Details of the Drug Combinations

General Information of This Drug (ID: DMCEW64)

Drug Name
Ceftriaxone   DMCEW64
Synonyms
Biotrakson; CTRX; Cefatriaxone; Ceftriaxon; Ceftriaxona; Ceftriaxonum; Ceftriazone; Longacef; Longaceph; Rocefin; Rocephin; Rocephine; CEFTRIAXONE SODIUM; Ceftriaxone intravenous; Ro 139904; Ceftriaxona [INN-Spanish]; Ceftriaxone (INN); Ceftriaxone (TN); Ceftriaxone [USAN:JAN]; Ceftriaxone, Disodium Salt; Ceftriaxonum [INN-Latin]; DRG-0071; Ro13-9904; Rocephin (TN); Ceftriaxone, Disodium Salt, Hemiheptahydrate; Ro-13-9904; (6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-(O-methyloxime), sesquaterhydrate; (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(methyloxy)imino]acetyl}amino)-3-{[(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid
Indication
Disease Entry ICD 11 Status REF
Acute gonococcal cervicitis N.A. Approved [1]
Bacteremia 1A73 Approved [1]
Bacterial arthritis N.A. Approved [1]
Bacterial infection 1A00-1C4Z Approved [2]
Chancroid N.A. Approved [1]
Endometritis N.A. Approved [1]
Escherichia coli meningitis N.A. Approved [1]
Gonococcal infection of joint N.A. Approved [1]
Meningococcal meningitis N.A. Approved [1]
Pneumococcal meningitis N.A. Approved [1]
Staphylococcal pneumonia N.A. Approved [1]
Pelvic inflammatory disease GA05 Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

16 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Ceftriaxone + Azithromycin DC54EZM Azithromycin Chlamydia [3]
Ceftriaxone + Metronidazole DCA1P3K Metronidazole Infection [4]
Ceftriaxone + Octreotide DCDHZFS Octreotide Variceal Hemorrhage [5]
Ciprofloxacin XR + Ceftriaxone DC4Z8NL Ciprofloxacin XR Gonococcal Infection [6]
Ciprofloxacin XR + Ceftriaxone DCIKDQ8 Ciprofloxacin XR Gonococcal Infection [7]
Ertapenem + Ceftriaxone DC8ZPFF Ertapenem Liver Abscess, Pyogenic [8]
Ceftriaxone + Metronidazole DCQKGTL Metronidazole Ulcerative Colitis [9]
Ciprofloxacin XR + Ceftriaxone DCA04R0 Ciprofloxacin XR Gonorrhea Male [10]
Doxycycline + Ceftriaxone DCKWPHW Doxycycline Pelvic Inflammatory Disease [11]
Propranolol + Ceftriaxone DCXUVAW Propranolol Stroke [12]
Ceftriaxone + Hydrocortisone DCCOFAU Hydrocortisone Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit [13]
Ceftriaxone + Azithromycin DCO5GSI Azithromycin Uncomplicated Urogenital Gonorrhea [14]
Ceftriaxone + Azithromycin DCIWS8I Azithromycin Community-Acquired Pneumonia (CAP) [15]
Ceftriaxone + Levofloxacin DCPR2ZA Levofloxacin Cholangitis [16]
Doxycycline + Ceftriaxone DCY6CED Doxycycline Early Syphilis [17]
Vancomycin + Ceftriaxone DCOPY0X Vancomycin Nephrolithiasis [18]
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⏷ Show the Full List of 16 DrugCom(s)

References

1 Ceftriaxone FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5326).
3 ClinicalTrials.gov (NCT01150747) Chlamydia Trachomatis Immunology and Vaccinology Study
4 ClinicalTrials.gov (NCT01254344) Efficacy and Safety of Ertapenem Sodium (MK-0826) Following Colorectal Surgery in Chinese Adults (MK-0826-056)
5 ClinicalTrials.gov (NCT03061604) RCT to Determine the Efficacy of Combining Hemospray With Medical Treatment in Acute Variceal Bleeding
6 ClinicalTrials.gov (NCT04870138) Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)
7 ClinicalTrials.gov (NCT03840811) Experimental Human Infection With Neisseria Gonorrhoeae
8 ClinicalTrials.gov (NCT01723150) Antibiotics for Klebsiella Liver Abscess Study
9 ClinicalTrials.gov (NCT03794765) Antibiotics as an Adjuvant in Patients With Acute Severe Ulcerative Colitis
10 ClinicalTrials.gov (NCT05294588) Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae
11 ClinicalTrials.gov (NCT01160640) The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID)
12 ClinicalTrials.gov (NCT05375240) Propranolol on Post Stroke Immune Status and Infection
13 ClinicalTrials.gov (NCT02473263) Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock
14 ClinicalTrials.gov (NCT02210325) Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea
15 ClinicalTrials.gov (NCT00035347) Intravenous Azithromycin Plus Intravenous Ceftriaxone Followed by Oral Azithromycin With Intravenous Levofloxacin Followed by Oral Levofloxacin for the Treatment of Moderate to Severely Ill Hospitalized Patients With Community Acquired Pneumonia
16 ClinicalTrials.gov (NCT03087656) Antibiotics to Decrease Post ERCP Cholangitis
17 ClinicalTrials.gov (NCT05980871) Treatment Responses of Early Syphilis to Ceftriaxone Plus Doxycycline
18 ClinicalTrials.gov (NCT02384200) A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])