Details of the Drug Combinations

General Information of This Drug (ID: DM2ET1M)

Drug Name

Succinylcholine DM2ET1M

Synonyms

Anectine; Diacetylcholine; Ditilin; Ditiline; Listenon; Lysthenon; Quelicin; SCK; Succicuran; Succinocholine; Succinoylcholine; Succinylbischoline; Succinyldicholine; Sucostrin; Suxamethonium; Dicholine succinate; Succinyl choline; Anectine (TN); Scoline (TN); Succinic acid, diester with choline; Succinic acid, diester with choline chloride; Choline, succinate (ester); Choline, succinate (2:1) (ester); Trimethyl-[2-[4-oxo-4-(2-trimethylazaniumylethoxy)butanoyl]oxyethyl]azanium diio; Trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium; 2,2'-[(1,4-DIOXOBUTANE-1,4-DIYL)BIS(OXY)]BIS(N,N,N-TRIMETHYLETHANAMINIUM)

Indication

Disease Entry	ICD 11	Status	REF
Plasma cell myeloma	2A83.1	Approved	[1]
Spasm	MB47.3	Approved	[2]
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Therapeutic Class

Analgesics

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

4 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Succinylcholine + Rocuronium	DCHUHWE	Rocuronium	Neuromuscular Blockade	[3]
Succinylcholine + Propofol	DCVBKZ1	Propofol	Stroke	[4]
Succinylcholine + Vecuronium	DC8B0DI	Vecuronium	Anesthesia	[5]
Succinylcholine + Methohexital	DC074SV	Methohexital	Depression	[6]
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References

1	Succinylcholine FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4004).
3	ClinicalTrials.gov (NCT01441960) Optimal Dose of Succinylcholine and Rocuronium for Electroconvulsive Therapy (ECT)
4	ClinicalTrials.gov (NCT02822144) General Anesthesia Versus Sedation During Intra-arterial Treatment for Stroke
5	ClinicalTrials.gov (NCT02237443) Mask Ventilation Before and After Neuromuscular Blockade
6	ClinicalTrials.gov (NCT01907217) Enhancing the Effectiveness of Electroconvulsive Therapy in Severe Depression