Details of the Drug Combinations

General Information of This Drug (ID: DMKFQJP)

Drug Name
Triflupromazine   DMKFQJP
Synonyms
Adazine; Fluopromazine; Fluorofen; Neoprin; Nivoman; Psyquil; Siquil; Trifluopromazine; Triflupromazina; Triflupromazinum;Vesprin; Vetame; Fluopromazine monohydrochloride; Trifluopromazine hydrochloride; Triflupromazine [INN]; Triflupromazina [INN-Spanish]; Triflupromazinum [INN-Latin]; Vesprin (TN); Triflupromazine (USP/INN)
Indication
Disease Entry ICD 11 Status REF
Nausea MD90 Approved [1]
Psychotic disorder 6A20-6A25 Approved [2]
Vomiting MD90 Approved [1]
Schizophrenia 6A20 Withdrawn from market [3]
Middle East Respiratory Syndrome (MERS) 1D64 Investigative [4]
Severe acute respiratory syndrome (SARS) 1D65 Investigative [4]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antipsychotic Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

96 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Abacavir + Triflupromazine DC22MR0 Abacavir Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Acamprosate + Triflupromazine DCWFS3C Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Acetohexamide + Triflupromazine DCXF85G Acetohexamide Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Aciclovir + Triflupromazine DC35DLQ Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Arfolitixorin + Triflupromazine DCT3Z69 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Artemisinin + Triflupromazine DCE8SJE Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Bepridil + Triflupromazine DC7NOK4 Bepridil Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Brincidofovir + Triflupromazine DCFZJ24 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Cerivastatin + Triflupromazine DC8P5J2 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Chlorzoxazone + Triflupromazine DCHIUKS Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Cilostazol + Triflupromazine DCOM1NW Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Ciprofibrate + Triflupromazine DCID53B Ciprofibrate Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Clascoterone + Triflupromazine DC6FWHO Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Diazoxide + Triflupromazine DCT74NS Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Diphenidol + Triflupromazine DC6QWGU Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Docetaxel + Triflupromazine DCE717Y Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Dronedarone + Triflupromazine DCXB723 Dronedarone Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Endoxifen + Triflupromazine DC26RX8 Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Epinephrine + Triflupromazine DC2RO7L Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Everolimus + Triflupromazine DCIKMF2 Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Fenoprofen + Triflupromazine DCG9IQO Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Fomepizole + Triflupromazine DCTV032 Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Hyodeoxycholic acid + Triflupromazine DCCHQ3G Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Imatinib + Triflupromazine DCFGCIX Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
IT-141 + Triflupromazine DCDTG7C IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Levamisole + Triflupromazine DCFEIMP Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Memantine + Triflupromazine DCCJQIE Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Methylergonovine + Triflupromazine DCFZ760 Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Metyrosine + Triflupromazine DCKAW1L Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Naringenin + Triflupromazine DC2DJ6D Naringenin Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Olmesartan medoxomil + Triflupromazine DCTURIR Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
PF-02545920 + Triflupromazine DC3BMZX PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Pinacidil + Triflupromazine DC80AA0 Pinacidil Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Probenecid + Triflupromazine DCCCFSL Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Procarbazine + Triflupromazine DCHCRTO Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Pyrazinamide + Triflupromazine DC2V2DL Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Ramelteon + Triflupromazine DCRQVWZ Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
SCH 727965 + Triflupromazine DC6K7GW SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Sulfinpyrazone + Triflupromazine DCA4LVP Sulfinpyrazone Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Teriflunomide + Triflupromazine DC0MCS9 Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Topotecan + Triflupromazine DCXARTJ Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [6]
Triapine + Triflupromazine DCGQUYA Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [6]
Triflupromazine + Aprepitant DCVDP0T Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Lefaxin DC41MLS Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Baclofen DCZ4JOM Baclofen Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Gefitinib DCUQL8A Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Diethylcarbamazine DCDYA4I Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Lumefantrine DCA6CJM Lumefantrine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Epinephrine DCHXHN6 Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + PMID28460551-Compound-2 DCREPAG PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Vinblastine DCPSFI6 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Anamorelin DCHJ1YI Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Pazopanib HCl DCVOKHK Pazopanib HCl Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Ezetimibe DCLKFVJ Ezetimibe Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + IT-141 DCETN8D IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Pamidronate DCVQ9YS Pamidronate Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Isosorbide dinitrate DCE0UOA Isosorbide dinitrate Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Terameprocol DCWRAB1 Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Itraconazole DC40T5G Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Carglumic acid DCE762U Carglumic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Docetaxel DC3EKU5 Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + WAY-100635 DCL6UAF WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + PHA-739358 DCULX4Y PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Pentamidine DC03EGW Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Tolazoline DC4OK13 Tolazoline Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Tolvaptan DCKC38Z Tolvaptan Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Triflupromazine DC3C87K Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + BIO-300 DC84SKD BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Niclosamide DC7DULM Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Lubiprostone DC2MTRJ Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Tiagabine DC7ZSUL Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Oseltamivir DCI48QX Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Diazoxide DC6GYSG Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Tamoxifen DCXMS02 Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Benserazide DCH43GC Benserazide Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Idarubicin DC8SXAJ Idarubicin Glioblastoma? (Cell Line: T98G) [5]
Triflupromazine + Probenecid DCOYTTQ Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Bortezomib DC1PNUU Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Methylene blue DCBFYQS Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Tropisetron DCZIRN7 Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Maprotiline DCSYZZZ Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Oxyphenbutazone DCEH98W Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Acetohexamide DCCBREM Acetohexamide Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Ethambutol DCU0I0Y Ethambutol Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Novobiocin DCDEDOL Novobiocin Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Chlorambucil DC4XXVH Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Endoxifen DC9LV2H Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Mycophenolic acid DC1T3WI Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Cisatracurium DCP3L6L Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Mefloquine DC804QN Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Pizotyline DCUXIUT Pizotyline Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Doxorubicin DCY5CSF Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Testolactone DCL52DY Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Sumatriptan DCUVCNK Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Auranofin DC3ZX8D Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
Triflupromazine + Atovaquone DCDWEQM Atovaquone Chronic myelogenous leukemia (Cell Line: KBM-7) [5]
------------------------------------------------------------------------------------
⏷ Show the Full List of 96 DrugCom(s)

References

1 Triflupromazine FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4330).
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
4 Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrob Agents Chemother. 2014 Aug;58(8):4885-93.
5 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
6 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.