Details of the Drug Combinations

General Information of This Drug (ID: DM3XNUI)

Drug Name

Tazobactam DM3XNUI

Synonyms

TAZ; CL298741; YTR830H; CL-298741; Piprataz (TN); YTR-830H; Tazobactam (JAN/USAN/INN); (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4; (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide

Indication

Disease Entry	ICD 11	Status	REF
Appendicitis	DB10	Approved	[1]
Bacterial infection	1A00-1C4Z	Approved	[2]
Peritonitis	N.A.	Approved	[1]
Staphylococcus aureus infection	N.A.	Approved	[1]
Pelvic inflammatory disease	GA05	Investigative	[1]
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Therapeutic Class

Antiinfective Agents

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Tazobactam + Ceftolozane sulfate	DCN8W39	Ceftolozane sulfate	Other Infectious Diseases	[3]
Linezolid + Tazobactam	DCZ9CJN	Linezolid	Bacterial Pneumonia	[4]
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References

1	Tazobactam FDA Label
2	Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
3	ClinicalTrials.gov (NCT03485950) Comparative Study To Determine The Efficacy, Safety, And Tolerability Of Ceftolozane-Tazobactam
4	ClinicalTrials.gov (NCT02493764) Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014)