Details of the Drug Combinations

General Information of This Drug (ID: DMI7DZ2)

Drug Name

Prilocaine DMI7DZ2

Synonyms

Citanest; Prilocaina; Prilocainum; Propitocaine; Prilocaine [USAN]; Prilocaine base; Astra 1512; Astra 1515; L 67; Citanest (TN); Prilocaina [INN-Spanish]; Prilocainum [INN-Latin]; Propitocaine (JAN); Prilocaine (USP/INN); O-Methyl-2-propylaminopropionanilide; O-Methyl-alpha-propylaminopropionanilide; Alpha-n-Propylamino-2-methylpropionanilide; N-[2-Methylphenyl]-2-[propylamino]propanamide; N-(2-methylphenyl)-N2-propylalaninamide; N-(2-Methylphenyl)-2-(propylamino)propanamide; N-(2-methylphenyl)-N(2)-propylalaninamide; Propanamide, N-(2-methylphenyl)-2-(propylamino)-(9CI); 2-(Propylamino)-o-propionotoluidide; 2-Methyl-.alpha.-propylaminopropionanilide; 2-Methyl-alpha-propylaminopropionanilide

Indication

Disease Entry	ICD 11	Status	REF
Pain	MG30-MG3Z	Approved	[1]
Premature ejaculation	HA03.0Z	Investigative	[2]
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Therapeutic Class

Anesthetics

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

4 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Prilocaine + Prilocaine	DCCT9AW	Prilocaine	Other Surgical Procedures	[3]
Prilocaine + Midazolam	DCJE108	Midazolam	Other Surgical Procedures	[4]
Prilocaine + Morphine	DCWCX0J	Morphine	Pregnant Women	[5]
Felypressin + Prilocaine	DCNA2UX	Felypressin	Overcoming the Failure of Anaesthesia	[6]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7276).
2	Prilocaine FDA Label
3	ClinicalTrials.gov (NCT01643616) Ultrasound Guided Distal Sciatic Nerve Block - a Comparison With Nerve Stimulator Technique
4	ClinicalTrials.gov (NCT01309360) Ultrasound-guided Axillary Plexus Block - Dose Reduction of Prilocaine
5	ClinicalTrials.gov (NCT03607916) Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.
6	ClinicalTrials.gov (NCT04236115) Comparison of Articaine and Prilocaine for Extraction of Maxillary Teeth