Details of the Drug Combinations

General Information of This Drug (ID: DM3NMT6)

Drug Name

Articaine DM3NMT6

Synonyms

Articaine; Carticaine; 23964-58-1; Articaine [INN:BAN]; Articainum [INN-Latin]; Articaina [INN-Spanish]; Hoe-045; Ultracain; HOE 045; methyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate; methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate; Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat); Q-200652; Articainum; Articaina; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid, methyl ester; 2-Thiophenecarboxylicacid, 4-methyl-3-[[1-oxo-2-(propylamino)propy

Indication

Disease Entry	ICD 11	Status	REF
Anaesthesia	9A78.6	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Articaine + Mepivacaine	DC7SUJP	Mepivacaine	Symptomatic Irreversible Pulpitis	[2]
Epinephrine + Articaine	DCN6P7U	Epinephrine	Irreversible Pulpitis	[3]
Articaine + Benzocaine	DCAUZ28	Benzocaine	Anesthesia of Mucous Membrane	[4]
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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	ClinicalTrials.gov (NCT03725579) Anesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine
3	ClinicalTrials.gov (NCT02807298) 4% Articaine and 2% Lidocaine by Intraligamentary Technique in Irreversible Pulpitis
4	ClinicalTrials.gov (NCT01951820) Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis