Details of the Drug Combinations

General Information of This Drug (ID: DMCY0TI)

Drug Name
Carglumic acid   DMCY0TI
Synonyms Carbaglu (TN)
Indication
Disease Entry ICD 11 Status REF
Acute hyperammonaemia 5C50.A Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

59 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Carglumic acid DC43UYP Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acarbose + Carglumic acid DCGUA58 Acarbose Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Asenapine + Carglumic acid DCWJKO5 Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Baclofen + Carglumic acid DCWUJHZ Baclofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Primidone DCHV97O Primidone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Acetazolamide DCVUTS0 Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Diethylcarbamazine DCXVNZ7 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Kanamycin DCMNF6E Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Chlorphenesin DCUWDL2 Chlorphenesin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Vinblastine DC5A8BK Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Everolimus DCA9FYF Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Pepstatin DCN8YF9 Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Metyrosine DCJ5U2X Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Testosterone cypionate DC12439 Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Flavonoid derivative 1 DC4R5DC Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Itraconazole DCZORZS Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Emetine DC4TZWT Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Armodafinil DCDXIZS Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Diazoxide DC4PDFT Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Tamoxifen DCYMLLV Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Idarubicin DCGFJMU Idarubicin Glioblastoma? (Cell Line: T98G) [2]
Carglumic acid + Imatinib DC9SNVG Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Methylene blue DCJ1M9V Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Trimethobenzamide DCELRMZ Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Oxyphenbutazone DCDNVG7 Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Leflunomide DCZO0G2 Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Brincidofovir DCXZTDY Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Quinine DC1C7ES Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Mycophenolic acid DCU5FVL Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Doxorubicin DC4O5X5 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Auranofin DCN4WC4 Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Vorinostat DCGNYCZ Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Cerivastatin DCUSJHJ Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Raltegravir DCZTQOE Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Azatadine DCJAFRU Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cinacalcet + Carglumic acid DCQGKK4 Cinacalcet Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cisatracurium + Carglumic acid DC3JXQM Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + Carglumic acid DC9B3D1 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Carglumic acid DCR7P02 Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diethylcarbamazine + Carglumic acid DC6K6DE Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Epinephrine + Carglumic acid DCBSK49 Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Gefitinib + Carglumic acid DC4BZUF Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hydralazine + Carglumic acid DCY9J0G Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Isosorbide dinitrate + Carglumic acid DCVGSOY Isosorbide dinitrate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Carglumic acid DC2RZJV IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Carglumic acid DCR1PLE Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lubiprostone + Carglumic acid DCD782Q Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mefloquine + Carglumic acid DC60FAW Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Memantine + Carglumic acid DCCB4IK Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Naltrexone + Carglumic acid DCP3QOS Naltrexone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Niclosamide + Carglumic acid DCY5RIK Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Oseltamivir + Carglumic acid DCNGHA7 Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pargyline + Carglumic acid DCAEQ7E Pargyline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Phenprocoumon + Carglumic acid DCBJS8S Phenprocoumon Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Procarbazine + Carglumic acid DCIDY1R Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ribavirin-TP + Carglumic acid DCI6ZQE Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sivelestat + Carglumic acid DCZJXGD Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Spironolactone + Carglumic acid DCKP3TD Spironolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triflupromazine + Carglumic acid DCE762U Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 59 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7458).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.