Details of the Drug Combinations

General Information of This Drug (ID: DM2NQUY)

• Drug Name: Indocyanine green (DM2NQUY)
• Synonyms: indocyanine green; Cardiogreen; 3599-32-4; AC1L2DMU; GTPL4844; KS-00000YFZ; MOLI001001; F9995-0163; sodium 4-(2-((1E,3E,5E,7E)-7-(1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-2(3H)-ylidene)hepta-1,3,5-trienyl)-1,1-dimethyl-1H-benzo[e]indolium-3-yl)butane-1-sulfonate; sodium 4-[2-[(1E,3E,5E,7Z)-7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-2-ylidene]hepta-1,3,5-trienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]butane-1-sulfonate; sodium 4-[2-[7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-3-ium-2-yl]hepta-2,4

Indication

Gastrointestinal disease; ICD 11: DE2Z; Status: Approved [1]

• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

7 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Indocyanine green + Guanosine-5'-Monophosphate	DC0XZK2	Guanosine-5'-Monophosphate	Gastrointestinal Diseases	[2]
Indocyanine green + Isosulfan blue	DC8IOOF	Isosulfan blue	Recurrent Melanoma	[3]
Indocyanine green + Isosulfan blue	DCCY3JR	Isosulfan blue	Endometrial Cancer	[4]
Indocyanine green + Methylene blue	DCOVE4I	Methylene blue	Lymphedema	[5]
Indocyanine green + Aflibercept	DCPQ3TA	Aflibercept	Polypoidal Choroidal Vasculopathy	[6]
Indocyanine green + Methylene blue	DCXPURP	Methylene blue	Sentinel Lymph Node	[7]
Indocyanine green + Lidocaine	DCCZGAQ	Lidocaine	Lung Cancer	[8]

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4844).
• [2] ClinicalTrials.gov (NCT01034670) Advanced Gastrointestinal Endoscopic Imaging
• [3] ClinicalTrials.gov (NCT01898403) Lymph Node Mapping Using Indocyanine Green Solution in Diagnosing Patients With Malignant Melanoma
• [4] ClinicalTrials.gov (NCT01818739) Lymph Node Mapping in Patients With Endometrial Cancer
• [5] ClinicalTrials.gov (NCT01276054) Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients.
• [6] ClinicalTrials.gov (NCT02597855) Short-term Efficacy of Intravitreal Afilibercept Depending on Subtypes of Polypoidal Choroidal Vasculopathy: Polypoidal Choroidal Neovascularization or Idiopathic Choroidal Vasculopathy
• [7] ClinicalTrials.gov (NCT02084784) Application of Surgical Navigation System in Sentinel Lymph Node of Breast Cancer Research
• [8] ClinicalTrials.gov (NCT00540982) Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction