Details of the Drug Combinations

General Information of This Drug (ID: DM8JRH0)

Drug Name

Cangrelor DM8JRH0

Synonyms

Cangrelor; 163706-06-7; Kengreal; UNII-6AQ1Y404U7; AR-C69931XX; CHEMBL334966; 6AQ1Y404U7; kengrexal; 5'-O-[({[dichloro(phosphono)methyl](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]-N-[2-(methylsulfanyl)ethyl]-2-[(3,3,3-trifluoropropyl)sulfanyl]adenosine; 5'-Adenylicacid,N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-,anhydridewithP,P'-(dichloromethylene)bis[phosphonicacid](1:1)

Indication

Disease Entry	ICD 11	Status	REF
Thrombosis	DB61-GB90	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Cangrelor + Brilinta	DC3BWX5	Brilinta	Coronary Artery Disease	[2]
Cangrelor + Clopidogrel	DC7GMFR	Clopidogrel	Coronary Artery Disease (CAD)	[3]
Prasugrel + Cangrelor	DC56HU0	Prasugrel	Coronary Artery Disease	[4]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1776).
2	ClinicalTrials.gov (NCT01766466) Cangrelor Ticagrelor Transition Study
3	ClinicalTrials.gov (NCT01979445) Cangrelor to Clopidogrel or Prasugrel Transition Study
4	ClinicalTrials.gov (NCT01852019) Cangrelor Prasugrel Transition Study