Details of the Drug Combinations

General Information of This Drug (ID: DMJH792)

• Drug Name: Pitavastatin (DMJH792)
• Synonyms: Pitavastatin; Itavastatin; Livalo; NK 104; Pitavastatin [INN]; Pitavastatin calcium; UNII-M5681Q5F9P; NK-104; C25H24FNO4; M5681Q5F9P; Zypitamag; Flovas; (3R,5S,6E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid; P 872441; P-872441; (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid; ( )-(3R,5S,6E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoic acid; NK 104 (acid); Pitavastatin calcium (JAN)

Indication

Hypercholesterolaemia; ICD 11: 5C80.0; Status: Approved [1]; Hyperlipidemia, familial combined, LPL related; ICD 11: N.A.; Status: Approved [1]

List of Combinatorial Drugs (CBD) Containing This Drug

6 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Atorvastatin + Pitavastatin	DCG1B0D	Atorvastatin	Hypercholesterolemia	[2]
Efavirenz + Pitavastatin	DCD1FIL	Efavirenz	Hyperlipidemia	[3]
Ezetimibe + Pitavastatin	DCPE8J5	Ezetimibe	Hypercholesterolemia	[4]
Pitavastatin + Darunavir	DCJ3HP0	Darunavir	Hyperlipidemia	[3]
Pitavastatin + Rosuvastatin	DCATKSL	Rosuvastatin	Hypercholesterolemia	[2]
Venetoclax + Pitavastatin	DC63ETM	Venetoclax	Acute Myeloid Leukemia	[5]

References

• [1] Pitavastatin FDA Label
• [2] ClinicalTrials.gov (NCT01660191) A Study Comparing CoQ10 Levels While Taking 3 Different Statins. U.S. National Institutes of Health.
• [3] ClinicalTrials.gov (NCT01695954) Pharmacokinetic Study of Pitavastatin and Ritonavir-Boosted Darunavir or Efavirenz
• [4] ClinicalTrials.gov (NCT00653913) Evaluation of Potential for Drug Interaction Between SCH 58235 (Ezetimibe) and Pitavastatin (Study P03962)(COMPLETED)
• [5] ClinicalTrials.gov (NCT04512105) Pitavastatin in Combination With Venetoclax for Chronic Lymphocytic Leukemia or Acute Myeloid Leukemia