Details of the Drug Combinations

General Information of This Drug (ID: DM17ONX)

• Drug Name: Fexofenadine (DM17ONX)
• Synonyms: Carboxyterfenadine; Fexofendine; Terfenadine acid metabolite; Terfenadine carboxylate; F 9427; MDL 16455; Allegra (TN); Fastofen (TN); Fexofenadine (INN); Fexofenadine [INN:BAN]; Telfast (TN); Terfenadine-COOH; Terfenidine carboxylate, MDL 16455; Tilfur (TN); 2-[4-(1-hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropanoic acid; 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid; 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid

Indication

Allergic rhinitis; ICD 11: CA08.0; Status: Approved [1]; Seasonal allergic rhinitis; ICD 11: CA08.01; Status: Approved [2]

• Therapeutic Class: Antiallergic Agents
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Fexofenadine + Sulfasalazine	DC1E5J4	Sulfasalazine	Pharmacokinetics	[3]
Fexofenadine + Midazolam	DCRI0V4	Midazolam	Gout Flare	[4]
Fexofenadine + Montelukast	DCAVKH4	Montelukast	Allergic Rhinitis	[5]

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4819).
• [2] Fexofenadine FDA Label
• [3] ClinicalTrials.gov (NCT03012763) Oral Pharmacokinetics of Sulfasalazine, Paracetamol, Fexofenadine and Valsartan Using Different Administration Mediums
• [4] ClinicalTrials.gov (NCT03933007) Relation Between Blood Concentration of Colchicine and Response to Colchicine Treatment in Gout Flare
• [5] ClinicalTrials.gov (NCT02551536) Montelukast and Fexofenadine Versus Montelukast and Levocetrizine Combination in Allergic Rhinitis