Details of the Drug Combinations

General Information of This Drug (ID: DMGV8QU)

Drug Name

Etravirine DMGV8QU

Synonyms

Intelence; DAPY deriv; Diaminopyrimidine deriv; R 165335; R165335; TMC 125; TMC125; Intelence (TN); Intelence(TM); R-165335; R165335-TMC125; TMC-125; Etravirine (JAN/USAN/INN); TMC-125/R-165335; 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-benzonitrile; 4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE; 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile; 65B; ETR

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus-1 infection	1C62	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

6 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Etravirine + Maraviroc	DC70SA6	Maraviroc	HIV Infections	[2]
Etravirine + Darunavir	DC7ZBPE	Darunavir	HIV Infections	[2]
Etravirine + Darunavir	DCV1JJ5	Darunavir	HIV-1 Infection	[3]
Etravirine + Darunavir	DCPI6UX	Darunavir	HIV/AIDS	[4]
Etravirine + Darunavir	DC5AHVN	Darunavir	Human Immunodeficiency Virus (HIV)	[5]
Etravirine + Darunavir	DC8931X	Darunavir	Acute HIV Infection	[6]
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⏷ Show the Full List of 6 DrugCom(s)

References

1	Emerging antiviral drugs. Expert Opin Emerg Drugs. 2008 Sep;13(3):393-416.
2	ClinicalTrials.gov (NCT00977756) IMPAACT P1058A: Pharmacokinetic Effects of New Antiretroviral Drugs on Children, Adolescents and Young Adults
3	ClinicalTrials.gov (NCT01641367) A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure
4	ClinicalTrials.gov (NCT00855088) Study in Healthy Males to Measure Darunavir and Etravirine in Blood, Seminal Fluid, and Rectal Tissue
5	ClinicalTrials.gov (NCT01199939) A Study of the Once Daily Combination of Etravirine and Darunavir/Ritonavir As Dual Therapy in Early Treatment-Experienced Patients
6	ClinicalTrials.gov (NCT00855413) HIV Viremia and Persistence in Acutely HIV-Infected Patients Treated With Darunavir/Ritonavir and Etravirine