Details of the Drug Combinations

General Information of This Drug (ID: DMKBYWI)

Drug Name

Trifluoperazine DMKBYWI

Synonyms

Calmazine; Eskazine; Fluoperazine; Flurazine; Modalina; Stelazine; Stellazine; TFP; Trifluoperazin; Trifluoperazina; Trifluoperazinum; Trifluoromethylperazine; Trifluoroperazine; Trifluperazine; Triflurin; Trifluroperizine; Triftazin; Triftazine; Triperazine; Triphtazin; Triphtazine; Triphthasine; PMS Trifluoperazine; Stelazine Concentrate; Trifluoperazina [Italian]; Trifluoperazine HCl; Trifluoperazine dihydrochloride; Trifluoroperazine dihydrochloride; Tripfluoperazine Hydrochloride; NCI17474; RP 7623; SKF 5019; Apo-Trifluoperazine; Eskazine (TN); Eskazinyl (TN); Jatroneural (TN); Modalina (TN); Novo-Trifluzine; Stelazine (TN); Terfluzine (TN); Trifluoperaz (TN); Trifluoperazina [INN-Spanish]; Trifluoperazine (INN); Trifluoperazine [INN:BAN]; Trifluoperazinum [INN-Latin]; Apo-trifluoperazine (TN); Stelazine (*Dihydrochloride*); Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine; 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)phenothiazine; 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazine; 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-phenothiazine; 10-(gamma-(N'-Methylpiperazino)propyl)-2-trifluoromethylphenothiazine; 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE; 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine; 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine; 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine; 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine dihydrochloride; 2-Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine

Indication

Disease Entry	ICD 11	Status	REF
Anxiety	N.A.	Approved	[1]
Schizophrenia	6A20	Approved	[2]
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Therapeutic Class

Antipsychotic Agents

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

65 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Acarbose + Trifluoperazine	DC3EUDO	Acarbose	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Arfolitixorin + Trifluoperazine	DCGKAS5	Arfolitixorin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Artemisinin + Trifluoperazine	DCFO40C	Artemisinin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Artemisinin + Trifluoperazine	DCOWHZY	Artemisinin	DD2 (Cell Line: DD2)	[3]
Bortezomib + Trifluoperazine	DCNC9RM	Bortezomib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Brincidofovir + Trifluoperazine	DCHVD8U	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Chloroquine + Trifluoperazine	DCEYF9P	Chloroquine	DD2 (Cell Line: DD2)	[3]
Clopidogrel + Trifluoperazine	DCV5YDW	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Crotamiton + Trifluoperazine	DCSEEEH	Crotamiton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dantrolene + Trifluoperazine	DC8DP88	Dantrolene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Darunavir + Trifluoperazine	DCXTKF0	Darunavir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Diazoxide + Trifluoperazine	DCWUPW1	Diazoxide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dichlorphenamide + Trifluoperazine	DCWFLEV	Dichlorphenamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Diethylcarbamazine + Trifluoperazine	DCIEGS1	Diethylcarbamazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Docetaxel + Trifluoperazine	DC3XUGS	Docetaxel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Entacapone + Trifluoperazine	DC1I6NV	Entacapone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fenoprofen + Trifluoperazine	DCZL6CR	Fenoprofen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fluspirilene + Trifluoperazine	DCA0JR6	Fluspirilene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fomepizole + Trifluoperazine	DCBQQCI	Fomepizole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Gefitinib + Trifluoperazine	DCW76ZK	Gefitinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
GS4071 + Trifluoperazine	DCJTJOR	GS4071	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Hyodeoxycholic acid + Trifluoperazine	DCMH0Q8	Hyodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Imatinib + Trifluoperazine	DCQRZVJ	Imatinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Isoproterenol + Trifluoperazine	DC56ANW	Isoproterenol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
JZL195 + Trifluoperazine	DC6B9I6	JZL195	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
L-165041 + Trifluoperazine	DCQSXYI	L-165041	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Lacosamide + Trifluoperazine	DCV56LR	Lacosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
LY03004 + Trifluoperazine	DCC86CB	LY03004	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Metyrosine + Trifluoperazine	DC9RWMI	Metyrosine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Nabilone + Trifluoperazine	DCNU93E	Nabilone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pentamidine + Trifluoperazine	DC8SMFS	Pentamidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pepstatin + Trifluoperazine	DC7AQVT	Pepstatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pinacidil + Trifluoperazine	DCUYAAW	Pinacidil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PMID28460551-Compound-2 + Trifluoperazine	DCQXNU0	PMID28460551-Compound-2	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pyrazinamide + Trifluoperazine	DCL6407	Pyrazinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Repaglinide + Trifluoperazine	DC1PBKF	Repaglinide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Terameprocol + Trifluoperazine	DC33OSM	Terameprocol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Testosterone cypionate + Trifluoperazine	DCLS69Y	Testosterone cypionate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Sertraline	DCQT3VK	Sertraline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Citalopram	DCKACTS	Citalopram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Panobinostat	DCPFGOZ	Panobinostat	Diffuse intrinsic pontine glioma (Cell Line: DIPG25)	[3]
Trifluoperazine + IT-141	DC9T13A	IT-141	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Efavirenz	DC7WL3L	Efavirenz	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + SCH 727965	DCITX4X	SCH 727965	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Itraconazole	DCRQ5W8	Itraconazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Emetine	DCUCWV3	Emetine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Chlorzoxazone	DCBQE0Z	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Sulfinpyrazone	DCASK4E	Sulfinpyrazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Fibrates	DCUY29R	Fibrates	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Tiagabine	DCLTRAS	Tiagabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Methylene blue	DCD45QD	Methylene blue	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Maprotiline	DCWNO7Z	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Oxyphenbutazone	DCXDBCH	Oxyphenbutazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Leflunomide	DCLFR9R	Leflunomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Brincidofovir	DCGOGTW	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Cisatracurium	DCM3LOX	Cisatracurium	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Mefloquine	DCBV1HA	Mefloquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Doxorubicin	DCLVC6H	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Auranofin	DCO2I3K	Auranofin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Vorinostat	DCT4SO1	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Cerivastatin	DC0PYJL	Cerivastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trifluoperazine + Tetracycline	DCAWMT1	Tetracycline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trihexyphenidyl + Trifluoperazine	DCQP8D5	Trihexyphenidyl	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Triiodothyronine + Trifluoperazine	DCYCRPP	Triiodothyronine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Vinblastine + Trifluoperazine	DCVNR53	Vinblastine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
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⏷ Show the Full List of 65 DrugCom(s)

References

1	Trifluoperazine FDA Label
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.