DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
G1/S-specific cyclin-D1 (CCND1)
|
OT8HPTKJ
|
CCND1_HUMAN
|
Decreases Expression
|
[4] |
RAC-alpha serine/threonine-protein kinase (AKT1)
|
OT8H2YY7
|
AKT1_HUMAN
|
Decreases Phosphorylation
|
[6] |
Signal transducer and activator of transcription 3 (STAT3)
|
OTAAGKYZ
|
STAT3_HUMAN
|
Decreases Phosphorylation
|
[4] |
Cyclin-dependent kinase inhibitor 1B (CDKN1B)
|
OTNY5LLZ
|
CDN1B_HUMAN
|
Increases Expression
|
[4] |
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)
|
OTOWDUNT
|
PTEN_HUMAN
|
Increases Expression
|
[4] |
Small ribosomal subunit protein eS6 (RPS6)
|
OTT4D1LN
|
RS6_HUMAN
|
Decreases Phosphorylation
|
[6] |
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1)
|
OTHBQVD5
|
4EBP1_HUMAN
|
Decreases Phosphorylation
|
[6] |
Hypoxia-inducible factor 1-alpha (HIF1A)
|
OTADSC03
|
HIF1A_HUMAN
|
Decreases Expression
|
[4] |
Proline-rich AKT1 substrate 1 (AKT1S1)
|
OT4JHN4Y
|
AKTS1_HUMAN
|
Decreases Phosphorylation
|
[6] |
GTPase KRas (KRAS)
|
OT78QCN8
|
RASK_HUMAN
|
Affects Response To Substance
|
[6] |
Serine/threonine-protein kinase B-raf (BRAF)
|
OT7S81XQ
|
BRAF_HUMAN
|
Affects Response To Substance
|
[6] |
Mitogen-activated protein kinase 3 (MAPK3)
|
OTCYKGKO
|
MK03_HUMAN
|
Affects Response To Substance
|
[6] |
Mitogen-activated protein kinase 1 (MAPK1)
|
OTH85PI5
|
MK01_HUMAN
|
Affects Response To Substance
|
[6] |
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