Details of the Drug Combinations

General Information of This Drug (ID: DMIZ6W2)

• Drug Name: Norfloxacin (DMIZ6W2)
• Synonyms: Baccidal; Barazan; Chibroxin; Fulgram; Lexinor; NFLX; Norflo; Norfloxacine; Norfloxacino; Norfloxacinum; Noroxin; Sebercim; Merck Brand of Norfloxacin; Norfloxacin Merck Brand; AM 0715; AM 715; AM0715; MK 0366; MK 366; MK0366; MK366; AM-0715; AM-715; Chibroxin (TN); Insensye (TN); MK-0366; MK-366; Norflohexal (TN); Norfloxacine [INN-French]; Norfloxacino [INN-Spanish]; Norfloxacinum [INN-Latin]; Norfocin (TN); Noroxin (TN); Nufloxib (TN); Roxin (TN); Utin (TN); Utinor (TN); Apo-Norflox (TN); Norfloxacin (JP15/USP/INN); Norfloxacin [USAN:BAN:INN:JAN]; Chibroxin, MK-366, Baccidal, Sebercim, Zoroxin, Norfloxacin; 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[1-piperazinyl]-3-quinoline-carboxylic acid; 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid; 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid; 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

Indication

Acute gonococcal cervicitis; ICD 11: N.A.; Status: Approved [1]; Acute maxillary sinusitis; ICD 11: N.A.; Status: Approved [1]; Anthrax; ICD 11: 1B97; Status: Approved [1]; Bacillary dysentery; ICD 11: 1A02; Status: Approved [1]; Bacterial infection; ICD 11: 1A00-1C4Z; Status: Approved [2]; Bronchitis; ICD 11: CA20; Status: Approved [1]; Chancroid; ICD 11: N.A.; Status: Approved [1]; Chronic tubotympanic suppurative otitis media; ICD 11: N.A.; Status: Approved [1]; Cystitis; ICD 11: GC00; Status: Approved [1]; Endomyometritis; ICD 11: N.A.; Status: Approved [1]; Malignant otitis externa caused by Pseudomonas aeruginosa; ICD 11: N.A.; Status: Approved [1]; Mycoplasma pneumoniae pneumonia; ICD 11: N.A.; Status: Approved [1]; Peritonitis; ICD 11: N.A.; Status: Approved [1]; Pneumonia; ICD 11: CA40; Status: Approved [1]; Prostatitis; ICD 11: N.A.; Status: Approved [1]; Pyelonephritis; ICD 11: N.A.; Status: Approved [1]; Staphylococcal pneumonia; ICD 11: N.A.; Status: Approved [1]; Staphylococcus aureus infection; ICD 11: N.A.; Status: Approved [1]; Streptococcal pneumonia; ICD 11: N.A.; Status: Approved [1]; Traveler's diarrhea; ICD 11: ME05.1; Status: Approved [1]; Urinary tract infection; ICD 11: GC08; Status: Approved [1]; Pneumonia caused by chlamydia; ICD 11: N.A.; Status: Investigative [1]; Pneumonia due to Klebsiella pneumoniae; ICD 11: CA40.03; Status: Investigative [1]

• Therapeutic Class: Antibiotics
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Itopride + Norfloxacin	DCYGOD5	Itopride	Spontaneous Bacterial Peritonitis	[3]
Nitazoxanide + Norfloxacin	DCLBY5P	Nitazoxanide	Spontaneous Bacterial Peritonitis	[4]

References

• [1] Norfloxacin FDA Label
• [2] FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074690.
• [3] ClinicalTrials.gov (NCT04161768) Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis
• [4] ClinicalTrials.gov (NCT04746937) Nitazoxanide in Prevention of Secondary Spontaneous Peritonitis