Details of the Drug Combinations

General Information of This Drug (ID: DMBEX4O)

Drug Name
Methylergonovine   DMBEX4O
Synonyms
Basofortina; Ergotyl; Metenarin; Methergen; Methergin; Methergine; Methylergobasin; Methylergobasine; Methylergobrevin; Methylergometrin; Methylergometrine; Methylergometrinum; Methylergonovin; Metilergometrina; Metilergometrinio; Partergin; Ryegonovin; Lysergic acid butanolamide; Methylergometrine maleate; Metilergometrina [DCIT]; ME 277; Ergotyl (TN); Methergine (TN); Methylergometrine (INN); Methylergometrine [INN:BAN]; Methylergometrinum [INN-Latin]; Metilergometrinio [INN-Spanish]; Spametrin-M; D-Lysergic acid-dl-hydroxybutylamide-2; N-(alpha-(Hydroxymethyl)propyl)-D-lysergamide; D-Lysergic acid-(+)-butanolamide-(2); (8beta)-N-[(1S)-1-(hydroxymethyl)propyl]-6-methyl-9,10-didehydroergoline-8-carboxamide; 9,10-Didehydro-N-(1-(hydroxymethyl)propyl)-6-methylergoline-8-carboxamide; 9,10-Didehydro-N-(alpha-(hydroxymethyl)propyl)-6-methyl-ergoline-8-beta-carboxamide
Indication
Disease Entry ICD 11 Status REF
Spontaneous abortion JA00.0 Approved [1]
Therapeutic Class
Oxytocics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

64 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Aciclovir + Methylergonovine DCRQ4CR Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Amantadine + Methylergonovine DCLCL85 Amantadine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Asenapine + Methylergonovine DCA0PF3 Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + Methylergonovine DC5EPS8 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BRL-15572 + Methylergonovine DCSCJ8B BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cerivastatin + Methylergonovine DCVPTLQ Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dactinomycin + Methylergonovine DCVOSBQ Dactinomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dantrolene + Methylergonovine DCV9UMZ Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Darunavir + Methylergonovine DC7M0TP Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Methylergonovine DCY7HQO Desoxycorticosterone pivalate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Methylergonovine DCQPXEN Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Enalaprilat + Methylergonovine DCOAKLH Enalaprilat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Endoxifen + Methylergonovine DCJZYTY Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Eptifibatide + Methylergonovine DC57ZXC Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fibrates + Methylergonovine DCGZULH Fibrates Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Gefitinib + Methylergonovine DC3W1C4 Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Imatinib + Methylergonovine DCC079E Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Methylergonovine DCBF3NN IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
JZL195 + Methylergonovine DC69OAG JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lubiprostone + Methylergonovine DCPSP9E Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + Methylergonovine DCU442B Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mebutamate + Methylergonovine DC3P62W Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Triiodothyronine DCXSQ2M Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Diethylcarbamazine DC5VE5R Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Kanamycin DCV64DZ Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Tacrine DC55ZGR Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Vinblastine DCFUQRS Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Fomepizole DCK34N5 Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Triapine DC6T8Q3 Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Everolimus DCBEEB7 Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + 10-hydroxycamptothecin DC309C1 10-hydroxycamptothecin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Docetaxel DCGU56G Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Ginsenoside Rb1 DCXQVVX Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Clopidogrel DCGZVX6 Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Triflupromazine DCFZ760 Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Niclosamide DCK979J Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Tiagabine DCRIR4Q Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Oseltamivir DCNINON Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Diazoxide DCCPQUJ Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Allopurinol DCSMV7S Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Idarubicin DCU04LX Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Maprotiline DCODE5S Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Quinine DCP7PKD Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Mycophenolic acid DCX0VY2 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Cisatracurium DCG4WAR Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Testolactone DCDU6IQ Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + PMID28870136-Compound-43 DCFAA5X PMID28870136-Compound-43 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + FORMESTANE DCQX7RC FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylergonovine + Estramustine DCPHM0E Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Methylergonovine DC8GBQT Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Nabilone + Methylergonovine DC51QKM Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PF-02545920 + Methylergonovine DCKYORE PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PMID28460551-Compound-2 + Methylergonovine DC6X7JC PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Probenecid + Methylergonovine DCZO3EF Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Procarbazine + Methylergonovine DC5SO63 Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pyrazinamide + Methylergonovine DCXJR1A Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sertraline + Methylergonovine DCPLHTT Sertraline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Silver sulfadiazine + Methylergonovine DCGKXD6 Silver sulfadiazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sivelestat + Methylergonovine DCFQN9W Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Terameprocol + Methylergonovine DC09H55 Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testosterone + Methylergonovine DCUAOEG Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Topotecan + Methylergonovine DCWXDA2 Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trioxsalen + Methylergonovine DCMZRIH Trioxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
WAY-100635 + Methylergonovine DC1P2KG WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 64 DrugCom(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.