Details of the Drug Combinations

General Information of This Drug (ID: DM1N62C)

Drug Name

Quetiapine DM1N62C

Synonyms

quetiapine; 111974-69-7; Quetiapine [INN:BAN]; UNII-BGL0JSY5SI; BGL0JSY5SI; CHEMBL716; 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol; CHEBI:8707; C21H25N3O2S; URKOMYMAXPYINW-UHFFFAOYSA-N; 2-(2-(4-Dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)ethanol; Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-; NCGC00095911-03; Co-Quetiapine; Norsic; Quetiapina; Quetiapinum; Quetiapine hemifumarate; Ketipinor (TN); Norsic (TN); Quetiapine (INN); Seroquel (Fumarate); Seroquel (TN); 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol; 2-{[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethyl]oxy}ethanol; PD-172760

Indication

Disease Entry	ICD 11	Status	REF
Anorexia nervosa cachexia	6B80	Approved	[1]
Bipolar depression	N.A.	Approved	[1]
Bipolar disorder	6A60	Approved	[1]
Bipolar I disorder	N.A.	Approved	[1]
Delirium	N.A.	Approved	[1]
Major depressive disorder	6A70.3	Approved	[1]
Methamphetamine dependence	6C46.2	Approved	[1]
Schizoaffective disorder	6A21	Approved	[1]
Schizophrenia	6A20	Approved	[2]
Alcohol dependence	6C40.2	Phase 3	[3]
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Therapeutic Class

Antipsychotic Agents

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

6 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Quetiapine + Aripiprazole	DCXCB60	Aripiprazole	Schizophrenia	[4]
Quetiapine + Paroxetine	DCF9I9G	Paroxetine	Combat Disorders	[5]
Quetiapine + Aripiprazole	DCR2A8B	Aripiprazole	Schizophrenia	[6]
Quetiapine + Risperidone	DCC5U45	Risperidone	Bipolar Disorder	[7]
Quetiapine + Risperidone	DCCGTQH	Risperidone	Schizophrenia	[8]
Sertraline + Quetiapine	DC542KP	Sertraline	Major Depressive Disorder With Psychotic Features	[9]
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References

1	Quetiapine FDA Label
2	The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22.
3	ClinicalTrials.gov (NCT02362412) Study to Evaluate the Effects of Switching Different Strength Forms of FK949E in Bipolar Disorder Patients With Major Depressive Episodes. U.S. National Institutes ofHealth.
4	ClinicalTrials.gov (NCT01164059) Clinical Effectiveness of Newer Antipsychotics in Comparison With Conventional Antipsychotics in Schizophrenia
5	ClinicalTrials.gov (NCT00292370) Quetiapine Augmentation for Treatment-resistant PTSD
6	ClinicalTrials.gov (NCT01129674) A Long-Term, Open-Label, Study on Schizophrenia
7	ClinicalTrials.gov (NCT02562287) Clozapine Versus Other Atypical Antipsychotics for Bipolar Disorder
8	ClinicalTrials.gov (NCT00423878) Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective Disorder
9	ClinicalTrials.gov (NCT00955474) Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms