Details of the Drug Combinations

General Information of This Drug (ID: DMFA5MY)

• Drug Name: Metoclopramide (DMFA5MY)
• Synonyms: Cerucal; Clopra; Clopromate; Duraclamid; Elieten; Emetid; Emitasol; Emperal; Eucil; Gastrese; Gastrobid; Gastromax; Gastronerton; Gastrosil; Gastrotablinen; Gastrotem; Imperan; Maxeran; Maxolon; Meclopran; Metaclopramide; Metaclopromide; Metamide; Methochlopramide; Methoclopramide; Metochlopramide; Metoclol; Metoclopramida; Metoclopramidum; Metocobil; Metramid; Moriperan; Mygdalon; Octamide; Parmid; Paspertin; Peraprin; Plasil; Pramidin; Pramiel; Pramin; Primperan; Reclomide; Reglan; Reliveran; Terperan; Metoclopramide Omega; DEL 1267; Apo-Metoclop; CLOPRA-YELLOW; Clopra-Yellow; Degan (TN); Elieten (TN); Gastro-Timelets; Maxeran (TN); Maxolon (TN); Metoclopramida [INN-Spanish]; Metoclopramide Monohydrochloride, Monohydrate; Metoclopramidum [INN-Latin]; Neu-Sensamide; Nu-Metoclopramide; Plasil (pharmaceutical); Pms-Metoclopramide; Primperan (TN); Pylomid (TN); Reglan (TN); Terperan (TN); Metoclopramide (JP15/INN); Metoclopramide [INN:BAN:JAN]; N-(Diethylaminoethyl)-2-methoxy-4-amino-5-chlorobenzamide; O-Anisamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-(8CI); Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy-(9CI); (metaclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide; (metoclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide; 1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one; 2-Methoxy-4-amino-5-chloro-N,N-dimethylaminoethyl)benzamide; 2-Methoxy-5-chloroprocainamide; 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide; 4 Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide; 4-Amino-5-chloro-2-methoxy-N-(beta-diethylaminoethyl)benzamide; 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide; 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide; 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide; 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (Mcp); 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (metoclopramide); 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide(Metoclopramide); 4-amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxybenzamide; 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide; 5-Chloro-2-methoxyprocainamide

Indication

Nausea; ICD 11: MD90; Status: Approved [1]

• Therapeutic Class: Antiemetics
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

12 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Dexamethasone + Metoclopramide	DC6VM8I	Dexamethasone	Nausea and Vomiting	[2]
Metoclopramide + Propofol	DC6B6SG	Propofol	PREGNANCY	[3]
Metoclopramide + Ketoprofen	DC9YN1O	Ketoprofen	Migraine	[4]
Metoclopramide + Diphenhydramine	DCEHPCA	Diphenhydramine	Migraine	[5]
Metoclopramide + Diphenhydramine	DCGBR5R	Diphenhydramine	Nausea	[6]
Metoclopramide + Ketorolac	DCZB71G	Ketorolac	Probable Migraine	[7]
Dexamethasone + Metoclopramide	DCH1LU6	Dexamethasone	Malignant Bowel Obstruction	[8]
Metoclopramide + Tramadol	DCYEKD5	Tramadol	Trauma	[9]
Dexamethasone + Metoclopramide	DC83ODJ	Dexamethasone	Headache	[10]
Metoclopramide + Ondansetron	DC91J70	Ondansetron	Postoperative Pain	[11]
Metoclopramide + Ondansetron	DC531GA	Ondansetron	Nausea	[12]
Metoclopramide + Methylprednisolone	DCCETDO	Methylprednisolone	Migraine	[13]

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 241).
• [2] ClinicalTrials.gov (NCT00003213) Drugs to Reduce the Side Effects of Chemotherapy
• [3] ClinicalTrials.gov (NCT01781377) Prophylactic Subhypnotic Propofol for Nausea and Vomiting During for Cesarean Section Under Subarachnoid Anesthesia.
• [4] ClinicalTrials.gov (NCT00557544) Trial on Metoclopramide and Ketoprofen in Acute Migraine of Childhood
• [5] ClinicalTrials.gov (NCT00682734) Metoclopramide for Migraine: A Dose Finding Study
• [6] ClinicalTrials.gov (NCT00475306) The Montefiore Metoclopramide Study
• [7] ClinicalTrials.gov (NCT01596166) Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department
• [8] ClinicalTrials.gov (NCT04027348) Palliative Management of Inoperable Malignant Bowel Obstruction
• [9] ClinicalTrials.gov (NCT03383315) Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients
• [10] ClinicalTrials.gov (NCT03081416) "THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"
• [11] ClinicalTrials.gov (NCT01837394) Ultrasound-guided Blocks for Ambulatory Knee Arthroscopy
• [12] ClinicalTrials.gov (NCT02959840) Acupuncture Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean
• [13] ClinicalTrials.gov (NCT02847494) Corticosteroids for Acute Migraine in the Emergency Department