General Information of This Drug (ID: DME8FZ9)

Drug Name
Methoxsalen   DME8FZ9
Synonyms
Ammodin; Ammoidin; Deltasoralen; Dermox; Geroxalen; Meladinin; Meladinina; Meladinine; Meladoxen; Meloxine; Methoxalen; Methoxaten; Oxoralen; Oxsoralen; Oxypsoralen; Puvalen; Puvamet; Ultramop; Uvadex; XANTHOTOXIN; Xanthotoxine; Zanthotoxin; Boehringer Ingelheim Brand of Methoxsalen; Canderm Brand of Methoxsalen; Chinoin Brand of Methoxsalen; DB Brand of Methoxsalen; Delta Brand of Methoxsalen; Dermatech Brand of Methoxsalen; Galderma Brand of Methoxsalen; Methoxa Dome; Methoxsalen Canderm Brand; Methoxsalen Chinoin Brand; Methoxsalen Delta Brand; Methoxsalen Dermatech Brand; Methoxsalen plus ultraviolet radiation; Mex America Brand of Methoxsalen; Oxsoralen Ul tra; Oxsoralen Ultra; Oxsoralen lotion; Sanofi Synthelabo Brand of Methoxsalen; Ultra Mop; Ultramop Lotion; ICN Brand 1 of Methoxsalen; ICN Brand 2 of Methoxsalen; ICN Brand 3 of Methoxsalen; X0009; An 8-methoxyfurocoumarin; Meladinin (VAN); Methoxa-Dome; Methoxsalen Mex-America Brand; Methoxsalen Sanofi-Synthelabo Brand; Methoxsalen [BAN:JAN]; Methoxsalen with ultra-violet A theraphy; Mex-America Brand of Methoxsalen; New-Meladinin; O-methylxanthotoxol; OXSORALEN (TN); Oxsoralen (TN); Oxsoralen-ultra; Proralone-mop; Psoralen-mop; Psoralon-MOP; Sanofi-Synthelabo Brand of Methoxsalen; Methoxsalen (JP15/USP); Methoxy-8-psoralen; 5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, .delta.-lactone; 5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, delta-lactone; 6-Hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone; 7-Furocoumarin; 8 Methoxypsoralen; 8-METHOXYPSORALEN + UVA (SEE ALSO C55903); 8-MOP; 8-Methoxy; 8-Methoxy(furano-3'.2':6.7-coumarin); 8-Methoxy-(furano-3'.2':6.7-coumarin); 8-Methoxy-2',3',6,7-furocoumarin; 8-Methoxy-4',5',6,7-furocoumarin; 8-Methoxy-4',5':6,7-furocoumarin; 8-Methoxy-[furano-3'.2':6.7-coumarin]; 8-Methoxyfuranocoumarin; 8-Methoxypsoralen; 8-Methoxypsoralen with ultraviolet A therapy; 8-Methoxypsoralene; 8-methoxyfuranocoumarins; 8-methoxyfurocoumarins; 8MO; 8MOP; 9-(methyloxy)-7H-furo[3,2-g]chromen-7-one; 9-Methoxy-7H-furo(3,2-g)(1)benzopyran-7-one; 9-Methoxy-7H-furo(3,2-g)benzopyran-7-one; 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 9-Methoxy-7H-furo[3,2-g]chromen-7-one; 9-Methoxyfuro(3,2-g)chromen-7-one; 9-Methoxyfuro[3,2-g][1]benzopyran-7-one; 9-Methoxypsoralen; 9-metho xy-7H-furo(3,2-g)benzopyran-7-one; 9-methoxyfuro[3,2-g]chromen-7-one
Indication
Disease Entry ICD 11 Status REF
Cutaneous T-cell lymphoma 2B01 Approved [1]
Primary cutaneous T-cell lymphoma N.A. Approved [2]
Psoriasis vulgaris EA90 Approved [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

47 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Methoxsalen DC6NEP0 Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Artemisinin + Methoxsalen DCV83IG Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Asenapine + Methoxsalen DCCKI64 Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
BIO-300 + Methoxsalen DCAZCK5 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Brincidofovir + Methoxsalen DCGI40J Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cerivastatin + Methoxsalen DCKS8GD Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Chlorzoxazone + Methoxsalen DCVROL3 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Docetaxel + Methoxsalen DCR2R75 Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Emetine + Methoxsalen DCRSLDO Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Epinephrine + Methoxsalen DC6Q8BN Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Imipramine + Methoxsalen DC5F6AG Imipramine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
IT-141 + Methoxsalen DCAHQK4 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Itraconazole + Methoxsalen DCPH593 Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Methoxsalen DC6JP7D Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metaxalone + Methoxsalen DCXIJTG Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Ribavirin-TP DCPIIZT Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Acetazolamide DCM7G4L Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Tacrine DCC9Y18 Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Vinblastine DCLXI0L Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Mephenytoin DCIQJYD Mephenytoin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Triapine DC7W9QG Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Pepstatin DC81QI7 Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + BHV-0223 DCNGDNI BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Isoproterenol DCRSHYA Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Tiagabine DCMLIP7 Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Benserazide DCRVEO9 Benserazide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Mebendazole DCCG7IG Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Trimethobenzamide DCNJQ99 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Maprotiline DCHYSRJ Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Oxyphenbutazone DC7QKGG Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Mycophenolic acid DCPDQKM Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Hydralazine DCNOOTI Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Oxandrolone DCTVVXU Oxandrolone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Mefloquine DC1JUMW Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Lacosamide DC2IIDC Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Nabilone DCV5UPN Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Cerivastatin DCOHZ11 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Moricizine + Methoxsalen DCAD48U Moricizine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Methoxsalen DCI2CXY Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Oseltamivir + Methoxsalen DCWR7NQ Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pramipexole + Methoxsalen DCTIAZN Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Probenecid + Methoxsalen DCMSN2P Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pyrazinamide + Methoxsalen DC5UU8V Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Sulfinpyrazone + Methoxsalen DC2UZRR Sulfinpyrazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trimethobenzamide + Methoxsalen DCOSKXV Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vorinostat + Methoxsalen DCXSFRH Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Zileuton + Methoxsalen DCDP39F Zileuton Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 47 DrugCom(s)
2 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Cyclophosphamide + Methoxsalen DC877LM Cyclophosphamide Leukemia [4]
Methoxsalen + Bexarotene DCGKP0J Bexarotene Lymphoma [5]
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References

1 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 009048.
2 Methoxsalen FDA Label
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 ClinicalTrials.gov (NCT00005092) Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
5 ClinicalTrials.gov (NCT00056056) Ultraviolet Light Therapy Using Methoxsalen With or Without Bexarotene in Treating Patients With Mycosis Fungoides