Details of the Drug Combinations

General Information of This Drug (ID: DM6HXTS)

Drug Name
Anamorelin   DM6HXTS
Synonyms
249921-19-5; UNII-DD5RBA1NKF; DD5RBA1NKF; RC 1291; Anamorelin [INN]; ONO-7643; SCHEMBL935751; CHEMBL2110579; EX-A154; DTXSID20179702; C31H42N6O3; BCP06108; 3444AH; ZINC43130908; AKOS030526752; SB16911; API0008642; RC-1291; NCGC00378854-01; KB-80338; HY-14734; BC600755; (3R)-1-(2-Methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide; AB0165721; FT-0773543; W-5500; 921A195; CS 1036
Indication
Disease Entry ICD 11 Status REF
Carbohydrate metabolism disorder 5C51.Z Phase 3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

91 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Anamorelin DCVFNNJ Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohydroxamic Acid + Anamorelin DCBX3LK Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Aprepitant DC8HP6G Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Mebutamate DC4YTBR Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Picoplatin DCZLF00 Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Baclofen DCB0BEA Baclofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Acetazolamide DCYPL6E Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Dantrolene DC12GVL Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Diethylcarbamazine DCWL6RN Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Citalopram DCTFMCB Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + PMID28460551-Compound-2 DC06URR PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Panobinostat DC1PIV2 Panobinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
Anamorelin + Vinblastine DCO6DG3 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Triapine DC8IC3C Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Everolimus DCVSWVO Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + IT-141 DCVGT4Y IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Chlorzoxazone DCZ70Q7 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Memantine DCICLPQ Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + ETHISTERONE DCY6JDX ETHISTERONE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Galantamine DCDXJ5I Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Phensuximide DCAISCK Phensuximide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Fluspirilene DCCG7BX Fluspirilene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Dichlorphenamide DCP1B28 Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Niclosamide DCQ81YX Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + PF-02545920 DC6DV66 PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + GINKGOLIDE A DCY8HFX GINKGOLIDE A Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Allopurinol DC300KB Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Idarubicin DCAXLP3 Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Methocarbamol DCUR0U0 Methocarbamol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Bortezomib DCDQOS4 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Leflunomide DC254P8 Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Novobiocin DCMCD93 Novobiocin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Chlorambucil DCAXTZG Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Brincidofovir DCS8LGC Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Asenapine DC7RJXC Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Endoxifen DC0T668 Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Mycophenolic acid DCPOPNS Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Lacosamide DCFOVG0 Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Auranofin DC8VWWT Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Vorinostat DCAK7MB Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Hydroxychloroquine DC47ZO6 Hydroxychloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + ML323 DCPW8RH ML323 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Aciclovir DCHIGHJ Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Tacrolimus DCD2DGU Tacrolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Armodafinil + Anamorelin DCG3T1X Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Artemisinin + Anamorelin DC09RRB Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Asenapine + Anamorelin DCCOTL2 Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BIO-300 + Anamorelin DCVWGS0 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Busulfan + Anamorelin DCJ3Q58 Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cerivastatin + Anamorelin DCM4GV3 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlorphenesin + Anamorelin DC72DPL Chlorphenesin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cisatracurium + Anamorelin DCT1JWU Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Clopidogrel + Anamorelin DCP0FCA Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Darunavir + Anamorelin DCS8SEX Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Anamorelin DC2APXH Desoxycorticosterone pivalate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diazoxide + Anamorelin DCT7XBW Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Eflornithine + Anamorelin DCM68XL Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Anamorelin DCIZGD1 Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Enoxacin + Anamorelin DC55IMS Enoxacin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Flavonoid derivative 1 + Anamorelin DCW2ZFY Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fomepizole + Anamorelin DC7SFB8 Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Gefitinib + Anamorelin DCW53LP Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hydralazine + Anamorelin DCGIY3A Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hyodeoxycholic acid + Anamorelin DC7MKHI Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Itraconazole + Anamorelin DC3Z5BB Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Kanamycin + Anamorelin DCC9RWX Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Anamorelin DCVUJSJ L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lacosamide + Anamorelin DC81SCR Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Linagliptin + Anamorelin DCD1IXQ Linagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lithium Citrate + Anamorelin DC2OSR6 Lithium Citrate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lubiprostone + Anamorelin DCFSX7N Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
LY03004 + Anamorelin DCC5ANJ LY03004 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + Anamorelin DCAFIOJ Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mebutamate + Anamorelin DCTZ0TP Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mefloquine + Anamorelin DC0WCGZ Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metaxalone + Anamorelin DC44YX5 Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Miglustat + Anamorelin DCK4AL5 Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Anamorelin DCP4TI6 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Palonosetron + Anamorelin DC6XQ6L Palonosetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentostatin + Anamorelin DCURQZQ Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pepstatin + Anamorelin DCTMWGB Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PHA-739358 + Anamorelin DCUPH3G PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pomalidomide + Anamorelin DC8IL6D Pomalidomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pyrazinamide + Anamorelin DCL028O Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Repaglinide + Anamorelin DC0YF6R Repaglinide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
SCH 727965 + Anamorelin DCETO9M SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sivelestat + Anamorelin DCPG6OH Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Teriflunomide + Anamorelin DC3O2J5 Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testosterone + Anamorelin DCIL1N1 Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triflupromazine + Anamorelin DCHJ1YI Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triiodothyronine + Anamorelin DCUIWZJ Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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References

1 ClinicalTrials.gov (NCT01395914) Anamorelin HCl in the Treatment of Non-Small Cell Lung Cancer-Cachexia (NSCLC-C): An Extension Study (ROMANA 3). U.S. National Institutes of Health.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.