Details of the Drug Combinations

General Information of This Drug (ID: DM1WYDU)

Drug Name

Uridine triacetate DM1WYDU

Synonyms

PN401

Indication

Disease Entry	ICD 11	Status	REF
Diabetic complication	5A2Y	Approved	[1]
Pancreatic cancer	2C10	Approved	[1]
Orotic aciduria	N.A.	Investigative	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Uridine triacetate + Idarubicin	DC3QGB7	Idarubicin	Glioblastoma? (Cell Line: T98G)	[3]
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1 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Uridine triacetate + Fludeoxyglucose F 18	DCNMK6Y	Fludeoxyglucose F 18	Brain Imaging	[4]
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References

1	ClinicalTrials.gov (NCT02110147) Open-Label Study of Uridine Triacetate in Pediatric Patients With Hereditary Orotic Aciduria. U.S. National Institutes of Health.
2	Uridine triacetate FDA Label
3	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4	ClinicalTrials.gov (NCT04417998) Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction