Details of the Drug Combinations

General Information of This Drug (ID: DMGB035)

Drug Name

Armodafinil DMGB035

Synonyms

Nuvigil; 112111-43-0; (R)-Modafinil; (R)-(-)-Modafinil; CEP-10953; UNII-V63XWA605I; CRL 40982; CEP 10953; V63XWA605I; CHEMBL1201192; CHEBI:77590; 2-[(R)-(Diphenylmethyl)sulfinyl]acetamide; (-)-2-((R)-(Diphenylmethyl)sulfinyl)acetamide; (-)-2-[(r)-(diphenylmethyl)sulfinyl]acetamide; Armodafinil [USAN:INN]; armodafinilo; armodafinilum; l-Modafinil; Nuvigil (TN); (-)-(R)-modafinil; Armodafinil (USAN/INN); SCHEMBL34489; ZINC6156; ACE037; Armodafinil, > YFGHCGITMMYXAQ-LJQANCHMSA-N

Indication

Disease Entry	ICD 11	Status	REF
Malignant glioma	2A00.0	Approved	[1]
Methamphetamine dependence	6C46.2	Approved	[1]
Narcolepsy	7A20	Approved	[1]
Pain	MG30-MG3Z	Approved	[1]
Pediatric cancer	2A00-2F9Z	Approved	[2]
Postpoliomyelitis syndrome	N.A.	Approved	[1]
Traumatic brain injury	NA07.Z	Approved	[1]
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⏷ Show the Full List of Indication(s)

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

94 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Abacavir + Armodafinil	DCDH2UO	Abacavir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Acamprosate + Armodafinil	DCIBHOA	Acamprosate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Gefitinib	DC8RSXN	Gefitinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Paromomycin	DCSTYGR	Paromomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Dantrolene	DCCTYY6	Dantrolene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Dactinomycin	DC5IY6O	Dactinomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Terazosin	DC9GR0I	Terazosin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + PMID28460551-Compound-2	DC2D8K2	PMID28460551-Compound-2	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Vinblastine	DCE01KH	Vinblastine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Mephenytoin	DCMKAGT	Mephenytoin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Anamorelin	DCG3T1X	Anamorelin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Triapine	DCIULMF	Triapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Pepstatin	DCDNT5O	Pepstatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + IT-141	DCRDWZK	IT-141	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Metyrosine	DC5JZFI	Metyrosine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Terameprocol	DCD5XBM	Terameprocol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + SCH 727965	DC4SLL5	SCH 727965	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Docetaxel	DCGZ59U	Docetaxel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Ginsenoside Rb1	DCD1SGW	Ginsenoside Rb1	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Ciprofibrate	DCNKBEN	Ciprofibrate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Clopidogrel	DC9T8PF	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Tolazoline	DC3Q4LG	Tolazoline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Procarbazine	DCBMRGX	Procarbazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + BIO-300	DCXJJHM	BIO-300	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Niclosamide	DCEUZJ3	Niclosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Isoproterenol	DC7H6EH	Isoproterenol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + GINKGOLIDE A	DCMVRRN	GINKGOLIDE A	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Diazoxide	DCKDTM5	Diazoxide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Tamoxifen	DCJLAHP	Tamoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Imatinib	DCKKGBE	Imatinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Probenecid	DCP3LDK	Probenecid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Pramipexole	DCUP5O0	Pramipexole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Methylene blue	DCTS6S7	Methylene blue	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Dopamine	DCEVXCK	Dopamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Maprotiline	DCMUNP3	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Brincidofovir	DCSQTME	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Amantadine	DCHFH3R	Amantadine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Mycophenolic acid	DCXL9M2	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Oxandrolone	DCJHJDN	Oxandrolone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Mefloquine	DCDAXT3	Mefloquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Pizotyline	DC6FHKI	Pizotyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Lacosamide	DC9B1PP	Lacosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Doxorubicin	DC2KU6U	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Nabilone	DCGXTY3	Nabilone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Testolactone	DCWS59A	Testolactone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Vorinostat	DCCP74R	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Enoxacin	DCRRUSV	Enoxacin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Raltegravir	DC2DPIR	Raltegravir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + AS-1949490	DCJ5ES6	AS-1949490	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Cytarabine	DCTJQOC	Cytarabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Artemisinin + Armodafinil	DCH4ZCI	Artemisinin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Auranofin + Armodafinil	DCC6TUG	Auranofin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Azatadine + Armodafinil	DCS3BIK	Azatadine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
BHV-0223 + Armodafinil	DCM7F78	BHV-0223	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
BIO-300 + Armodafinil	DCN88A1	BIO-300	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Brincidofovir + Armodafinil	DCLB7HK	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Carglumic acid + Armodafinil	DCDXIZS	Carglumic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Chlorzoxazone + Armodafinil	DC6I6D8	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Clindamycin + Armodafinil	DCDAJHU	Clindamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Crotamiton + Armodafinil	DCFWYJD	Crotamiton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cytarabine + Armodafinil	DCHS3J8	Cytarabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dexmedetomidine + Armodafinil	DCR3XDU	Dexmedetomidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Diethylcarbamazine + Armodafinil	DC0ZWXV	Diethylcarbamazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Doxorubicin + Armodafinil	DCBWV85	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
ETHISTERONE + Armodafinil	DCA6CNB	ETHISTERONE	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fluspirilene + Armodafinil	DC9Z82C	Fluspirilene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fomepizole + Armodafinil	DC8EQBI	Fomepizole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
GINKGOLIDE A + Armodafinil	DC6EK73	GINKGOLIDE A	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
GSK2194069 + Armodafinil	DCTRLUN	GSK2194069	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Idarubicin + Armodafinil	DCIOXQ9	Idarubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
IT-141 + Armodafinil	DCCJE9A	IT-141	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
L-165041 + Armodafinil	DC7BT4F	L-165041	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Lacosamide + Armodafinil	DCCCFPJ	Lacosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Levamisole + Armodafinil	DC78U1R	Levamisole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mefloquine + Armodafinil	DCUY7F5	Mefloquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Memantine + Armodafinil	DCZWFT6	Memantine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Metaxalone + Armodafinil	DCY4IHP	Metaxalone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mycophenolic acid + Armodafinil	DCE0C2L	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Nitrosoglutathione + Armodafinil	DCCA15P	Nitrosoglutathione	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Oxyphenbutazone + Armodafinil	DC2HGR2	Oxyphenbutazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PF-02545920 + Armodafinil	DCS5WS4	PF-02545920	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pinacidil + Armodafinil	DC7W7NR	Pinacidil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pyrazinamide + Armodafinil	DCCXNP9	Pyrazinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Quinine + Armodafinil	DC1CCYV	Quinine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Sumatriptan + Armodafinil	DCQEPDX	Sumatriptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tamoxifen + Armodafinil	DCXOAXR	Tamoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Testolactone + Armodafinil	DCE8QMH	Testolactone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tiagabine + Armodafinil	DCCFU51	Tiagabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tolazoline + Armodafinil	DC6BACE	Tolazoline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trihexyphenidyl + Armodafinil	DCO3YC3	Trihexyphenidyl	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Triiodothyronine + Armodafinil	DC1NSOL	Triiodothyronine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ursodeoxycholic acid + Armodafinil	DCKCGT1	Ursodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Vorinostat + Armodafinil	DCTM9KD	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Zaleplon + Armodafinil	DC8Y4Y8	Zaleplon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
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⏷ Show the Full List of 94 DrugCom(s)

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Armodafinil + Curcumin	DCLOZU5	Curcumin	Non Small Cell Lung Cancer	[4]
Bupropion + Armodafinil	DCS8X9W	Bupropion	Non Small Cell Lung Cancer	[4]
Bupropion + Armodafinil	DCGCVBI	Bupropion	Non Small Cell Lung Cancer	[4]
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References

1	Armodafinil FDA Label
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4	ClinicalTrials.gov (NCT01048983) Reducing Symptom Burden - Non Small Cell Lung Cancer (NSCLC)