Details of the Drug Combinations

General Information of This Drug (ID: DMDXRP1)

Drug Name
ETHISTERONE   DMDXRP1
Synonyms
17-Hydroxypregn-4-en-20-yn-3-one; Syngestrotabs; Aethisteron; Progestolets; Pregneninolone; Progestoral; Gestoral; Ethinone; Colutoid; Trosinone; Prolutol; Progestab; Produxan; Nalutoral; Prodroxan; Prodoxan; Nugestoral; Pregnin; Prone; Lucorteum Oral; Lutidon Oral; Progestin P; Proluton C; Primolut C; Ora-Lutin; Ethinyltestosterone; Anhydroxyprogesterone; 17.alpha.-Ethynyltestosterone; Anhydrohydroxyprogesterone; Ethynyltestosterone; Testosterone, 17-ethynyl-; NSC-9565; 17-Ethinyltestosterone; 17.alpha.-Pregn-4-en-20-yn-3-one, 17-hydroxy-
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

59 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + ETHISTERONE DCS09R3 Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acitretin + ETHISTERONE DCK21CK Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + ETHISTERONE DCY6JDX Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aprepitant + ETHISTERONE DC1BL8I Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Arfolitixorin + ETHISTERONE DCGKST6 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Artemisinin + ETHISTERONE DCOUR44 Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + ETHISTERONE DCURW11 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlorphenesin + ETHISTERONE DCD377A Chlorphenesin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cisatracurium + ETHISTERONE DCEHSI7 Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + ETHISTERONE DC3T257 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Gefitinib DC5MIEK Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Acetazolamide DCVYTVH Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Diethylcarbamazine DCXN3C2 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Kanamycin DC7D3J2 Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + PMID28460551-Compound-2 DC38SHE PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Fomepizole DCT602M Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Rifampin DCII706 Rifampin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + IT-141 DC3FAQO IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Chlorzoxazone DC4674S Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Docetaxel DC05NBI Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Phensuximide DCY0E29 Phensuximide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Armodafinil DCA6CNB Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Sitagliptin DC7NXO1 Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + BIO-300 DCBHH3K BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Niclosamide DC2HELJ Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Isoproterenol DCU82SH Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Diazoxide DCIO1QI Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Allopurinol DCA0NIK Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Idarubicin DCT30BQ Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Imatinib DCGLF4J Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Darunavir DCJZVFX Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Pramipexole DC512CZ Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Methylene blue DCVC7OC Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Mebendazole DCY97ZX Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Clascoterone DCNXCQJ Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Cefmenoxime DCA0JQX Cefmenoxime Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Enalaprilat DC0XAFK Enalaprilat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Oxyphenbutazone DC7H0F2 Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Leflunomide DCBSZ9A Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Brincidofovir DCUYG51 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Endoxifen DC4Z1UU Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Iloprost DCFWX2V Iloprost Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Testolactone DCUHC6H Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Auranofin DCJL2YV Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Cerivastatin DC3OMGJ Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Aciclovir DCDEEUP Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Raltegravir DC3YWDQ Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Guanfacine + ETHISTERONE DCGPHS1 Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + ETHISTERONE DC230RT Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Loperamide + ETHISTERONE DCSV7TG Loperamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mefloquine + ETHISTERONE DCWTLTM Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metaxalone + ETHISTERONE DCN3SBR Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metyrosine + ETHISTERONE DC8SWAE Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Nabilone + ETHISTERONE DC2NGXB Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sumatriptan + ETHISTERONE DC53FC5 Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tamoxifen + ETHISTERONE DC5S3YW Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triapine + ETHISTERONE DCUA2DL Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vinblastine + ETHISTERONE DCLKIA8 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vorinostat + ETHISTERONE DC902TK Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 59 DrugCom(s)

References

1 TOMOCOMD-CARDD descriptors-based virtual screening of tyrosinase inhibitors: evaluation of different classification model combinations using bond-b... Bioorg Med Chem. 2007 Feb 1;15(3):1483-503.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.