Details of the Drug Combinations

General Information of This Drug (ID: DMHWE7P)

Drug Name
Ampicillin   DMHWE7P
Synonyms
ABPC; Acillin; Adobacillin; Alpen; Amblosin; Amcill; Amfipen; Aminobenzylpenicillin; Ampen; Ampichel; Ampicil; Ampicilina; Ampicillanyl; Ampicillina; Ampicilline; Ampicillinum; Ampicin; Ampifarm; Ampikel; Ampimed; Ampipenin; Ampiscel; Ampisyn; Ampivax; Ampivet; Amplacilina; Amplin; Amplipenyl; Amplisom; Amplital; Austrapen; Binotal; Bonapicillin; Britacil; Campicillin; Cimex; Copharcilin; Delcillin; Deripen; Divercillin; Doktacillin; Duphacillin; Grampenil; Guicitrina; Guicitrine; Lifeampil; Morepen; Norobrittin; Nuvapen; Omnipen; Orbicilina; Penbristol; Penbritin; Penbrock; Penicline; Penimic; Pensyn; Pentrex; Pentrexl; Pentrexyl; Polycillin; Ponecil; Princillin; Principen; QIDamp; Racenacillin; Rosampline;Roscillin; Semicillin; Servicillin; Sumipanto; Supen; Synpenin; Texcillin; Tokiocillin; Tolomol; Totacillin; Totalciclina; Totapen; Trifacilina; Ukapen; Ultrabion; Ultrabron; Vampen; Viccillin; Wypicil; Amfipen V; Amipenix S; Ampicillin A; Ampicillin Anhydrous; Ampicillin Base; Ampicillin acid; Ampicillin anhydrate; Ampicillina [DCIT]; Anhydrous ampicillin; Olin Kid; Pen A; Pen A Oral; Pen Ampil;Penbritin paediatric; Penbritin syrup; Pfizerpen A; Semicillin R; Viccillin S; AY 6108; BA 7305; BRL 1341; Bayer 5427; HI 63; P 50; Principen 125; Principen 250; Principen 500; SQ 17382; AB-PC; AB-PCSol; AY-6108; Ambidrin (TN); Ampi-Co; Ampi-Tab; Ampi-bol; Ampicilina [INN-Spanish]; Ampicilline [INN-French]; Ampicillinum [INN-Latin]; Ampipenin, nt3; Ampy-Penyl; Anhydrous ampicillin (JP15); BRL-1341; D-Ampicillin; D-Cillin; KS-R1; Novo-ampicillin; OMNIPEN (AMPICILLIN); Omnipen (TN); Omnipen-N; P-50; Penbritin-S; Penicillin, Aminobenzyl; Pfizerpen-A; Polycillin-N; Polyflex (Veterinary); Ro-Ampen; SK-Ampicillin; Totacillin (sodium); Totacillin-N; WY-5103; Ampicillin (USP/INN); AMPICILLIN (SEE ALSO AMPICILLIN TRIHYDRATE 7177-48-2); Ampicillin [USAN:BAN:INN:JAN]; Ampicillin [USAN:INN:BAN:JAN];D-(-)-Ampicillin; D-(-)-alpha-Aminobenzylpenicillin; D-(-)-alpha-Aminopenicillin; D-(-)-6-(alpha-Aminophenylacetamido)penicillanic acid; 6-(D(-)-alpha-Aminophenylacetamido)penicillanic acid; 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carbonyl; 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylic acid
Indication
Disease Entry ICD 11 Status REF
Acute epiglottitis N.A. Approved [1]
Acute gonococcal cervicitis N.A. Approved [1]
Acute otitis media AB00 Approved [1]
Bacillary dysentery 1A02 Approved [1]
Bacteremia 1A73 Approved [1]
Bacterial endocarditis N.A. Approved [1]
Bacterial infection 1A00-1C4Z Approved [2]
Cholangitis N.A. Approved [1]
Chorioamnionitis N.A. Approved [1]
Dysentery N.A. Approved [1]
Escherichia coli meningitis N.A. Approved [1]
Meningococcal meningitis N.A. Approved [1]
Peritonitis N.A. Approved [1]
Pneumococcal meningitis N.A. Approved [1]
Staphylococcal pneumonia N.A. Approved [1]
Staphylococcus aureus infection N.A. Approved [1]
Streptococcal pneumonia N.A. Approved [1]
Urinary tract infection GC08 Approved [1]
Paratyphoid fever N.A. Investigative [1]
Pelvic inflammatory disease GA05 Investigative [1]
Sinusitis CA0A.Z Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Ampicillin + Nalidixic acid DC5RJDR Nalidixic acid Typhoid fever (Cell Line: .) [3]
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9 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Ampicillin + Azithromycin DCOTKBU Azithromycin Preterm Pre-labor Rupture of Membranes [4]
Ampicillin + Gentamicin DCHJI8J Gentamicin Nephrolithiasis [5]
Ampicillin + Gentamicin DC7CAAS Gentamicin Premature Birth of Newborn [6]
Ampicillin + Azithromycin DCTXX6Y Azithromycin Preterm Pre-labor Rupture of Membranes [4]
Dexamethasone + Ampicillin DCI7DR4 Dexamethasone Preterm Premature Rupture of Membrane [7]
Nitrofurantoin + Ampicillin DCKTBEW Nitrofurantoin Nephrolithiasis [5]
Ampicillin + Azithromycin DC79T9J Azithromycin Preterm Premature Rupture of Membranes (PPROM) [8]
Ampicillin + Gentamicin DCK8MBI Gentamicin Premature Birth [9]
Erythromycin + Ampicillin DCKDD7Y Erythromycin Preterm Premature Rupture of Membranes (PPROM) [8]
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⏷ Show the Full List of 9 DrugCom(s)

References

1 Ampicillin FDA Label
2 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 061936.
3 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
4 ClinicalTrials.gov (NCT04202380) Azithromycin for Preterm Pre-labor Rupture of Membranes
5 ClinicalTrials.gov (NCT02829060) Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
6 ClinicalTrials.gov (NCT02477423) A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome
7 ClinicalTrials.gov (NCT03473210) The Value of Amniopatch in Preterm Premature Rupture of Membranes
8 ClinicalTrials.gov (NCT03060473) Treatment of ppROM With Erythromycin vs. Azithromycin Trial
9 ClinicalTrials.gov (NCT05977400) NICU Antibiotics and Outcomes (NANO) Follow-up Study