Details of the Drug Combinations

General Information of This Drug (ID: DM0CEY3)

Drug Name
Lefaxin   DM0CEY3
Synonyms
PYRIDOSTIGMINE BROMIDE; 101-26-8; Mestinon; Kalimin; Regonal; Kalymin; Mestinon bromide; 3-((Dimethylcarbamoyl)oxy)-1-methylpyridin-1-ium bromide; 3-(Dimethylcarbamoyloxy)-1-methylpyridinium Bromide; Pyridostigmine (bromide); UNII-KVI301NA53; Piridostigmina bromuro [DCIT]; CCRIS 6798; HSDB 3924; 3-[(dimethylcarbamoyl)oxy]-1-methylpyridin-1-ium bromide; Pyridostigmini bromidum [INN-Latin]; EINECS 202-929-9; Ro 1-5130; Bromure de pyridostigmine [INN-French]; Pyridostigmini bromidum; Bromuro de piridostigmina [INN-Spanish
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

54 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Albendazole + Lefaxin DCVQ6UQ Albendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Auranofin + Lefaxin DC08NAV Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Benserazide + Lefaxin DCLRXEM Benserazide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BIO-300 + Lefaxin DCUH89O BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Brincidofovir + Lefaxin DCNNYO8 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diazoxide + Lefaxin DCUCAJC Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Lefaxin DCUMZI7 Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Epinephrine + Lefaxin DCAFEYH Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + Lefaxin DC2J4PP GS4071 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Imatinib + Lefaxin DCTIW5C Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Lefaxin DCSUZLV IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Itraconazole + Lefaxin DCFTPZ9 Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Pentostatin DC35SDY Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Gefitinib DCC6TN4 Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Acetazolamide DCRHVLE Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Dantrolene DCYTQ8C Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Diethylcarbamazine DC1OQOC Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Kanamycin DCZV3GJ Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Methotrexate DC2SM7Z Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Sivelestat DC6C989 Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Fomepizole DCKJWHD Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Triapine DCHX11J Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Everolimus DCKBULV Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Cinacalcet DCPKORF Cinacalcet Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Chlorzoxazone DCO13IK Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Docetaxel DCO5SO1 Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Arfolitixorin DCRE1JV Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + PF-02545920 DCJU5PY PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Tiagabine DCIJ5KI Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Oseltamivir DCSLF0Z Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Darunavir DCNLJL4 Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Bortezomib DC45EUS Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Methylene blue DCY0ICH Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Maprotiline DCMJ8VT Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Mycophenolic acid DC66P5W Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Mefloquine DC7EWLR Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Testolactone DCBRSLM Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Cerivastatin DCZURVM Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Metaxalone DCHNBFK Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Aciclovir DCYW2PV Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Cytarabine DCGCML3 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Cilostazol DCXXKSQ Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Lefaxin DCXTYVS Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Memantine + Lefaxin DCRJNM5 Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metyrosine + Lefaxin DCQVFXJ Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib + Lefaxin DC7QE7F Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PMID28460551-Compound-2 + Lefaxin DCK6UOP PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pramipexole + Lefaxin DCBD32P Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Probenecid + Lefaxin DCROF6W Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Quinine + Lefaxin DCT3DI9 Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Terameprocol + Lefaxin DCT3O9S Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testosterone + Lefaxin DCTEK4V Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triflupromazine + Lefaxin DC41MLS Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vorinostat + Lefaxin DCKHQ49 Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 54 DrugCom(s)

References

1 Novel approaches to the treatment of thrombosis. Trends Pharmacol Sci. 2002 Jan;23(1):25-32.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.