Details of the Drug Combinations

General Information of This Drug (ID: DM53BDW)

Drug Name
Trioxsalen   DM53BDW
Synonyms
trioxsalen; 3902-71-4; Trioxysalen; Trisoralen; Trimethylpsoralen; 4,5',8-Trimethylpsoralen; Elder 8011; Trioxysalenum; Trioxisaleno; Trioxysalene; 2',4,8-Trimethylpsoralen; 4,5',8-Trimethylpsoralene; NSC-71047; 2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one; UNII-Y6UY8OV51T; Trioxysalene [INN-French]; Trioxysalenum [INN-Latin]; NSC71047; Trioxisaleno [INN-Spanish]; NSC 71047; TRIOXSALIN; 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-; EINECS 223-459-0; 4,8,5'-Trimethylpsoralen; BRN 0221723; Y6UY8OV51T
Indication
Disease Entry ICD 11 Status REF
Skin sensitivity to sun N.A. Approved [1]
Vitiligo ED63.0 Approved [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

55 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Trioxsalen DCIOJF0 Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Brincidofovir + Trioxsalen DCIIWGU Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cytarabine + Trioxsalen DCEREIC Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diphenidol + Trioxsalen DCAXOSW Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dronedarone + Trioxsalen DC3G1R2 Dronedarone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Flavonoid derivative 1 + Trioxsalen DCZEV27 Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Imatinib + Trioxsalen DCCKTMP Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
JZL195 + Trioxsalen DCL6IQR JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Kanamycin + Trioxsalen DCH4ABI Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Lacosamide + Trioxsalen DCQPGI1 Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Leflunomide + Trioxsalen DC8EX02 Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Trioxsalen DCAUENM Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
LY03004 + Trioxsalen DC8Q7XZ LY03004 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mefloquine + Trioxsalen DC0BU5H Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metaxalone + Trioxsalen DCHR5XR Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Trioxsalen DCSED02 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PF-02545920 + Trioxsalen DCM3ADX PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Probenecid + Trioxsalen DCX4VG3 Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Quinine + Trioxsalen DCYLW3U Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Silver sulfadiazine + Trioxsalen DC2T79V Silver sulfadiazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triapine + Trioxsalen DCXBJNN Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Trioxsalen + Pentostatin DCMOM7O Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Gefitinib DCQK3SO Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Ruxolitinib DC6SV0N Ruxolitinib Hodgkin lymphoma (Cell Line: L-1236) [3]
Trioxsalen + Citalopram DCGJJN7 Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Panobinostat DCBTI9J Panobinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Trioxsalen + Methotrexate DC1602X Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + IT-141 DCIVRWB IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Methylergonovine DCMZRIH Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Metyrosine DCYBFW1 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Terameprocol DCZS0N0 Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Itraconazole DCDXWDO Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Fluspirilene DCYMLQY Fluspirilene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Ciprofibrate DC4EAB1 Ciprofibrate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Dichlorphenamide DCJZ8JP Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Diphenidol DCXNWCR Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + BIO-300 DCC6XU7 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Etonogestrel DC5UDT0 Etonogestrel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Oseltamivir DC1M11M Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Idarubicin DCKX7GV Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Linagliptin DCO89I3 Linagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Bortezomib DC7KT5P Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Methylene blue DCLCQN1 Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Valproic Acid DCVJBT7 Valproic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Sorafenib DCWX3FK Sorafenib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Mycophenolic acid DCZ2MUZ Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Doxorubicin DCHWLSD Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Olmesartan medoxomil DCKKU2Y Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Auranofin DCRB17R Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Rufinamide DCW0K9T Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Cerivastatin DCX9A9G Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Atovaquone DCZJRPL Atovaquone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Aciclovir DCPRAAY Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + GSK2194069 DC9A7LA GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vinblastine + Trioxsalen DCHC4OI Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
------------------------------------------------------------------------------------
⏷ Show the Full List of 55 DrugCom(s)

References

1 Trioxsalen FDA Label
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.