ORF68)	OTNNFK6R	CB068_HUMAN	Decreases Expression	[7]
FH1/FH2 domain-containing protein 3 (FHOD3)	OT1WUBQX	FHOD3_HUMAN	Decreases Expression	[7]
Complement component receptor 1-like protein (CR1L)	OTX3KR7U	CR1L_HUMAN	Increases Expression	[7]
Transcription factor RFX4 (RFX4)	OTYFRHPA	RFX4_HUMAN	Increases Expression	[7]
Cell cycle control protein 50B (TMEM30B)	OTNSBH84	CC50B_HUMAN	Increases Expression	[7]
Transcription factor Sp6 (SP6)	OTRAB1PN	SP6_HUMAN	Increases Expression	[7]
Mitochondrial 10-formyltetrahydrofolate dehydrogenase (ALDH1L2)	OTCH86VF	AL1L2_HUMAN	Increases Expression	[7]
Synaptic vesicle glycoprotein 2C (SV2C)	OTIH108W	SV2C_HUMAN	Increases Expression	[7]
Uncharacterized protein C8orf34 (C8ORF34)	OTXCTHDG	CH034_HUMAN	Increases Expression	[7]
Cell adhesion molecule-related/down-regulated by oncogenes (CDON)	OT81X593	CDON_HUMAN	Increases Expression	[7]
Extracellular tyrosine-protein kinase PKDCC (PKDCC)	OTVXJR26	PKDCC_HUMAN	Increases Expression	[7]
Raftlin-2 (RFTN2)	OT4WYAD9	RFTN2_HUMAN	Increases Expression	[7]
Seizure protein 6 homolog (SEZ6)	OTCD8K5D	SEZ6_HUMAN	Increases Expression	[7]
Acyl-coenzyme A synthetase ACSM3, mitochondrial (ACSM3)	OT0AE1IV	ACSM3_HUMAN	Increases Expression	[7]
Pleckstrin homology-like domain family A member 2 (PHLDA2)	OTMV9DPP	PHLA2_HUMAN	Increases Expression	[7]
Rho GTPase-activating protein 15 (ARHGAP15)	OT9CKHDC	RHG15_HUMAN	Decreases Expression	[7]
Fibulin-7 (FBLN7)	OT1XRDP6	FBLN7_HUMAN	Decreases Expression	[7]
Cordon-bleu protein-like 1 (COBLL1)	OTQFN1TC	COBL1_HUMAN	Increases Expression	[7]
Protein Largen (PRR16)	OTG4TEGR	LARGN_HUMAN	Increases Expression	[7]
TPA-induced transmembrane protein (C3ORF52)	OTI0JAT8	TTMP_HUMAN	Increases Expression	[7]
FRAS1-related extracellular matrix protein 1 (FREM1)	OTMHRV87	FREM1_HUMAN	Increases Expression	[7]
Solute carrier family 25 member 53 (SLC25A53)	OTNHVTOB	S2553_HUMAN	Decreases Expression	[7]
Protein BEX5 (BEX5)	OTZ2RB6L	BEX5_HUMAN	Increases Expression	[7]
Protein phosphatase 1J (PPM1J)	OTM6GDJJ	PPM1J_HUMAN	Increases Expression	[7]
Uncharacterized protein KIAA1755 (KIAA1755)	OT1FCGEW	K1755_HUMAN	Increases Expression	[7]
Collectin-12 (COLEC12)	OTIQTK9G	COL12_HUMAN	Increases Expression	[7]
EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT)	OT4A2A8P	EOGT_HUMAN	Increases Expression	[7]
Neurite extension and migration factor (NEXMIF)	OT576F40	NEXMI_HUMAN	Decreases Expression	[7]
Uncharacterized protein C6orf141 (C6ORF141)	OTUS3SIQ	CF141_HUMAN	Decreases Expression	[7]
Centrosomal protein of 85 kDa-like (CEP85L)	OTSHJFOT	CE85L_HUMAN	Increases Expression	[7]
Transmembrane protein 170B (TMEM170B)	OT4AS8RJ	T170B_HUMAN	Decreases Expression	[7]
Protein FAM162B (FAM162B)	OTZ31RP5	F162B_HUMAN	Increases Expression	[7]
LINE-1 type transposase domain-containing protein 1 (L1TD1)	OTB2W20Y	LITD1_HUMAN	Increases Expression	[7]
KN motif and ankyrin repeat domain-containing protein 4 (KANK4)	OT5WC0Q8	KANK4_HUMAN	Increases Expression	[7]
Transcription factor HES-5 (HES5)	OTW7JEHV	HES5_HUMAN	Decreases Expression	[7]
PX domain-containing protein 1 (PXDC1)	OTQUA3TG	PXDC1_HUMAN	Increases Expression	[7]
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3)	OTGQV0CU	BIG3_HUMAN	Decreases Expression	[7]
Glycoprotein endo-alpha-1,2-mannosidase-like protein (MANEAL)	OT248IN0	MANEL_HUMAN	Increases Expression	[7]
G kinase-anchoring protein 1 (GKAP1)	OTHZRJ56	GKAP1_HUMAN	Decreases Expression	[7]
Myomegalin (PDE4DIP)	OTS15WNF	MYOME_HUMAN	Increases Expression	[7]
Uncharacterized protein C1orf53 (C1ORF53)	OTQTOA4D	CA053_HUMAN	Decreases Expression	[7]
Scm-like with four MBT domains protein 2 (SFMBT2)	OTZQT61Q	SMBT2_HUMAN	Increases Expression	[7]
DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2)	OTLEF5TY	DC122_HUMAN	Decreases Expression	[7]
Proteasome adapter and scaffold protein ECM29 (ECPAS)	OT1C0KOI	ECM29_HUMAN	Decreases Expression	[7]
B box and SPRY domain-containing protein (BSPRY)	OTVVZRKY	BSPRY_HUMAN	Increases Expression	[7]
Meteorin-like protein (METRNL)	OTB0DDL0	METRL_HUMAN	Increases Expression	[7]
Metalloreductase STEAP3 (STEAP3)	OTS9GZK5	STEA3_HUMAN	Increases Expression	[7]
E3 ubiquitin-protein ligase RNF43 (RNF43)	OT2R9YDP	RNF43_HUMAN	Increases Expression	[7]
LIM/homeobox protein Lhx8 (LHX8)	OT0DFL7C	LHX8_HUMAN	Increases Expression	[7]
Transcription factor Sp5 (SP5)	OT4HUP9B	SP5_HUMAN	Increases Expression	[7]
Tyrosine-protein kinase STYK1 (STYK1)	OT61CSU7	STYK1_HUMAN	Increases Expression	[7]
Volume-regulated anion channel subunit LRRC8E (LRRC8E)	OTUZTANF	LRC8E_HUMAN	Increases Expression	[7]
MFS-type transporter SLC18B1 (SLC18B1)	OT9EVUN1	S18B1_HUMAN	Increases Expression	[7]
TMF-regulated nuclear protein 1 (TRNP1)	OTYYV8LN	TRNP1_HUMAN	Increases Expression	[7]
Epithelial splicing regulatory protein 1 (ESRP1)	OTNCS4SL	ESRP1_HUMAN	Increases Expression	[7]
Cdc42 effector protein 5 (CDC42EP5)	OTQQDUCD	BORG3_HUMAN	Increases Expression	[7]
Protein C3orf33 (C3ORF33)	OTP8MJAN	CC033_HUMAN	Decreases Expression	[7]
DENN domain-containing protein 1B (DENND1B)	OT3VCNPE	DEN1B_HUMAN	Decreases Expression	[7]
Phospholipase B-like 1 (PLBD1)	OTHYEB4W	PLBL1_HUMAN	Increases Expression	[7]
Polypeptide N-acetylgalactosaminyltransferase 18 (GALNT18)	OTKIIELC	GLT18_HUMAN	Increases Expression	[7]
Volume-regulated anion channel subunit LRRC8B (LRRC8B)	OTH2LMJ4	LRC8B_HUMAN	Decreases Expression	[7]
Transmembrane protein 154 (TMEM154)	OTEAFLJE	TM154_HUMAN	Increases Expression	[7]
Transmembrane protein 88 (TMEM88)	OTA96YEL	TMM88_HUMAN	Decreases Expression	[7]
Interleukin-27 receptor subunit alpha (IL27RA)	OTSQBAKI	I27RA_HUMAN	Increases Expression	[7]
Lactase-like protein (LCTL)	OTN36T21	LCTL_HUMAN	Decreases Expression	[7]
Layilin (LAYN)	OT9A9Q1X	LAYN_HUMAN	Increases Expression	[7]
ALK and LTK ligand 2 (ALKAL2)	OTTLHL64	ALKL2_HUMAN	Increases Expression	[7]
Inactive serine protease PAMR1 (PAMR1)	OT83ZH5U	PAMR1_HUMAN	Decreases Expression	[7]
Nephronectin (NPNT)	OTFZAO1G	NPNT_HUMAN	Increases Expression	[7]
Interleukin-20 receptor subunit beta (IL20RB)	OTHFXK95	I20RB_HUMAN	Increases Expression	[7]
R-spondin-2 (RSPO2)	OT3HHXU0	RSPO2_HUMAN	Decreases Expression	[7]
Transmembrane channel-like protein 5 (TMC5)	OTO5D86M	TMC5_HUMAN	Increases Expression	[7]
Transmembrane protein 64 (TMEM64)	OTO9IDFD	TMM64_HUMAN	Increases Expression	[7]
Nesprin-3 (SYNE3)	OTEOJBYB	SYNE3_HUMAN	Increases Expression	[7]
Metastasis-associated in colon cancer protein 1 (MACC1)	OTV3DLX0	MACC1_HUMAN	Increases Expression	[7]
Zinc finger protein basonuclin-2 (BNC2)	OTU22H9Z	BNC2_HUMAN	Increases Expression	[7]
Lysophospholipid acyltransferase 1 (MBOAT1)	OT4XR6TE	MBOA1_HUMAN	Increases Expression	[7]
FYVE, RhoGEF and PH domain-containing protein 5 (FGD5)	OT5VIRP2	FGD5_HUMAN	Increases Expression	[7]
Solute carrier organic anion transporter family member 4C1 (SLCO4C1)	OTVILUUN	SO4C1_HUMAN	Increases Expression	[7]
RNA-binding protein with multiple splicing 2 (RBPMS2)	OTY24L1F	RBPS2_HUMAN	Increases Expression	[7]
Leucine-rich repeat-containing protein 55 (LRRC55)	OT8LQI1W	LRC55_HUMAN	Decreases Expression	[7]
RNA-binding protein 43 (RBM43)	OTANIFBG	RBM43_HUMAN	Increases Expression	[7]
Acyl-CoA dehydrogenase family member 11 (ACAD11)	OT3T9HAX	ACD11_HUMAN	Increases Expression	[7]
BTB/POZ domain-containing protein KCTD1 (KCTD1)	OT89U5MB	KCTD1_HUMAN	Increases Expression	[7]
Mediator of RNA polymerase II transcription subunit 13-like (MED13L)	OTSP1W0F	MD13L_HUMAN	Increases Expression	[7]
Eukaryotic translation initiation factor 3 subunit M (EIF3M)	OTVWEV60	EIF3M_HUMAN	Decreases Expression	[7]
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (LINGO2)	OT3N88Q1	LIGO2_HUMAN	Increases Expression	[7]
CXXC-type zinc finger protein 5 (CXXC5)	OTGCN3B5	CXXC5_HUMAN	Increases Expression	[7]
Carbohydrate sulfotransferase 15 (CHST15)	OTNTM2SP	CHSTF_HUMAN	Increases Expression	[7]
Monocarboxylate transporter 14 (SLC16A14)	OTUGDEUV	MOT14_HUMAN	Decreases Expression	[7]
C-myc promoter-binding protein (DENND4A)	OT8FFZ29	MYCPP_HUMAN	Increases Expression	[7]
E3 ubiquitin-protein ligase RNF144B (RNF144B)	OTN7FCDE	R144B_HUMAN	Increases Expression	[7]
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein (BNIPL)	OTDHOA74	BNIPL_HUMAN	Increases Expression	[7]
Cilia- and flagella-associated protein 91 (CFAP91)	OTVDRDGX	CFA91_HUMAN	Decreases Expression	[7]
Transmembrane protein 144 (TMEM144)	OT66EYSR	TM144_HUMAN	Increases Expression	[7]
Uncharacterized protein C11orf96 (C11ORF96)	OTEQU0V7	CK096_HUMAN	Increases Expression	[7]
Amphoterin-induced protein 2 (AMIGO2)	OTPAIT1O	AMGO2_HUMAN	Increases Expression	[7]
Armadillo-like helical domain-containing protein 4 (ARMH4)	OT25GBJM	ARMD4_HUMAN	Decreases Expression	[7]
Sodium/hydrogen exchanger 9B2 (SLC9B2)	OTZVOY8T	SL9B2_HUMAN	Decreases Expression	[7]
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (MAGI2)	OTXDDKZS	MAGI2_HUMAN	Increases Expression	[7]
Regulating synaptic membrane exocytosis protein 1 (RIMS1)	OT10T7CK	RIMS1_HUMAN	Increases Expression	[7]
Inter-alpha-trypsin inhibitor heavy chain H5 (ITIH5)	OTP46PZM	ITIH5_HUMAN	Increases Expression	[7]
Protein FAM124A (FAM124A)	OTF1DJX0	F124A_HUMAN	Decreases Expression	[7]
Glucocorticoid-induced transcript 1 protein (GLCCI1)	OTU0R1CU	GLCI1_HUMAN	Decreases Expression	[7]
Four-jointed box protein 1 (FJX1)	OT8SVTSS	FJX1_HUMAN	Decreases Expression	[7]
Catechol O-methyltransferase domain-containing protein 1 (COMTD1)	OTLQJTBI	CMTD1_HUMAN	Increases Expression	[7]
SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)	OTHH06X8	SESD1_HUMAN	Decreases Expression	[7]
Juxtaposed with another zinc finger protein 1 (JAZF1)	OTXTYSYD	JAZF1_HUMAN	Increases Expression	[7]
Myotubularin-related protein 13 (SBF2)	OTBB8NO8	MTMRD_HUMAN	Increases Expression	[7]
Ras association domain-containing protein 3 (RASSF3)	OT4V9SRK	RASF3_HUMAN	Increases Expression	[7]
E3 ubiquitin-protein ligase TRIM69 (TRIM69)	OTTEGTRD	TRI69_HUMAN	Increases Expression	[7]
Probable D-lactate dehydrogenase, mitochondrial (LDHD)	OTTKLJWP	LDHD_HUMAN	Increases Expression	[7]
Chondroitin sulfate synthase 1 (CHSY1)	OTB1XSSF	CHSS1_HUMAN	Increases Expression	[7]
Dynein regulatory complex protein 11 (IQCA1)	OTFBF3FI	DRC11_HUMAN	Increases Expression	[7]
Protein phosphatase 1 regulatory subunit 3B (PPP1R3B)	OTVCRXEZ	PPR3B_HUMAN	Increases Expression	[7]
Collagen alpha-1(XXIII) chain (COL23A1)	OTYE0N3I	CONA1_HUMAN	Increases Expression	[7]
Testis development-related protein (TDRP)	OTEFLMGF	TDRP_HUMAN	Increases Expression	[7]
Podoplanin (PDPN)	OTBUV19I	PDPN_HUMAN	Increases Expression	[7]
Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPARGC1B)	OTN6FKCB	PRGC2_HUMAN	Increases Expression	[7]
Rab11 family-interacting protein 4 (RAB11FIP4)	OTIGHER7	RFIP4_HUMAN	Increases Expression	[7]
Inactive tyrosine-protein kinase PRAG1 (PRAG1)	OTV83SGI	PRAG1_HUMAN	Increases Expression	[7]
Purine nucleoside phosphorylase LACC1 (LACC1)	OT4SBHI8	LACC1_HUMAN	Increases Expression	[7]
LysM and putative peptidoglycan-binding domain-containing protein 2 (LYSMD2)	OT1VCC2M	LYSM2_HUMAN	Increases Expression	[7]
Proline-rich protein 15 (PRR15)	OTJHSY8G	PRR15_HUMAN	Increases Expression	[7]
Neuron navigator 3 (NAV3)	OT97M1TR	NAV3_HUMAN	Increases Expression	[7]
Immunoglobulin superfamily DCC subclass member 3 (IGDCC3)	OTGR1KA4	IGDC3_HUMAN	Increases Expression	[7]
Sodium channel subunit beta-4 (SCN4B)	OT3JSUWO	SCN4B_HUMAN	Increases Expression	[7]
Sphingosine-1-phosphate phosphatase 2 (SGPP2)	OTIDIJCR	SGPP2_HUMAN	Increases Expression	[7]
Uncharacterized protein C12orf56 (C12ORF56)	OT4KDTKF	CL056_HUMAN	Increases Expression	[7]
Solute carrier family 35 member F2 (SLC35F2)	OTSAD4EQ	S35F2_HUMAN	Increases Expression	[7]
Transcription factor Sp8 (SP8)	OTLCMPKH	SP8_HUMAN	Decreases Expression	[7]
Procollagen galactosyltransferase 2 (COLGALT2)	OTV9EDZB	GT252_HUMAN	Decreases Expression	[7]
Ras and EF-hand domain-containing protein (RASEF)	OTGSAM2E	RASEF_HUMAN	Increases Expression	[7]
Myocardin (MYOCD)	OTSJNHTH	MYCD_HUMAN	Increases Expression	[7]
Protein SIX6OS1 (C14ORF39)	OTFKQ6HO	S6OS1_HUMAN	Decreases Expression	[7]
Neuroligin-1 (NLGN1)	OTGHRRFQ	NLGN1_HUMAN	Decreases Expression	[7]
Protein FAM43A (FAM43A)	OT5RPQRE	FA43A_HUMAN	Increases Expression	[7]
Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1L)	OTVLWW9T	GPD1L_HUMAN	Increases Expression	[7]
ELMO domain-containing protein 1 (ELMOD1)	OT0WRVJC	ELMD1_HUMAN	Increases Expression	[7]
Mucin-15 (MUC15)	OT3PQT6L	MUC15_HUMAN	Increases Expression	[7]
Rho GTPase-activating protein 18 (ARHGAP18)	OTYMJP6H	RHG18_HUMAN	Increases Expression	[7]
MICAL-like protein 1 (MICALL1)	OTHG9B2U	MILK1_HUMAN	Increases Expression	[7]
Protein phosphatase Mn(2+)-dependent 1K (PPM1K)	OTNZ4N4E	PPM1K_HUMAN	Increases Expression	[7]
Thioredoxin domain-containing protein 3 (NME8)	OT4RULP5	TXND3_HUMAN	Increases Expression	[7]
Inactive carboxypeptidase-like protein X2 (CPXM2)	OTDJNOTR	CPXM2_HUMAN	Increases Expression	[7]
Secreted frizzled-related protein 1 (SFRP1)	OT0U9G41	SFRP1_HUMAN	Decreases Expression	[7]
Protein limb expression 1 homolog (LIX1)	OT1CPNCC	LIX1_HUMAN	Decreases Expression	[7]
RING finger protein 175 (RNF175)	OTKAZ8ZW	RN175_HUMAN	Decreases Expression	[7]
Reprimo-like protein (RPRML)	OTPOESFN	RPRML_HUMAN	Increases Expression	[7]
Serine/threonine-protein kinase DCLK2 (DCLK2)	OTT0AU1C	DCLK2_HUMAN	Decreases Expression	[7]
Ephexin-1 (NGEF)	OT9QUXJ3	NGEF_HUMAN	Increases Expression	[7]
Eukaryotic translation initiation factor 4E type 3 (EIF4E3)	OTTWVS2R	IF4E3_HUMAN	Decreases Expression	[7]
E3 ubiquitin-protein ligase RNF182 (RNF182)	OT08FLHZ	RN182_HUMAN	Decreases Expression	[7]
CUGBP Elav-like family member 5 (CELF5)	OT02OG9N	CELF5_HUMAN	Decreases Expression	[7]
Protocadherin-20 (PCDH20)	OTFSNRXK	PCD20_HUMAN	Increases Expression	[7]
Leucine-rich repeat-containing protein 17 (LRRC17)	OT3NZSX3	LRC17_HUMAN	Increases Expression	[7]
APC membrane recruitment protein 2 (AMER2)	OTA1Q07C	AMER2_HUMAN	Increases Expression	[7]
BMP-binding endothelial regulator protein (BMPER)	OTBYON4H	BMPER_HUMAN	Increases Expression	[7]
V-type proton ATPase subunit d 2 (ATP6V0D2)	OTMOZJO0	VA0D2_HUMAN	Increases Expression	[7]
Tetratricopeptide repeat protein 29 (TTC29)	OT37KCUL	TTC29_HUMAN	Increases Expression	[7]
Fibronectin type III domain-containing protein 5 (FNDC5)	OT5CSK9X	FNDC5_HUMAN	Decreases Expression	[7]
Transmembrane protein 178A (TMEM178A)	OTQZY4NP	T178A_HUMAN	Decreases Expression	[7]
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH)	OTBIN5IP	SCPDL_HUMAN	Decreases Expression	[7]
Carbohydrate sulfotransferase 4 (CHST4)	OTESMIW5	CHST4_HUMAN	Increases Expression	[7]
Potassium voltage-gated channel subfamily H member 5 (KCNH5)	OTVAHEAQ	KCNH5_HUMAN	Decreases Expression	[7]
Protein FAM13C (FAM13C)	OTVAGUOV	FA13C_HUMAN	Increases Expression	[7]
Zinc finger protein GLIS3 (GLIS3)	OTBC960E	GLIS3_HUMAN	Decreases Expression	[7]
Neuron navigator 1 (NAV1)	OT667KTL	NAV1_HUMAN	Decreases Expression	[7]
Nesprin-1 (SYNE1)	OTSBSLUH	SYNE1_HUMAN	Increases Expression	[7]
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 (B3GNT7)	OT8UTTXF	B3GN7_HUMAN	Increases Expression	[7]
Interleukin-17 receptor D (IL17RD)	OTKD9XST	I17RD_HUMAN	Decreases Expression	[7]
Bestrophin-4 (BEST4)	OT6S406I	BEST4_HUMAN	Decreases Expression	[7]
Semaphorin-6D (SEMA6D)	OTU0UAZS	SEM6D_HUMAN	Decreases Expression	[7]
Cell adhesion molecule 4 (CADM4)	OT0TFMFE	CADM4_HUMAN	Decreases Expression	[7]
Nuclear receptor coactivator 7 (NCOA7)	OT2CNBOG	NCOA7_HUMAN	Decreases Expression	[7]
LIM domain only protein 3 (LMO3)	OTR7AJHN	LMO3_HUMAN	Decreases Expression	[7]
Fibroblast growth factor-binding protein 3 (FGFBP3)	OTWM1KCM	FGFP3_HUMAN	Increases Expression	[7]
DEP domain-containing mTOR-interacting protein (DEPTOR)	OTCBP1BT	DPTOR_HUMAN	Increases Expression	[7]
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (HMGCLL1)	OT9SQ5PU	HMGC2_HUMAN	Decreases Expression	[7]
E3 ubiquitin-protein ligase LNX (LNX1)	OTZWFMAZ	LNX1_HUMAN	Increases Expression	[7]
Synaptoporin (SYNPR)	OTNCJ9L0	SYNPR_HUMAN	Increases Expression	[7]
Fez family zinc finger protein 2 (FEZF2)	OTU4TXIW	FEZF2_HUMAN	Decreases Expression	[7]
Transmembrane protein 163 (TMEM163)	OTCT1Y1L	TM163_HUMAN	Decreases Expression	[7]
E3 ubiquitin-protein ligase RNF217 (RNF217)	OTAX91ES	RN217_HUMAN	Increases Expression	[7]
Fibronectin type 3 and ankyrin repeat domains protein 1 (FANK1)	OT5641YJ	FANK1_HUMAN	Decreases Expression	[7]
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1)	OTUTPVA9	PREX1_HUMAN	Increases Expression	[7]
Mucolipin-3 (MCOLN3)	OTCRPRVS	MCLN3_HUMAN	Increases Expression	[7]
Protocadherin Fat 3 (FAT3)	OT3C6H8W	FAT3_HUMAN	Decreases Expression	[7]
A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAMTS15)	OTYB6JS3	ATS15_HUMAN	Increases Expression	[7]
A disintegrin and metalloproteinase with thrombospondin motifs 19 (ADAMTS19)	OTEG5Q2G	ATS19_HUMAN	Increases Expression	[7]
Grainyhead-like protein 3 homolog (GRHL3)	OT1V4ZEH	GRHL3_HUMAN	Increases Expression	[7]
Actin filament-associated protein 1-like 1 (AFAP1L1)	OTWNTNDB	AF1L1_HUMAN	Increases Expression	[7]
DENN domain-containing protein 1A (DENND1A)	OTONDAA0	DEN1A_HUMAN	Decreases Expression	[7]
Serine/threonine-protein kinase 32A (STK32A)	OTONYLYO	ST32A_HUMAN	Decreases Expression	[7]
RelA-associated inhibitor (PPP1R13L)	OTNCPLWE	IASPP_HUMAN	Increases Expression	[7]
Protein prune homolog 2 (PRUNE2)	OTGW2974	PRUN2_HUMAN	Decreases Expression	[7]
DEP domain-containing protein 1B (DEPDC1B)	OTMVFOT1	DEP1B_HUMAN	Decreases Expression	[7]
DDB1- and CUL4-associated factor 4 (DCAF4)	OTQU0EUO	DCAF4_HUMAN	Increases Expression	[7]
Pleckstrin homology-like domain family A member 1 (PHLDA1)	OTFTWMIQ	PHLA1_HUMAN	Increases Expression	[7]
PH-interacting protein (PHIP)	OTZY806Z	PHIP_HUMAN	Decreases Expression	[7]
Cholesterol transporter ABCA5 (ABCA5)	OT4B9D92	ABCA5_HUMAN	Decreases Expression	[7]
Secretogranin-3 (SCG3)	OTUYSV2S	SCG3_HUMAN	Increases Expression	[7]
Adhesion G-protein coupled receptor V1 (ADGRV1)	OTLVXHHP	AGRV1_HUMAN	Decreases Expression	[7]
Connector enhancer of kinase suppressor of ras 2 (CNKSR2)	OTAGERJ2	CNKR2_HUMAN	Decreases Expression	[7]
BRI3-binding protein (BRI3BP)	OTWCFPRM	BRI3B_HUMAN	Increases Expression	[7]
Nanos homolog 1 (NANOS1)	OT3UNZZY	NANO1_HUMAN	Decreases Expression	[7]
E3 ubiquitin-protein ligase MYLIP (MYLIP)	OTL0PFGV	MYLIP_HUMAN	Increases Expression	[7]
Jun dimerization protein 2 (JDP2)	OTW35WKX	JDP2_HUMAN	Increases Expression	[7]
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)	OTBXYFRH	ARAP2_HUMAN	Increases Expression	[7]
Transcription factor AP-2-beta (TFAP2B)	OTR1T8E9	AP2B_HUMAN	Increases Expression	[7]
Protein FAM168A (FAM168A)	OTDXQCS5	F168A_HUMAN	Decreases Expression	[7]
Transcription factor AP-2 gamma (TFAP2C)	OTUDIW05	AP2C_HUMAN	Increases Expression	[7]
Secreted frizzled-related protein 3 (FRZB)	OTTO3DPY	SFRP3_HUMAN	Decreases Expression	[7]
Ras-responsive element-binding protein 1 (RREB1)	OT62460U	RREB1_HUMAN	Increases Expression	[7]
Hyaluronan synthase 2 (HAS2)	OTTD3PAL	HYAS2_HUMAN	Increases Expression	[7]
Coronin-2A (CORO2A)	OTVK7PK3	COR2A_HUMAN	Increases Expression	[7]
Histone acetyltransferase KAT2B (KAT2B)	OTWQITWK	KAT2B_HUMAN	Decreases Expression	[7]
Protein kinase C-binding protein NELL1 (NELL1)	OTF3TX3N	NELL1_HUMAN	Increases Expression	[7]
Kinesin-associated protein 3 (KIFAP3)	OT450PAO	KIFA3_HUMAN	Increases Expression	[7]
BLOC-3 complex member HPS1 (HPS1)	OTKS5I7T	HPS1_HUMAN	Increases Expression	[7]
Deleted in azoospermia-like (DAZL)	OTZMTD4R	DAZL_HUMAN	Decreases Expression	[7]
Receptor-type tyrosine-protein phosphatase N2 (PTPRN2)	OTL6SH28	PTPR2_HUMAN	Decreases Expression	[7]
Stathmin-2 (STMN2)	OT0FUHLH	STMN2_HUMAN	Increases Expression	[7]
Protein naked cuticle homolog 1 (NKD1)	OTY3MO97	NKD1_HUMAN	Increases Expression	[7]
Protein TMEPAI (PMEPA1)	OTY8Z9UF	PMEPA_HUMAN	Increases Expression	[7]
Mitochondrial amidoxime reducing component 2 (MTARC2)	OT8B6LVD	MARC2_HUMAN	Increases Expression	[7]
Terminal nucleotidyltransferase 5B (TENT5B)	OTO2P28B	TET5B_HUMAN	Increases Expression	[7]
Copine-4 (CPNE4)	OTTAGM5L	CPNE4_HUMAN	Increases Expression	[7]
SPRY domain-containing SOCS box protein 4 (SPSB4)	OTG9MLO4	SPSB4_HUMAN	Increases Expression	[7]
SOSS complex subunit B2 (NABP1)	OTFTNFHW	SOSB2_HUMAN	Increases Expression	[7]
Ras-related protein Rab-7b (RAB7B)	OT60A0E9	RAB7B_HUMAN	Increases Expression	[7]
Transmembrane protein 125 (TMEM125)	OTWF8MC1	TM125_HUMAN	Increases Expression	[7]
Claudin-23 (CLDN23)	OTN5RV40	CLD23_HUMAN	Increases Expression	[7]
Transmembrane protein 18 (TMEM18)	OT05YQ1E	TMM18_HUMAN	Decreases Expression	[7]
Repulsive guidance molecule A (RGMA)	OTZAMDO2	RGMA_HUMAN	Decreases Expression	[7]
SH3 domain-containing kinase-binding protein 1 (SH3KBP1)	OTIUA60B	SH3K1_HUMAN	Increases Expression	[7]
Serine/threonine-protein kinase Sgk3 (SGK3)	OTQ6QO99	SGK3_HUMAN	Increases Expression	[7]
BTB/POZ domain-containing protein KCTD12 (KCTD12)	OTPYKT4Z	KCD12_HUMAN	Increases Expression	[7]
Endoplasmic reticulum resident protein 27 (ERP27)	OTVMGE2H	ERP27_HUMAN	Increases Expression	[7]
Polyadenylate-binding protein 5 (PABPC5)	OTLUTQ02	PABP5_HUMAN	Increases Expression	[7]
Ras-related protein Rab-3C (RAB3C)	OTFTJNGA	RAB3C_HUMAN	Increases Expression	[7]
Elongator complex protein 4 (ELP4)	OTP5GZ9V	ELP4_HUMAN	Decreases Expression	[7]
Multivesicular body subunit 12A (MVB12A)	OT3737K0	MB12A_HUMAN	Decreases Expression	[7]
CB1 cannabinoid receptor-interacting protein 1 (CNRIP1)	OTXPWJ56	CNRP1_HUMAN	Increases Expression	[7]
Protein FAM89A (FAM89A)	OTNASAXT	FA89A_HUMAN	Increases Expression	[7]
Secreted frizzled-related protein 2 (SFRP2)	OT8GZ0CA	SFRP2_HUMAN	Decreases Expression	[7]
Transmembrane protein 169 (TMEM169)	OTKXDYVC	TM169_HUMAN	Decreases Expression	[7]
4-hydroxyphenylpyruvate dioxygenase-like protein (HPDL)	OTW7D1SV	HPDL_HUMAN	Increases Expression	[7]
Epithelial-stromal interaction protein 1 (EPSTI1)	OT75I1UH	ESIP1_HUMAN	Increases Expression	[7]
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1)	OTY5HZN5	LRIG1_HUMAN	Decreases Expression	[7]
Microtubule-associated protein 6 (MAP6)	OTPUI00F	MAP6_HUMAN	Decreases Expression	[7]
Coiled-coil domain-containing protein 136 (CCDC136)	OTPOV391	CC136_HUMAN	Decreases Expression	[7]
Golgi-associated RAB2 interactor protein 1B (GARIN1B)	OTWPN527	GAR1B_HUMAN	Decreases Expression	[7]
Phospholipase A and acyltransferase 5 (PLAAT5)	OT9JFFO2	PLAT5_HUMAN	Increases Expression	[7]
Sushi domain-containing protein 3 (SUSD3)	OTERJTUL	SUSD3_HUMAN	Increases Expression	[7]
Guanine nucleotide exchange factor C9orf72 (C9ORF72)	OT0WH38E	CI072_HUMAN	Decreases Expression	[7]
Kremen protein 1 (KREMEN1)	OTGJFSAC	KREM1_HUMAN	Increases Expression	[7]
Transmembrane protein 74 (TMEM74)	OT3IZBM0	TMM74_HUMAN	Decreases Expression	[7]
TOX high mobility group box family member 2 (TOX2)	OT7RZRVK	TOX2_HUMAN	Decreases Expression	[7]
Patched domain-containing protein 1 (PTCHD1)	OTFDLU5S	PTHD1_HUMAN	Increases Expression	[7]
Dachshund homolog 2 (DACH2)	OT33KEUZ	DACH2_HUMAN	Increases Expression	[7]
Chloride intracellular channel protein 6 (CLIC6)	OTFMSU5U	CLIC6_HUMAN	Increases Expression	[7]
Noelin-3 (OLFM3)	OTBHPDTL	NOE3_HUMAN	Increases Expression	[7]
Leucine-rich repeat-containing protein 3B (LRRC3B)	OT9VDGPR	LRC3B_HUMAN	Decreases Expression	[7]
Secretoglobin family 3A member 2 (SCGB3A2)	OTB63PHR	SG3A2_HUMAN	Increases Expression	[7]
VPS10 domain-containing receptor SorCS2 (SORCS2)	OTBF3DYK	SORC2_HUMAN	Decreases Expression	[7]
Rho GTPase-activating protein 7 (DLC1)	OTP8LMCR	RHG07_HUMAN	Increases Expression	[7]
DEP domain-containing protein 7 (DEPDC7)	OT62C942	DEPD7_HUMAN	Increases Expression	[7]
Rab-3A-interacting protein (RAB3IP)	OT3UPQAA	RAB3I_HUMAN	Decreases Expression	[7]
Homeobox protein ARX (ARX)	OTBGYH25	ARX_HUMAN	Decreases Expression	[7]
Lipase maturation factor 1 (LMF1)	OTOL14ZD	LMF1_HUMAN	Increases Expression	[7]
Doublesex- and mab-3-related transcription factor A2 (DMRTA2)	OTWQR1M7	DMTA2_HUMAN	Increases Expression	[7]
Mucin-4 (MUC4)	OTLT11V1	MUC4_HUMAN	Increases Expression	[7]
Glutamate decarboxylase 1 (GAD1)	OT52Z39J	DCE1_HUMAN	Increases Expression	[7]
Protein kinase C-binding protein NELL2 (NELL2)	OTS4MJZ7	NELL2_HUMAN	Decreases Expression	[7]
Sphingosine 1-phosphate receptor 3 (S1PR3)	OTXBIYO8	S1PR3_HUMAN	Decreases Expression	[7]
Krueppel-like factor 6 (KLF6)	OTQY9S7F	KLF6_HUMAN	Increases Expression	[7]
Fasciculation and elongation protein zeta-1 (FEZ1)	OTWCXPRE	FEZ1_HUMAN	Decreases Expression	[7]
Pituitary homeobox 2 (PITX2)	OTWMXAOY	PITX2_HUMAN	Increases Expression	[7]
Endothelial PAS domain-containing protein 1 (EPAS1)	OTRE3O8U	EPAS1_HUMAN	Increases Expression	[7]
Epidermal growth factor-like protein 8 (EGFL8)	OTECTJ7K	EGFL8_HUMAN	Increases Expression	[7]
Forkhead box protein C2 (FOXC2)	OT83P1E0	FOXC2_HUMAN	Increases Expression	[7]
Cbp/p300-interacting transactivator 2 (CITED2)	OT812TV7	CITE2_HUMAN	Increases Expression	[7]
Retinoic acid receptor responder protein 2 (RARRES2)	OT1BJE8K	RARR2_HUMAN	Increases Expression	[7]
Semaphorin-3C (SEMA3C)	OTEGUY7F	SEM3C_HUMAN	Increases Expression	[7]
Fermitin family homolog 1 (FERMT1)	OT626PBA	FERM1_HUMAN	Increases Expression	[7]
Synaptotagmin-11 (SYT11)	OTLRTZEI	SYT11_HUMAN	Decreases Expression	[7]
Brain-enriched guanylate kinase-associated protein (BEGAIN)	OTT3UD2K	BEGIN_HUMAN	Decreases Expression	[7]
Protein ABHD14A (ABHD14A)	OT94GKE1	ABHEA_HUMAN	Decreases Expression	[7]
Ribonuclease P protein subunit p25 (RPP25)	OTEN6QN7	RPP25_HUMAN	Increases Expression	[7]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1)	OTJGE772	CHAC1_HUMAN	Increases Expression	[7]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ST6GALNAC5)	OTH91ETM	SIA7E_HUMAN	Decreases Expression	[7]
Cell cycle regulator of non-homologous end joining (CYREN)	OT5ZL00R	CYREN_HUMAN	Decreases Expression	[7]
Brother of CDO (BOC)	OTXBCY9W	BOC_HUMAN	Increases Expression	[7]
RNA-binding protein 24 (RBM24)	OTQI1AR1	RBM24_HUMAN	Decreases Expression	[7]
Receptor for retinol uptake STRA6 (STRA6)	OT2IDF27	STRA6_HUMAN	Increases Expression	[7]
Sphingosine-1-phosphate phosphatase 1 (SGPP1)	OT9X54CQ	SGPP1_HUMAN	Increases Expression	[7]
Sal-like protein 3 (SALL3)	OTJ2LZKQ	SALL3_HUMAN	Decreases Expression	[7]
Oxysterol-binding protein-related protein 10 (OSBPL10)	OT0TFMBE	OSB10_HUMAN	Increases Expression	[7]
Complement C1q tumor necrosis factor-related protein 4 (C1QTNF4)	OTHD4Y9D	C1QT4_HUMAN	Decreases Expression	[7]
Microtubule-associated proteins 1A/1B light chain 3C (MAP1LC3C)	OTM4ECDK	MLP3C_HUMAN	Increases Expression	[7]
R-spondin-3 (RSPO3)	OTZK8GDS	RSPO3_HUMAN	Increases Expression	[7]
Histone deacetylase 8 (HDAC8)	OT5L4RYX	HDAC8_HUMAN	Increases Expression	[7]
Dedicator of cytokinesis protein 9 (DOCK9)	OT84H8AD	DOCK9_HUMAN	Increases Expression	[7]
Iroquois-class homeodomain protein IRX-2 (IRX2)	OTBHXXQ2	IRX2_HUMAN	Increases Expression	[7]
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 (NMNAT2)	OT5JLP2H	NMNA2_HUMAN	Increases Expression	[7]
Thiamine transporter 2 (SLC19A3)	OTOWP1CT	S19A3_HUMAN	Increases Expression	[7]
E3 ubiquitin-protein ligase TRIM9 (TRIM9)	OTKYG33W	TRIM9_HUMAN	Increases Expression	[7]
Tripartite motif-containing protein 6 (TRIM6)	OTBSMX0B	TRIM6_HUMAN	Increases Expression	[7]
Protein TANC1 (TANC1)	OTF6TZ8E	TANC1_HUMAN	Increases Expression	[7]
Ethanolaminephosphotransferase 1 (SELENOI)	OTX2A47A	EPT1_HUMAN	Increases Expression	[7]
SRC kinase signaling inhibitor 1 (SRCIN1)	OTQZNQQ5	SRCN1_HUMAN	Decreases Expression	[7]
Metal cation symporter ZIP8 (SLC39A8)	OT6C6MNV	S39A8_HUMAN	Increases Expression	[7]
Immortalization up-regulated protein (C19ORF33)	OTOYH74A	IMUP_HUMAN	Increases Expression	[7]
PR domain zinc finger protein 14 (PRDM14)	OTWZKY4L	PRD14_HUMAN	Increases Expression	[7]
NUAK family SNF1-like kinase 2 (NUAK2)	OTUEZLO8	NUAK2_HUMAN	Decreases Expression	[7]
CYFIP-related Rac1 interactor A (CYRIA)	OT2VJ767	CYRIA_HUMAN	Increases Expression	[7]
Ras-related protein Rab-17 (RAB17)	OT7NBUGQ	RAB17_HUMAN	Increases Expression	[7]
B-cell lymphoma/leukemia 11A (BCL11A)	OTI6ZBP6	BC11A_HUMAN	Increases Expression	[7]
Kinesin-like protein KIF13A (KIF13A)	OTSSZGBQ	KI13A_HUMAN	Decreases Expression	[7]
Sphingosine 1-phosphate receptor 5 (S1PR5)	OTQF1R0U	S1PR5_HUMAN	Increases Expression	[7]
Synaptotagmin-4 (SYT4)	OTA1D7VL	SYT4_HUMAN	Increases Expression	[7]
Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1)	OT38HXJP	CRLD1_HUMAN	Increases Expression	[7]
Sorting nexin-25 (SNX25)	OT8JY8M1	SNX25_HUMAN	Decreases Expression	[7]
Leucine-rich repeat neuronal protein 3 (LRRN3)	OT7X0AA7	LRRN3_HUMAN	Increases Expression	[7]
Calsyntenin-2 (CLSTN2)	OT2PJYHX	CSTN2_HUMAN	Increases Expression	[7]
SPARC-related modular calcium-binding protein 1 (SMOC1)	OTJG2JQY	SMOC1_HUMAN	Decreases Expression	[7]
DNA transposase THAP9 (THAP9)	OTY4TSJO	THAP9_HUMAN	Decreases Expression	[7]
SLIT and NTRK-like protein 6 (SLITRK6)	OTLNWI5G	SLIK6_HUMAN	Increases Expression	[7]
Epithelial splicing regulatory protein 2 (ESRP2)	OTVTKJ4I	ESRP2_HUMAN	Increases Expression	[7]
Dedicator of cytokinesis protein 5 (DOCK5)	OT63I0CL	DOCK5_HUMAN	Increases Expression	[7]
NIPA-like protein 2 (NIPAL2)	OTX9UREP	NPAL2_HUMAN	Increases Expression	[7]
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial (MTHFD2L)	OTDYNXRG	MTD2L_HUMAN	Increases Expression	[7]
Nuclear body protein SP140-like protein (SP140L)	OTL30JKT	SP14L_HUMAN	Increases Expression	[7]
Chondrolectin (CHODL)	OTVCNOUQ	CHODL_HUMAN	Increases Expression	[7]
Homeobox protein NANOG (NANOG)	OTUEY1FM	NANOG_HUMAN	Increases Expression	[7]
Adhesion G protein-coupled receptor L3 (ADGRL3)	OT81Q8LY	AGRL3_HUMAN	Decreases Expression	[7]
Netrin-4 (NTN4)	OTDRRMP3	NET4_HUMAN	Decreases Expression	[7]
V-type proton ATPase 116 kDa subunit a 4 (ATP6V0A4)	OT149Z7Q	VPP4_HUMAN	Increases Expression	[7]
Collectrin (CLTRN)	OTXGFJ3F	CLTRN_HUMAN	Decreases Expression	[7]
Ethanolamine kinase 1 (ETNK1)	OTDKB4DQ	EKI1_HUMAN	Increases Expression	[7]
Popeye domain-containing protein 3 (POPDC3)	OTN4FJ5J	POPD3_HUMAN	Decreases Expression	[7]
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2)	OTAQD3YV	ARNT2_HUMAN	Decreases Expression	[7]
Prokineticin-2 (PROK2)	OT70IFEZ	PROK2_HUMAN	Decreases Expression	[7]
Sodium/potassium/calcium exchanger 3 (SLC24A3)	OTEJN38N	NCKX3_HUMAN	Increases Expression	[7]
Mineralization regulator ANKH (ANKH)	OTCN25R5	ANKH_HUMAN	Increases Expression	[7]
UPF0606 protein KIAA1549 (KIAA1549)	OTA5B18F	K1549_HUMAN	Decreases Expression	[7]
Band 4.1-like protein 5 (EPB41L5)	OTPPQPLU	E41L5_HUMAN	Increases Expression	[7]
Solute carrier family 40 member 1 (SLC40A1)	OT8RV2VY	S40A1_HUMAN	Increases Expression	[7]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A)	OT5V52LN	TNR12_HUMAN	Increases Expression	[7]
Mid1-interacting protein 1 (MID1IP1)	OTFCORJM	M1IP1_HUMAN	Increases Expression	[7]
Frizzled-3 (FZD3)	OTIWDN78	FZD3_HUMAN	Decreases Expression	[7]
Nuclear receptor-interacting protein 3 (NRIP3)	OTU15GMK	NRIP3_HUMAN	Decreases Expression	[7]
Signal peptide, CUB and EGF-like domain-containing protein 2 (SCUBE2)	OT661S7D	SCUB2_HUMAN	Decreases Expression	[7]
Solute carrier family 52, riboflavin transporter, member 3 (SLC52A3)	OT1FHFMK	S52A3_HUMAN	Increases Expression	[7]
E3 ubiquitin-protein ligase Jade-2 (JADE2)	OTVG2MYF	JADE2_HUMAN	Increases Expression	[7]
Ras-related GTP-binding protein D (RRAGD)	OTXLVWAH	RRAGD_HUMAN	Decreases Expression	[7]
Coiled-coil domain-containing protein 177 (CCDC177)	OT44WWP5	CC177_HUMAN	Decreases Expression	[7]
Sialic acid synthase (NANS)	OTMQ2FUH	SIAS_HUMAN	Increases Expression	[7]
Platelet-derived growth factor C (PDGFC)	OT3ZJ0XU	PDGFC_HUMAN	Increases Expression	[7]
N-lysine methyltransferase SMYD2 (SMYD2)	OTN8035R	SMYD2_HUMAN	Increases Expression	[7]
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)	OTWHOVZS	BAZ1A_HUMAN	Increases Expression	[7]
Olfactomedin-like protein 3 (OLFML3)	OTDN45FN	OLFL3_HUMAN	Increases Expression	[7]
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (C1GALT1)	OT2ZSZ6P	C1GLT_HUMAN	Increases Expression	[7]
Glutaredoxin-2, mitochondrial (GLRX2)	OT4LIRBC	GLRX2_HUMAN	Increases Expression	[7]
Protein reprimo (RPRM)	OTNNBAS1	RPRM_HUMAN	Increases Expression	[7]
Probable G-protein coupled receptor 173 (GPR173)	OT8F8XR1	GP173_HUMAN	Decreases Expression	[7]
Probable G-protein coupled receptor 27 (GPR27)	OTH4KQPI	GPR27_HUMAN	Decreases Expression	[7]
Asc-type amino acid transporter 1 (SLC7A10)	OTN1S03Q	AAA1_HUMAN	Increases Expression	[7]
EMILIN-3 (EMILIN3)	OT2BZTSU	EMIL3_HUMAN	Decreases Expression	[7]
Teneurin-2 (TENM2)	OTPLUYEF	TEN2_HUMAN	Increases Expression	[7]
Obg-like ATPase 1 (OLA1)	OTAPOTTG	OLA1_HUMAN	Decreases Expression	[7]
Muscleblind-like protein 3 (MBNL3)	OT2T2YOK	MBNL3_HUMAN	Increases Expression	[7]
RNA binding protein fox-1 homolog 1 (RBFOX1)	OTFPKEL7	RFOX1_HUMAN	Increases Expression	[7]
Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUB)	OTXLLSIZ	MCUB_HUMAN	Decreases Expression	[7]
Ras-related protein Rab-20 (RAB20)	OTP9OOVS	RAB20_HUMAN	Increases Expression	[7]
Very long chain fatty acid elongase 2 (ELOVL2)	OTDAF6U3	ELOV2_HUMAN	Decreases Expression	[7]
Sphingosine kinase 1 (SPHK1)	OTWYPBVD	SPHK1_HUMAN	Increases Expression	[7]
Dapper homolog 1 (DACT1)	OT19Z704	DACT1_HUMAN	Increases Expression	[7]
Endoplasmic reticulum aminopeptidase 1 (ERAP1)	OT72S99B	ERAP1_HUMAN	Decreases Expression	[7]
Transcription factor CP2-like protein 1 (TFCP2L1)	OT7QIJ0X	TF2L1_HUMAN	Increases Expression	[7]
Myoferlin (MYOF)	OTRFC3IJ	MYOF_HUMAN	Increases Expression	[7]
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1)	OTW3T4B2	IRPL1_HUMAN	Decreases Expression	[7]
Tropomodulin-2 (TMOD2)	OTTTUH2W	TMOD2_HUMAN	Increases Expression	[7]
Potassium voltage-gated channel subfamily D member 2 (KCND2)	OTIFUVV7	KCND2_HUMAN	Decreases Expression	[7]
Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22)	OT452ZDC	ADA22_HUMAN	Decreases Expression	[7]
DOMON domain-containing protein FRRS1L (FRRS1L)	OT24ABVC	FRS1L_HUMAN	Decreases Expression	[7]
Peroxisomal sarcosine oxidase (PIPOX)	OTWTCOTN	SOX_HUMAN	Increases Expression	[7]
MyoD family inhibitor domain-containing protein (MDFIC)	OTSRYBWZ	MDFIC_HUMAN	Increases Expression	[7]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1)	OTJISZOX	PLCE1_HUMAN	Increases Expression	[7]
Junctional cadherin 5-associated protein (JCAD)	OT7G1WJW	JCAD_HUMAN	Increases Expression	[7]
Protocadherin-10 (PCDH10)	OT2GIT0E	PCD10_HUMAN	Increases Expression	[7]
Kelch-like protein 14 (KLHL14)	OTYOS55H	KLH14_HUMAN	Increases Expression	[7]
Short transient receptor potential channel 4 (TRPC4)	OTYY9DPV	TRPC4_HUMAN	Decreases Expression	[7]
Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2)	OTU4J3ZI	HEY2_HUMAN	Increases Expression	[7]
Homeobox expressed in ES cells 1 (HESX1)	OT5E2Z4G	HESX1_HUMAN	Decreases Expression	[7]
Small conductance calcium-activated potassium channel protein 3 (KCNN3)	OT11KYA8	KCNN3_HUMAN	Decreases Expression	[7]
Testin (TES)	OTL8PP6V	TES_HUMAN	Increases Expression	[7]
Sushi domain-containing protein 2 (SUSD2)	OTSJTAZP	SUSD2_HUMAN	Increases Expression	[7]
Transcription factor COE1 (EBF1)	OTZ61YYH	COE1_HUMAN	Increases Expression	[7]
Zinc finger transcription factor Trps1 (TRPS1)	OT7XPPEL	TRPS1_HUMAN	Increases Expression	[7]
Scm-like with four MBT domains protein 1 (SFMBT1)	OTKMZIBW	SMBT1_HUMAN	Decreases Expression	[7]
Krueppel-like factor 15 (KLF15)	OTGMQMVR	KLF15_HUMAN	Increases Expression	[7]
E3 ISG15--protein ligase HERC5 (HERC5)	OTZ5PR39	HERC5_HUMAN	Increases Expression	[7]
Potassium voltage-gated channel subfamily G member 1 (KCNG1)	OTZ9ZRG8	KCNG1_HUMAN	Increases Expression	[7]
Forkhead box protein D3 (FOXD3)	OTXYV6GO	FOXD3_HUMAN	Increases Expression	[7]
Purine-rich element-binding protein gamma (PURG)	OTXPQDWN	PURG_HUMAN	Decreases Expression	[7]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (GNG8)	OT9YHSF1	GBG8_HUMAN	Decreases Expression	[7]
F-box only protein 2 (FBXO2)	OTF3677S	FBX2_HUMAN	Increases Expression	[7]
Ribosomal protein S6 kinase alpha-6 (RPS6KA6)	OTTY0FI2	KS6A6_HUMAN	Decreases Expression	[7]
Nocturnin (NOCT)	OTVSYP2D	NOCT_HUMAN	Increases Expression	[7]
Adherens junction-associated protein 1 (AJAP1)	OTAAW121	AJAP1_HUMAN	Increases Expression	[7]
TRAF2 and NCK-interacting protein kinase (TNIK)	OTDZBJ4K	TNIK_HUMAN	Increases Expression	[7]
Cdc42 effector protein 3 (CDC42EP3)	OTUZ3U9Z	BORG2_HUMAN	Decreases Expression	[7]
Disintegrin and metalloproteinase domain-containing protein 28 (ADAM28)	OT3GBVHL	ADA28_HUMAN	Increases Expression	[7]
ETS-related transcription factor Elf-5 (ELF5)	OTLRU8YF	ELF5_HUMAN	Increases Expression	[7]
Procollagen C-endopeptidase enhancer 2 (PCOLCE2)	OTSUEQZ1	PCOC2_HUMAN	Increases Expression	[7]
DENN domain-containing protein 2A (DENND2A)	OT01E1PL	DEN2A_HUMAN	Decreases Expression	[7]
NACHT and WD repeat domain-containing protein 2 (NWD2)	OTN47UBK	NWD2_HUMAN	Increases Expression	[7]
Protein HEG homolog 1 (HEG1)	OT3CUXA7	HEG1_HUMAN	Decreases Expression	[7]
Neurabin-1 (PPP1R9A)	OTJL2TOC	NEB1_HUMAN	Decreases Expression	[7]
RING finger protein 150 (RNF150)	OTAMSBK5	RN150_HUMAN	Increases Expression	[7]
E3 ubiquitin-protein ligase CBL-C (CBLC)	OT3RKZI9	CBLC_HUMAN	Increases Expression	[7]
Frizzled-10 (FZD10)	OTSAENLT	FZD10_HUMAN	Increases Expression	[7]
Apoptosis-associated speck-like protein containing a CARD (PYCARD)	OT67RON3	ASC_HUMAN	Increases Expression	[7]
Sex comb on midleg-like protein 1 (SCML1)	OT7V5DAR	SCML1_HUMAN	Increases Expression	[7]
DNA polymerase iota (POLI)	OTBA4DCE	POLI_HUMAN	Decreases Expression	[7]
LIM and calponin homology domains-containing protein 1 (LIMCH1)	OTYPC4XA	LIMC1_HUMAN	Decreases Expression	[7]
Cystine/glutamate transporter (SLC7A11)	OTKJ6PXW	XCT_HUMAN	Increases Expression	[7]
Catenin delta-2 (CTNND2)	OTYKE30Y	CTND2_HUMAN	Decreases Expression	[7]
Tenascin-N (TNN)	OTQK2AMX	TENN_HUMAN	Increases Expression	[7]
Short transient receptor potential channel 6 (TRPC6)	OT5J7HVM	TRPC6_HUMAN	Increases Expression	[7]
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 (FUT9)	OTLIJBQY	FUT9_HUMAN	Decreases Expression	[7]
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A)	OT74EK7Z	PDE10_HUMAN	Decreases Expression	[7]
Leucine zipper putative tumor suppressor 1 (LZTS1)	OTXXL864	LZTS1_HUMAN	Increases Expression	[7]
C-C motif chemokine 26 (CCL26)	OT2B7HR9	CCL26_HUMAN	Increases Expression	[7]
TBC1 domain family member 30 (TBC1D30)	OTG8HGSI	TBC30_HUMAN	Decreases Expression	[7]
Band 4.1-like protein 3 (EPB41L3)	OTS6CHG2	E41L3_HUMAN	Increases Expression	[7]
Axin-2 (AXIN2)	OTRMGQNU	AXIN2_HUMAN	Increases Expression	[7]
Retinal homeobox protein Rx (RAX)	OTJ3YCE7	RX_HUMAN	Decreases Expression	[7]
Tudor and KH domain-containing protein (TDRKH)	OTV21BN1	TDRKH_HUMAN	Decreases Expression	[7]
Transmembrane emp24 domain-containing protein 5 (TMED5)	OT70W1J8	TMED5_HUMAN	Increases Expression	[7]
C2 domain-containing protein 2 (C2CD2)	OTL1K0OB	C2CD2_HUMAN	Decreases Expression	[7]
Sal-like protein 2 (SALL2)	OTQWI68Q	SALL2_HUMAN	Decreases Expression	[7]
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2)	OTJBDX0Y	VPP2_HUMAN	Decreases Expression	[7]
Beta/gamma crystallin domain-containing protein 1 (CRYBG1)	OTIPDI15	CRBG1_HUMAN	Increases Expression	[7]
Transcription factor HES-2 (HES2)	OTMWY2KV	HES2_HUMAN	Increases Expression	[7]
Intraflagellar transport protein 25 homolog (IFT25)	OTDR1HG6	IFT25_HUMAN	Decreases Expression	[7]
Low-density lipoprotein receptor-related protein 12 (LRP12)	OTRT1UJ7	LRP12_HUMAN	Decreases Expression	[7]
Protein mab-21-like 2 (MAB21L2)	OTZM5VMX	MB212_HUMAN	Decreases Expression	[7]
Protocadherin beta-14 (PCDHB14)	OTFZF1ST	PCDBE_HUMAN	Decreases Expression	[7]
Transcription factor MafB (MAFB)	OTH2N3T8	MAFB_HUMAN	Increases Expression	[7]
Neuropeptide FF receptor 2 (NPFFR2)	OTVI4Q85	NPFF2_HUMAN	Increases Expression	[7]
Beta-secretase 2 (BACE2)	OTO5YQVK	BACE2_HUMAN	Increases Expression	[7]
Glypican-6 (GPC6)	OTNJBESF	GPC6_HUMAN	Decreases Expression	[7]
Adhesion G-protein coupled receptor G1 (ADGRG1)	OTQBB8NT	AGRG1_HUMAN	Decreases Expression	[7]
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1)	OTK53GUD	HS3SB_HUMAN	Decreases Expression	[7]
LHFPL tetraspan subfamily member 6 protein (LHFPL6)	OTY6LHJY	LHPL6_HUMAN	Increases Expression	[7]
Mitochondrial inner membrane protease ATP23 homolog (ATP23)	OT303R2T	ATP23_HUMAN	Increases Expression	[7]
Gap junction alpha-3 protein (GJA3)	OTXV6ETF	CXA3_HUMAN	Increases Expression	[7]
Sulfide:quinone oxidoreductase, mitochondrial (SQOR)	OTTLD0KB	SQOR_HUMAN	Increases Expression	[7]
Cadherin-10 (CDH10)	OTK3D5WP	CAD10_HUMAN	Increases Expression	[7]
Calpain-6 (CAPN6)	OT8K5PR5	CAN6_HUMAN	Decreases Expression	[7]
AP-1 complex subunit mu-2 (AP1M2)	OTUE5YLC	AP1M2_HUMAN	Increases Expression	[7]
Dual specificity protein phosphatase 10 (DUSP10)	OTNG467B	DUS10_HUMAN	Increases Expression	[7]
Collagen alpha-1(XI) chain (COL11A1)	OTB0DRMS	COBA1_HUMAN	Increases Expression	[14]
Neuronal growth regulator 1 (NEGR1)	OT57ECW9	NEGR1_HUMAN	Increases Expression	[14]
Bone morphogenetic protein receptor type-1B (BMPR1B)	OTGFN0OD	BMR1B_HUMAN	Affects Expression	[9]
Huntingtin-interacting protein 1 (HIP1)	OT7AKCFQ	HIP1_HUMAN	Increases Expression	[8]
Homeobox protein Meis2 (MEIS2)	OTG4ADLM	MEIS2_HUMAN	Affects Expression	[9]
T-box transcription factor TBX3 (TBX3)	OTM64N7K	TBX3_HUMAN	Affects Expression	[9]
Baculoviral IAP repeat-containing protein 5 (BIRC5)	OTILXZYL	BIRC5_HUMAN	Decreases Expression	[15]
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 (ST8SIA3)	OTG9MXV9	SIA8C_HUMAN	Affects Expression	[9]
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3)	OTX1C2GS	DYRK3_HUMAN	Increases Expression	[8]
Transmembrane and coiled-coil domains protein 2 (TMCC2)	OT0D7IYD	TMCC2_HUMAN	Increases Expression	[8]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G)	OT8V1J4M	GA45G_HUMAN	Increases Expression	[16]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Increases Acetylation	[16]
Nuclear factor 1 C-type (NFIC)	OTLMCUIB	NFIC_HUMAN	Affects Expression	[9]
Myb-related protein A (MYBL1)	OTBJMC2P	MYBA_HUMAN	Increases Expression	[8]
Histone H2AX (H2AX)	OT18UX57	H2AX_HUMAN	Increases Expression	[17]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Increases Expression	[16]
Interleukin-3 receptor subunit alpha (IL3RA)	OTDC3Y8O	IL3RA_HUMAN	Increases Expression	[8]
G-protein coupled receptor 183 (GPR183)	OTRILX7G	GP183_HUMAN	Decreases Expression	[8]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[18]
Signal transducer and activator of transcription 3 (STAT3)	OTAAGKYZ	STAT3_HUMAN	Increases Acetylation	[19]
OX-2 membrane glycoprotein (CD200)	OTQEQSRT	OX2G_HUMAN	Affects Expression	[9]
Tyrosine-protein phosphatase non-receptor type 9 (PTPN9)	OTNAR1I2	PTN9_HUMAN	Affects Expression	[9]
Cyclin-dependent kinase inhibitor 1B (CDKN1B)	OTNY5LLZ	CDN1B_HUMAN	Increases Expression	[18]
Actin, aortic smooth muscle (ACTA2)	OTEDLG8E	ACTA_HUMAN	Decreases Expression	[15]
Histone H4 (H4C1)	OTB71W46	H4_HUMAN	Increases Acetylation	[20]
Guanylate cyclase soluble subunit alpha-1 (GUCY1A1)	OTPTCBUN	GCYA1_HUMAN	Affects Expression	[9]
Unconventional myosin-Ie (MYO1E)	OTM9YSIZ	MYO1E_HUMAN	Increases Expression	[8]
Cyclin-dependent kinase 5 activator 1 (CDK5R1)	OTJELWK0	CD5R1_HUMAN	Decreases Expression	[8]
Histone H3.1t (H3-4)	OTY6ITYF	H31T_HUMAN	Increases Acetylation	[20]
Rho GTPase-activating protein 31 (ARHGAP31)	OTUYTF4I	RHG31_HUMAN	Affects Expression	[9]
Fidgetin (FIGN)	OTJF6EZR	FIGN_HUMAN	Affects Expression	[9]
NHS-like protein 2 (NHSL2)	OT8U1P8E	NHSL2_HUMAN	Affects Expression	[9]
Failed axon connections homolog (FAXC)	OTU0RGB0	FAXC_HUMAN	Affects Expression	[9]
AT-rich interactive domain-containing protein 2 (ARID2)	OTIRJXWM	ARID2_HUMAN	Affects Expression	[9]
Male-specific lethal 1 homolog (MSL1)	OTXLFYLB	MSL1_HUMAN	Decreases Expression	[8]
Rab11 family-interacting protein 1 (RAB11FIP1)	OT0T71OW	RFIP1_HUMAN	Increases Expression	[8]
Protein lin-28 homolog B (LIN28B)	OTVWP0FN	LN28B_HUMAN	Decreases Expression	[9]
Leucine-rich repeat transmembrane neuronal protein 1 (LRRTM1)	OTKI3IU9	LRRT1_HUMAN	Affects Expression	[9]
Transforming growth factor beta activator LRRC33 (NRROS)	OT9WNOKY	LRC33_HUMAN	Decreases Expression	[8]
tRNA-uridine aminocarboxypropyltransferase 1 (DTWD1)	OT95QT6P	DTWD1_HUMAN	Decreases Expression	[8]
TBC1 domain family member 16 (TBC1D16)	OTPR3C6A	TBC16_HUMAN	Increases Expression	[8]
Transforming growth factor-beta receptor-associated protein 1 (TGFBRAP1)	OT80QNR5	TGFA1_HUMAN	Affects Expression	[9]
Alpha-2,8-sialyltransferase 8B (ST8SIA2)	OTRBBBD8	SIA8B_HUMAN	Affects Expression	[9]
Protein FAN (NSMAF)	OTYNVZ23	FAN_HUMAN	Affects Expression	[9]
Protein Jumonji (JARID2)	OT14UM8H	JARD2_HUMAN	Increases Expression	[8]
ELL-associated factor 2 (EAF2)	OTSOET5L	EAF2_HUMAN	Increases Expression	[8]
Abasic site processing protein HMCES (HMCES)	OTVRDL6U	HMCES_HUMAN	Increases Expression	[8]
Protein FAM163A (FAM163A)	OT0MYZ0F	F163A_HUMAN	Affects Expression	[9]
Bcl-2-modifying factor (BMF)	OT90NSLI	BMF_HUMAN	Increases Expression	[8]
Small integral membrane protein 14 (SMIM14)	OT47IF19	SIM14_HUMAN	Increases Expression	[8]
Sialidase-1 (NEU1)	OTH9BY8Y	NEUR1_HUMAN	Increases Expression	[8]
Partner of Y14 and mago (PYM1)	OTEZ2WUO	PYM1_HUMAN	Decreases Expression	[8]
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1)	OTM3B3OA	TBL1R_HUMAN	Affects Expression	[9]
E3 ubiquitin-protein ligase TRIM8 (TRIM8)	OTS6JFR0	TRIM8_HUMAN	Affects Expression	[9]
Sentrin-specific protease 6 (SENP6)	OT05LLF4	SENP6_HUMAN	Affects Expression	[9]
Tumor protein 63 (TP63)	OT0WOOKQ	P63_HUMAN	Increases Expression	[21]
Popeye domain-containing protein 2 (POPDC2)	OTDAZSY5	POPD2_HUMAN	Affects Expression	[9]
F-box only protein 8 (FBXO8)	OTZNGJGW	FBX8_HUMAN	Affects Expression	[9]
Tumor necrosis factor receptor superfamily member 19 (TNFRSF19)	OTTVT4MB	TNR19_HUMAN	Increases Expression	[8]
AP-5 complex subunit sigma-1 (AP5S1)	OTGS53SC	AP5S1_HUMAN	Decreases Expression	[8]
Pre-mRNA-splicing factor RBM22 (RBM22)	OTFW0IGK	RBM22_HUMAN	Decreases Expression	[8]
Ral guanine nucleotide dissociation stimulator-like 1 (RGL1)	OTY6ZHVA	RGL1_HUMAN	Increases Expression	[8]
Programmed cell death 1 ligand 1 (CD274)	OTJ0VFDL	PD1L1_HUMAN	Increases Expression	[19]
Coiled-coil and C2 domain-containing protein 2A (CC2D2A)	OTFGRGFR	C2D2A_HUMAN	Affects Expression	[9]
Histone deacetylase 9 (HDAC9)	OTO8O0LF	HDAC9_HUMAN	Decreases Expression	[15]
Lactosylceramide alpha-2,3-sialyltransferase (ST3GAL5)	OT27CCUF	SIAT9_HUMAN	Increases Expression	[8]
RING finger protein 24 (RNF24)	OTUZI597	RNF24_HUMAN	Increases Expression	[8]
Phosphatidylinositide phosphatase SAC2 (INPP5F)	OTPKUY50	SAC2_HUMAN	Increases Expression	[8]
DmX-like protein 1 (DMXL1)	OTWVL31L	DMXL1_HUMAN	Increases Expression	[8]
Cystathionine beta-synthase (CBS)	OT46FSKD	CBS_HUMAN	Increases ADR	[22]
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15)	OT53SIZG	NAA15_HUMAN	Increases ADR	[22]
Methylenetetrahydrofolate reductase (MTHFR)	OTUBJSR7	MTHR_HUMAN	Increases ADR	[22]

Test Results of This Drug Combination in Other Disease Systems

Indication	DrugCom ID	Cell Line	Status	REF
Diffuse intrinsic pontine glioma	DCWIGQ5	DIPG25	Investigative	[23]

References

• [1] Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.
• [2] ClinicalTrials.gov (NCT03522298) Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma. U.S. National Institutes of Health.
• [3] Panobinostat FDA Label
• [4] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
• [5] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7489).
• [6] Current clinical development of PI3K pathway inhibitors in glioblastoma. Neuro Oncol. 2012 July; 14(7): 819-829.
• [7] A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.
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• [9] The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects. Clin Cancer Res. 2016 May 15;22(10):2534-44. doi: 10.1158/1078-0432.CCR-15-1666. Epub 2016 Jan 5.
• [10] Protein methyltransferases as a target class for drug discovery. Nat Rev Drug Discov. 2009 Sep;8(9):724-32.
• [11] Panobinostat for the treatment of multiple myeloma: the evidence to date. J Blood Med. 2015 Oct 8;6:269-76.
• [12] Panobinostat for the treatment of relapsed or relapsed/refractory multiple myeloma: pharmacology and clinical outcomes. Expert Rev Clin Pharmacol. 2016;9(1):35-48.
• [13] Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells. Mol Cancer Ther. 2014 May;13(5):1142-54.
• [14] Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests. Arch Toxicol. 2017 Feb;91(2):839-864.
• [15] Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis. PLoS One. 2018 Nov 27;13(11):e0207915. doi: 10.1371/journal.pone.0207915. eCollection 2018.
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